(73 nodes) Negative regulation of cell cycle network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_04491	WD_REPEATS_REGION domain-containing protein. (362 aa)
	T265_15946	BRCT domain-containing protein. (135 aa)
	T265_11218	Uncharacterized protein. (114 aa)
	T265_11182	Protein kinase domain-containing protein. (869 aa)
	T265_11981	ATPase, AAA family. (1335 aa)
	T265_15197	WD_REPEATS_REGION domain-containing protein. (677 aa)
	T265_10458	Uncharacterized protein. (420 aa)
	T265_09418	HORMA domain protein. (202 aa)
	T265_10535	FCP1 homology domain-containing protein. (724 aa)
	T265_09312	Uncharacterized protein. (1002 aa)
	T265_10444	CDT1 domain-containing protein. (680 aa)
	T265_09227	Uncharacterized protein. (973 aa)
	T265_14653	Uncharacterized protein. (220 aa)
	T265_08599	Uncharacterized protein. (1188 aa)
	T265_08544	WD_REPEATS_REGION domain-containing protein. (860 aa)
	T265_14629	RGS domain-containing protein. (628 aa)
	T265_08399	WW domain-containing protein. (1101 aa)
	T265_14564	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1512 aa)
	T265_15380	Helicase C-terminal domain-containing protein. (1185 aa)
	T265_11217	Uncharacterized protein. (91 aa)
	T265_14481	G-patch domain-containing protein. (290 aa)
	T265_07924	Uncharacterized protein. (368 aa)
	T265_07774	Uncharacterized protein. (1466 aa)
	T265_07721	Uncharacterized protein. (203 aa)
	T265_08733	Uncharacterized protein. (161 aa)
	T265_07048	Uncharacterized protein. (576 aa)
	T265_15013	WAPL domain-containing protein. (1579 aa)
	T265_06748	Nudix hydrolase domain-containing protein. (263 aa)
	T265_06520	C3H1-type domain-containing protein. (253 aa)
	T265_07722	Protein kinase domain-containing protein. (793 aa)
	T265_07450	Zinc finger, C2H2 type. (518 aa)
	T265_05628	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (815 aa)
	T265_14119	Uncharacterized protein. (1633 aa)
	T265_13819	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (774 aa)
	T265_14026	Uncharacterized protein. (228 aa)
	T265_05138	Uncharacterized protein. (564 aa)
	T265_14381	Uncharacterized protein. (1442 aa)
	T265_04361	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (470 aa)
	T265_03805	Uncharacterized protein. (614 aa)
	T265_04950	U1-type domain-containing protein. (275 aa)
	T265_13509	Uncharacterized protein. (933 aa)
	T265_16154	U-box domain-containing protein. (118 aa)
	T265_05933	FYVE-type domain-containing protein. (261 aa)
	T265_13071	Uncharacterized protein. (459 aa)
	T265_02588	TPR_MLP1_2 domain-containing protein. (2563 aa)
	T265_02098	Uncharacterized protein. (493 aa)
	T265_02103	PI3K/PI4K domain-containing protein. (4230 aa)
	T265_13075	Uncharacterized protein. (1021 aa)
	T265_11221	Uncharacterized protein. (471 aa)
	T265_02531	Uncharacterized protein. (198 aa)
	T265_02097	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2379 aa)
	T265_12899	FHA domain-containing protein. (420 aa)
	T265_12681	Elp3 domain-containing protein. (370 aa)
	T265_10513	Uncharacterized protein. (182 aa)
	T265_03790	Uncharacterized protein. (1181 aa)
	T265_01334	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (577 aa)
	T265_12528	Uncharacterized protein. (1533 aa)
	T265_09218	Uncharacterized protein. (517 aa)
	T265_12502	Uncharacterized protein. (600 aa)
	T265_00347	Uncharacterized protein. (1449 aa)
	T265_12455	Uncharacterized protein. (871 aa)
	T265_08608	RGS domain-containing protein. (671 aa)
	T265_02061	BRCT domain-containing protein. (1151 aa)
	T265_12558	Protein kinase domain-containing protein. (1336 aa)
	T265_00205	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3232 aa)
	T265_00149	C2H2-type domain-containing protein. (625 aa)
	T265_06410	53-BP1_Tudor domain-containing protein. (948 aa)
	T265_06122	NIBRIN_BRCT_II domain-containing protein. (720 aa)
	T265_05790	ERCC4 domain-containing protein. (795 aa)
	T265_05041	Uncharacterized protein. (2064 aa)
	T265_13602	Rod_C domain-containing protein. (2308 aa)
	T265_04386	Uncharacterized protein. (1966 aa)
	T265_13166	Uncharacterized protein. (485 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00205	T265_00347	A0A075AD54	A0A075A6C3	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.690
T265_00205	T265_02061	A0A075AD54	A0A075A815	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	BRCT domain-containing protein.	0.771
T265_00205	T265_02097	A0A075AD54	A0A075A0G4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.960
T265_00205	T265_02098	A0A075AD54	A0A074ZWB3	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.960
T265_00205	T265_02103	A0A075AD54	A0A074ZWB6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	PI3K/PI4K domain-containing protein.	0.698
T265_00205	T265_02531	A0A075AD54	A0A074ZZ12	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.900
T265_00205	T265_04386	A0A075AD54	A0A075AGL6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.698
T265_00205	T265_05138	A0A075AD54	A0A074ZKS2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.928
T265_00205	T265_05628	A0A075AD54	A0A074ZIZ6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.986
T265_00205	T265_05790	A0A075AD54	A0A075AEV1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	ERCC4 domain-containing protein.	0.734
T265_00205	T265_06122	A0A075AD54	A0A075AEG4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	NIBRIN_BRCT_II domain-containing protein.	0.989
T265_00205	T265_06410	A0A075AD54	A0A075ADU6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	53-BP1_Tudor domain-containing protein.	0.844
T265_00205	T265_07924	A0A075AD54	A0A074ZAS8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.595
T265_00205	T265_08599	A0A075AD54	A0A074Z8Q4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.536
T265_00205	T265_09218	A0A075AD54	A0A075A5Q0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.948
T265_00205	T265_09227	A0A075AD54	A0A074Z6Q1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.538
T265_00205	T265_10458	A0A075AD54	A0A074Z2F2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.728
T265_00205	T265_11182	A0A075AD54	A0A074YZM1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.728
T265_00205	T265_11217	A0A075AD54	A0A074ZAE5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.690
T265_00205	T265_11218	A0A075AD54	A0A074YZJ9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.690