(11 nodes) NAD+ binding network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_10265	Deacetylase sirtuin-type domain-containing protein. (374 aa)
	T265_14142	Deacetylase sirtuin-type domain-containing protein. (349 aa)
	T265_13984	Uncharacterized protein. (321 aa)
	T265_03573	Deacetylase sirtuin-type domain-containing protein. (477 aa)
	T265_04278	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (307 aa)
	T265_04119	NAD(P)-bd_dom domain-containing protein. (324 aa)
	T265_05947	Deacetylase sirtuin-type domain-containing protein. (510 aa)
	T265_15604	Deacetylase sirtuin-type domain-containing protein. (466 aa)
	T265_08445	Deacetylase sirtuin-type domain-containing protein. (947 aa)
	T265_08169	Uncharacterized protein. (930 aa)
	T265_13112	Deacetylase sirtuin-type domain-containing protein. (1694 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_03573	T265_04278	A0A074ZRX7	A0A074ZT22	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.967
T265_03573	T265_05947	A0A074ZRX7	A0A074ZU15	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.972
T265_03573	T265_08445	A0A074ZRX7	A0A075A8D7	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.962
T265_03573	T265_10265	A0A074ZRX7	A0A074Z316	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.960
T265_03573	T265_13112	A0A074ZRX7	A0A075AHZ3	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.447
T265_03573	T265_14142	A0A074ZRX7	A0A074ZEQ5	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.956
T265_03573	T265_15604	A0A074ZRX7	A0A074ZVQ7	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.940
T265_04119	T265_08169	A0A074ZTR4	A0A075A985	NAD(P)-bd_dom domain-containing protein.	Uncharacterized protein.	0.427
T265_04278	T265_03573	A0A074ZT22	A0A074ZRX7	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Deacetylase sirtuin-type domain-containing protein.	0.967
T265_04278	T265_05947	A0A074ZT22	A0A074ZU15	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Deacetylase sirtuin-type domain-containing protein.	0.947
T265_04278	T265_08445	A0A074ZT22	A0A075A8D7	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Deacetylase sirtuin-type domain-containing protein.	0.922
T265_04278	T265_10265	A0A074ZT22	A0A074Z316	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Deacetylase sirtuin-type domain-containing protein.	0.940
T265_04278	T265_13112	A0A074ZT22	A0A075AHZ3	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Deacetylase sirtuin-type domain-containing protein.	0.664
T265_04278	T265_14142	A0A074ZT22	A0A074ZEQ5	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Deacetylase sirtuin-type domain-containing protein.	0.922
T265_04278	T265_15604	A0A074ZT22	A0A074ZVQ7	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Deacetylase sirtuin-type domain-containing protein.	0.960
T265_05947	T265_03573	A0A074ZU15	A0A074ZRX7	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.972
T265_05947	T265_04278	A0A074ZU15	A0A074ZT22	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.947
T265_05947	T265_08445	A0A074ZU15	A0A075A8D7	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.941
T265_05947	T265_10265	A0A074ZU15	A0A074Z316	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.938
T265_05947	T265_13112	A0A074ZU15	A0A075AHZ3	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.643