(101 nodes) Negative regulation of cellular component organization network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_14629	RGS domain-containing protein. (628 aa)
	T265_02060	LIM zinc-binding domain-containing protein. (425 aa)
	T265_12997	Uncharacterized protein. (956 aa)
	T265_13055	Spectrin repeat-containing domain protein. (2421 aa)
	T265_13166	Uncharacterized protein. (485 aa)
	T265_04495	Ku domain-containing protein. (974 aa)
	T265_13602	Rod_C domain-containing protein. (2308 aa)
	T265_13828	Uncharacterized protein. (2060 aa)
	T265_12558	Protein kinase domain-containing protein. (1336 aa)
	T265_12544	Uncharacterized protein. (69 aa)
	T265_07174	Uncharacterized protein. (483 aa)
	T265_07583	Reverse transcriptase domain-containing protein. (1295 aa)
	T265_14359	Uncharacterized protein. (3872 aa)
	T265_08393	Uncharacterized protein. (441 aa)
	T265_08608	RGS domain-containing protein. (671 aa)
	T265_02246	PH domain-containing protein. (1257 aa)
	T265_00215	Integrase catalytic domain-containing protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (639 aa)
	T265_14722	Uncharacterized protein. (1428 aa)
	T265_02435	Spectrin beta chain; Belongs to the spectrin family. (2345 aa)
	T265_02528	RWD domain protein. (329 aa)
	T265_00442	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (450 aa)
	T265_14940	Uncharacterized protein. (183 aa)
	T265_00248	Uncharacterized protein. (1143 aa)
	T265_00019	Aldolase_II domain-containing protein. (809 aa)
	T265_09919	Uncharacterized protein. (2924 aa)
	T265_00449	Uncharacterized protein. (135 aa)
	T265_00440	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (323 aa)
	T265_12596	Uncharacterized protein. (384 aa)
	T265_12543	Uncharacterized protein. (206 aa)
	T265_03906	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (364 aa)
	T265_00896	UDENN FLCN/SMCR8-type domain-containing protein. (723 aa)
	T265_12731	ADF-H domain-containing protein. (317 aa)
	T265_04518	Uncharacterized protein. (3031 aa)
	T265_12962	Calponin-homology (CH) domain-containing protein. (1454 aa)
	T265_04572	Glycolipid transfer protein. (227 aa)
	T265_11236	Uncharacterized protein. (237 aa)
	T265_15386	MAT1 domain-containing protein. (1203 aa)
	T265_13075	Uncharacterized protein. (1021 aa)
	T265_02911	Protein kinase domain-containing protein. (624 aa)
	T265_02953	Uncharacterized protein. (510 aa)
	T265_05089	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (307 aa)
	T265_01892	Sema domain-containing protein. (1113 aa)
	T265_12961	Uncharacterized protein. (850 aa)
	T265_05447	Uncharacterized protein. (542 aa)
	T265_02588	TPR_MLP1_2 domain-containing protein. (2563 aa)
	T265_13064	PRELI/MSF1 domain-containing protein. (172 aa)
	T265_13334	Uncharacterized protein. (687 aa)
	T265_02910	Protein kinase domain-containing protein. (429 aa)
	T265_03005	Uncharacterized protein. (1043 aa)
	T265_06721	Sema domain-containing protein. (297 aa)
	T265_03559	Sema domain-containing protein. (1306 aa)
	T265_03970	HRDC domain-containing protein. (946 aa)
	T265_03805	Uncharacterized protein. (614 aa)
	T265_14226	Uncharacterized protein. (1035 aa)
	T265_13381	DNA helicase; Belongs to the MCM family. (889 aa)
	T265_07694	ANK_REP_REGION domain-containing protein. (239 aa)
	T265_04491	WD_REPEATS_REGION domain-containing protein. (362 aa)
	T265_05897	CKK domain-containing protein. (1253 aa)
	T265_07818	Uncharacterized protein. (357 aa)
	T265_06343	TACC_C domain-containing protein. (1889 aa)
	T265_14581	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (365 aa)
	T265_06755	Uncharacterized protein. (513 aa)
	T265_06747	Uncharacterized protein. (383 aa)
	T265_05848	Uncharacterized protein. (285 aa)
	T265_13935	Sema domain-containing protein. (1327 aa)
	T265_06160	Tyrosine-protein phosphatase domain-containing protein. (213 aa)
	T265_06453	HP domain-containing protein. (2398 aa)
	T265_07722	Protein kinase domain-containing protein. (793 aa)
	T265_09658	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (329 aa)
	T265_06608	Aldolase_II domain-containing protein. (713 aa)
