(75 nodes) Translation regulator activity, nucleic acid binding network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_12915	Eukaryotic translation initiation factor 3 subunit A. (838 aa)
	T265_14962	Tr-type G domain-containing protein. (513 aa)
	T265_16085	GTP_EFTU_D3 domain-containing protein. (53 aa)
	T265_15927	Uncharacterized protein. (74 aa)
	T265_16333	eIF3g domain-containing protein. (93 aa)
	T265_15974	eIF3g domain-containing protein. (76 aa)
	T265_15598	Uncharacterized protein. (756 aa)
	T265_11234	Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (591 aa)
	T265_12355	Uncharacterized protein. (72 aa)
	T265_16171	Uncharacterized protein. (100 aa)
	T265_14909	PCI domain-containing protein. (533 aa)
	T265_15639	Uncharacterized protein. (383 aa)
	T265_08648	SUI1 domain-containing protein. (120 aa)
	T265_08593	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (553 aa)
	T265_08315	MPN domain-containing protein. (340 aa)
	T265_11314	Tr-type G domain-containing protein. (107 aa)
	T265_11007	Tr-type G domain-containing protein. (720 aa)
	T265_14200	eIF2A domain-containing protein. (501 aa)
	T265_06846	Peptide chain release factor eRF/aRF, subunit 1. (440 aa)
	T265_08002	eIF2B_5 domain-containing protein. (436 aa)
	T265_14110	Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (817 aa)
	T265_06314	RRM domain-containing protein. (731 aa)
	T265_14236	PCI domain-containing protein; Belongs to the eIF-3 subunit E family. (430 aa)
	T265_07133	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (461 aa)
	T265_14744	Uncharacterized protein. (655 aa)
	T265_05507	Uncharacterized protein. (198 aa)
	T265_13768	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (858 aa)
	T265_06361	MIF4G domain-containing protein. (1138 aa)
	T265_13921	Tr-type G domain-containing protein. (574 aa)
	T265_05960	Uncharacterized protein. (436 aa)
	T265_04631	Uncharacterized protein. (248 aa)
	T265_04737	Uncharacterized protein. (560 aa)
	T265_04430	Uncharacterized protein. (233 aa)
	T265_13782	Uncharacterized protein; Belongs to the DEAD box helicase family. (455 aa)
	T265_13385	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (597 aa)
	T265_07162	MPN domain-containing protein. (394 aa)
	T265_09909	eIF-5a domain-containing protein. (192 aa)
	T265_15043	Tr-type G domain-containing protein. (708 aa)
	T265_13362	Tr-type G domain-containing protein. (666 aa)
	T265_03929	RRM domain-containing protein. (1002 aa)
	T265_05147	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (674 aa)
	T265_16372	RRM domain-containing protein. (52 aa)
	T265_03569	Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (391 aa)
	T265_03345	RF_PROK_I domain-containing protein. (164 aa)
	T265_03124	S1 motif domain-containing protein. (329 aa)
	T265_15910	Uncharacterized protein. (229 aa)
	T265_13383	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (521 aa)
	T265_12092	Uncharacterized protein. (540 aa)
	T265_15234	Uncharacterized protein. (129 aa)
	T265_01075	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (259 aa)
	T265_10927	Tr-type G domain-containing protein. (691 aa)
	T265_01495	eIF4-gamma/eIF5/eIF2-epsilon. (772 aa)
	T265_01549	Uncharacterized protein. (409 aa)
	T265_13603	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (901 aa)
	T265_11313	Uncharacterized protein. (106 aa)
	T265_01765	RF_PROK_I domain-containing protein. (446 aa)
	T265_15431	Uncharacterized protein. (606 aa)
	T265_03355	Uncharacterized protein. (285 aa)
	T265_12086	Uncharacterized protein; Belongs to the DEAD box helicase family. (333 aa)
	T265_00007	Integrase catalytic domain-containing protein. (526 aa)
