(33 nodes) Alcohol biosynthetic process network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_15281	Uncharacterized protein. (178 aa)
	T265_10018	Uncharacterized protein. (671 aa)
	T265_10585	DJ-1_PfpI domain-containing protein. (210 aa)
	T265_11156	Uncharacterized protein. (565 aa)
	T265_07882	Uncharacterized protein. (618 aa)
	T265_10222	Nudix hydrolase domain-containing protein. (417 aa)
	T265_14432	Kinase; Belongs to the inositol phosphokinase (IPK) family. (400 aa)
	T265_07802	Kinase; Belongs to the inositol phosphokinase (IPK) family. (453 aa)
	T265_05841	Uncharacterized protein. (731 aa)
	T265_13808	Uncharacterized protein. (225 aa)
	T265_05558	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (491 aa)
	T265_05309	Phosphoenolpyruvate carboxykinase. (636 aa)
	T265_13542	Neutral ceramidase. (708 aa)
	T265_06306	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (513 aa)
	T265_00911	Uncharacterized protein. (131 aa)
	T265_00972	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1621 aa)
	T265_03200	DAGKc domain-containing protein. (542 aa)
	T265_04895	Aminotran_1_2 domain-containing protein. (607 aa)
	T265_00247	Alkyl transferase; Belongs to the UPP synthase family. (325 aa)
	T265_00912	Uncharacterized protein. (1076 aa)
	T265_12761	Uncharacterized protein. (180 aa)
	T265_01360	Aspartate aminotransferase. (411 aa)
	T265_08178	Uncharacterized protein. (137 aa)
	T265_09631	Uncharacterized protein. (136 aa)
	T265_01752	Mevalonate kinase. (415 aa)
	T265_04306	Putative 4a-hydroxytetrahydrobiopterin dehydratase. (108 aa)
	T265_10887	Uncharacterized protein. (182 aa)
	T265_02495	GTP_cyclohydroI domain-containing protein. (410 aa)
	T265_02493	GTP_cyclohydroI domain-containing protein. (345 aa)
	T265_03185	Kinase; Belongs to the inositol phosphokinase (IPK) family. (327 aa)
	T265_11435	S5A_REDUCTASE domain-containing protein. (255 aa)
	T265_15495	Uncharacterized protein. (177 aa)
	T265_15401	DJ-1 family protein. (183 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00247	T265_01752	A0A075AD93	A0A075A1L8	Alkyl transferase; Belongs to the UPP synthase family.	Mevalonate kinase.	0.539
T265_00247	T265_06306	A0A075AD93	A0A074ZSU0	Alkyl transferase; Belongs to the UPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.518
T265_00247	T265_08178	A0A075AD93	A0A075A997	Alkyl transferase; Belongs to the UPP synthase family.	Uncharacterized protein.	0.999
T265_00247	T265_10222	A0A075AD93	A0A074ZE32	Alkyl transferase; Belongs to the UPP synthase family.	Nudix hydrolase domain-containing protein.	0.855
T265_00247	T265_11156	A0A075AD93	A0A074ZAK6	Alkyl transferase; Belongs to the UPP synthase family.	Uncharacterized protein.	0.532
T265_00247	T265_11435	A0A075AD93	A0A074ZXG7	Alkyl transferase; Belongs to the UPP synthase family.	S5A_REDUCTASE domain-containing protein.	0.642
T265_00972	T265_03185	A0A075AJB1	A0A074ZWQ7	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.534
T265_00972	T265_05558	A0A075AJB1	A0A074ZK03	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).	0.962
T265_00972	T265_13808	A0A075AJB1	A0A074ZJ61	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	Uncharacterized protein.	0.457
T265_00972	T265_14432	A0A075AJB1	A0A074ZFK0	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.534
T265_01360	T265_04306	A0A075AAB3	A0A075A0C9	Aspartate aminotransferase.	Putative 4a-hydroxytetrahydrobiopterin dehydratase.	0.803
T265_01360	T265_05309	A0A075AAB3	A0A074ZKX7	Aspartate aminotransferase.	Phosphoenolpyruvate carboxykinase.	0.826
T265_01360	T265_07882	A0A075AAB3	A0A074ZAX5	Aspartate aminotransferase.	Uncharacterized protein.	0.826
T265_01752	T265_00247	A0A075A1L8	A0A075AD93	Mevalonate kinase.	Alkyl transferase; Belongs to the UPP synthase family.	0.539
T265_01752	T265_04895	A0A075A1L8	A0A075AFZ5	Mevalonate kinase.	Aminotran_1_2 domain-containing protein.	0.581
T265_01752	T265_06306	A0A075A1L8	A0A074ZSU0	Mevalonate kinase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.855
T265_01752	T265_08178	A0A075A1L8	A0A075A997	Mevalonate kinase.	Uncharacterized protein.	0.539
T265_01752	T265_09631	A0A075A1L8	A0A075A4C0	Mevalonate kinase.	Uncharacterized protein.	0.548
T265_01752	T265_10018	A0A075A1L8	A0A074Z3X2	Mevalonate kinase.	Uncharacterized protein.	0.663
T265_01752	T265_10222	A0A075A1L8	A0A074ZE32	Mevalonate kinase.	Nudix hydrolase domain-containing protein.	0.811