	T265_14941	Sema domain-containing protein. (324 aa)
	T265_07878	TFCD_C domain-containing protein. (1119 aa)
	T265_06716	Uncharacterized protein. (961 aa)
	T265_06746	Uncharacterized protein. (448 aa)
	T265_15013	WAPL domain-containing protein. (1579 aa)
	T265_10284	Uncharacterized protein. (302 aa)
	T265_08507	ANK_REP_REGION domain-containing protein. (667 aa)
	T265_14358	Uncharacterized protein. (148 aa)
	T265_08999	Poly [ADP-ribose] polymerase. (1742 aa)
	T265_07721	Uncharacterized protein. (203 aa)
	T265_07774	Uncharacterized protein. (1466 aa)
	T265_14481	G-patch domain-containing protein. (290 aa)
	T265_09374	Uncharacterized protein. (625 aa)
	T265_11237	Uncharacterized protein. (190 aa)
	T265_11632	PH domain-containing protein. (1305 aa)
	T265_09418	HORMA domain protein. (202 aa)
	T265_10701	F-BAR domain-containing protein. (538 aa)
	T265_09749	Uncharacterized protein. (1070 aa)
	T265_10087	Uncharacterized protein. (181 aa)
	T265_11342	Uncharacterized protein. (744 aa)
	T265_11981	ATPase, AAA family. (1335 aa)
	T265_10980	Uncharacterized protein. (1014 aa)
	T265_11235	Uncharacterized protein. (384 aa)
	T265_15873	Telo_bind domain-containing protein. (110 aa)
	T265_12211	Uncharacterized protein. (121 aa)
	T265_11238	Uncharacterized protein. (454 aa)
	T265_16109	Uncharacterized protein. (164 aa)
	T265_16184	Uncharacterized protein. (164 aa)
	T265_15623	Telo_bind domain-containing protein. (725 aa)
	T265_16021	Uncharacterized protein. (135 aa)
	T265_16293	Uncharacterized protein. (110 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00019	T265_05089	A0A075A3A7	A0A074ZX82	Aldolase_II domain-containing protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.417
T265_00248	T265_03970	A0A075A3Y0	A0A074ZQJ4	Uncharacterized protein.	HRDC domain-containing protein.	0.673
T265_00440	T265_05447	A0A075A334	A0A074ZW19	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Uncharacterized protein.	0.929
T265_00442	T265_05447	A0A075A623	A0A074ZW19	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Uncharacterized protein.	0.929
T265_02246	T265_12962	A0A075A727	A0A074ZZM8	PH domain-containing protein.	Calponin-homology (CH) domain-containing protein.	0.424
T265_02246	T265_13055	A0A075A727	A0A075AI56	PH domain-containing protein.	Spectrin repeat-containing domain protein.	0.833
T265_02246	T265_14359	A0A075A727	A0A075AAW6	PH domain-containing protein.	Uncharacterized protein.	0.483
T265_02435	T265_03906	A0A075A6I1	A0A075A1K5	Spectrin beta chain; Belongs to the spectrin family.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.422
T265_02435	T265_05089	A0A075A6I1	A0A074ZX82	Spectrin beta chain; Belongs to the spectrin family.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.447
T265_02435	T265_08999	A0A075A6I1	A0A074ZBS6	Spectrin beta chain; Belongs to the spectrin family.	Poly [ADP-ribose] polymerase.	0.775
T265_02435	T265_13055	A0A075A6I1	A0A075AI56	Spectrin beta chain; Belongs to the spectrin family.	Spectrin repeat-containing domain protein.	0.985
T265_02435	T265_14359	A0A075A6I1	A0A075AAW6	Spectrin beta chain; Belongs to the spectrin family.	Uncharacterized protein.	0.483
T265_02588	T265_03805	A0A074ZVL2	A0A074ZQB3	TPR_MLP1_2 domain-containing protein.	Uncharacterized protein.	0.606
T265_02588	T265_14359	A0A074ZVL2	A0A075AAW6	TPR_MLP1_2 domain-containing protein.	Uncharacterized protein.	0.401
T265_02910	T265_02911	A0A074ZTD3	A0A074ZXM0	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.900
T265_02910	T265_14359	A0A074ZTD3	A0A075AAW6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.400
T265_02911	T265_02910	A0A074ZXM0	A0A074ZTD3	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.900
T265_02911	T265_14359	A0A074ZXM0	A0A075AAW6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.400
T265_03005	T265_05089	A0A074ZTD0	A0A074ZX82	Uncharacterized protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.417
T265_03805	T265_02588	A0A074ZQB3	A0A074ZVL2	Uncharacterized protein.	TPR_MLP1_2 domain-containing protein.	0.606