	T265_12486	Tr-type G domain-containing protein. (945 aa)
	T265_01587	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (201 aa)
	T265_01102	Uncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (289 aa)
	T265_00778	W2 domain-containing protein. (1358 aa)
	T265_13005	Uncharacterized protein. (548 aa)
	T265_02241	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (669 aa)
	T265_01214	W2 domain-containing protein. (442 aa)
	T265_00277	Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (178 aa)
	T265_06555	Uncharacterized protein. (924 aa)
	T265_05509	SUI1 domain-containing protein. (269 aa)
	T265_05298	Tr-type G domain-containing protein. (867 aa)
	T265_13550	RRM domain-containing protein. (630 aa)
	T265_04525	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (446 aa)
	T265_03946	Tr-type G domain-containing protein. (1242 aa)
	T265_03058	Tr-type G domain-containing protein. (465 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00007	T265_00778	A0A075AJX0	A0A075A4S2	Integrase catalytic domain-containing protein.	W2 domain-containing protein.	0.861
T265_00007	T265_01214	A0A075AJX0	A0A075AAE4	Integrase catalytic domain-containing protein.	W2 domain-containing protein.	0.811
T265_00007	T265_02241	A0A075AJX0	A0A075A7G9	Integrase catalytic domain-containing protein.	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs.	0.452
T265_00007	T265_03058	A0A075AJX0	A0A075AHW3	Integrase catalytic domain-containing protein.	Tr-type G domain-containing protein.	0.567
T265_00007	T265_03124	A0A075AJX0	A0A074ZTR9	Integrase catalytic domain-containing protein.	S1 motif domain-containing protein.	0.755
T265_00007	T265_03355	A0A075AJX0	A0A074ZWE8	Integrase catalytic domain-containing protein.	Uncharacterized protein.	0.550
T265_00007	T265_04631	A0A075AJX0	A0A074ZMH3	Integrase catalytic domain-containing protein.	Uncharacterized protein.	0.553
T265_00007	T265_05147	A0A075AJX0	A0A074ZQ46	Integrase catalytic domain-containing protein.	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	0.736
T265_00007	T265_05298	A0A075AJX0	A0A075AFF4	Integrase catalytic domain-containing protein.	Tr-type G domain-containing protein.	0.525
T265_00007	T265_06361	A0A075AJX0	A0A074ZKS0	Integrase catalytic domain-containing protein.	MIF4G domain-containing protein.	0.861
T265_00007	T265_06846	A0A075AJX0	A0A074ZEY5	Integrase catalytic domain-containing protein.	Peptide chain release factor eRF/aRF, subunit 1.	0.435
T265_00007	T265_07162	A0A075AJX0	A0A074ZPV9	Integrase catalytic domain-containing protein.	MPN domain-containing protein.	0.521
T265_00007	T265_08002	A0A075AJX0	A0A074ZFA6	Integrase catalytic domain-containing protein.	eIF2B_5 domain-containing protein.	0.725
T265_00007	T265_08315	A0A075AJX0	A0A074Z9I7	Integrase catalytic domain-containing protein.	MPN domain-containing protein.	0.494
T265_00007	T265_08648	A0A075AJX0	A0A074Z8E7	Integrase catalytic domain-containing protein.	SUI1 domain-containing protein.	0.452
T265_00007	T265_12086	A0A075AJX0	A0A074ZUR4	Integrase catalytic domain-containing protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.817
T265_00007	T265_12915	A0A075AJX0	A0A075AIL1	Integrase catalytic domain-containing protein.	Eukaryotic translation initiation factor 3 subunit A.	0.426
T265_00007	T265_13550	A0A075AJX0	A0A075AGA8	Integrase catalytic domain-containing protein.	RRM domain-containing protein.	0.475
T265_00007	T265_13603	A0A075AJX0	A0A074ZYD3	Integrase catalytic domain-containing protein.	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.504
T265_00007	T265_13782	A0A075AJX0	A0A074ZNY9	Integrase catalytic domain-containing protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.817