(36 nodes) ATPase, AAA-type, core network (Opisthorchis viverrini)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	T265_09503	AAA domain-containing protein; Belongs to the AAA ATPase family. (398 aa)
	T265_08088	ATPase, AAA family. (874 aa)
	T265_08672	AAA domain-containing protein. (603 aa)
	T265_09935	Uncharacterized protein; Belongs to the AAA ATPase family. (827 aa)
	T265_08645	AAA domain-containing protein; Belongs to the AAA ATPase family. (623 aa)
	T265_10916	ATPase, AAA family; Belongs to the AAA ATPase family. (465 aa)
	T265_10613	ATPase, AAA family; Belongs to the AAA ATPase family. (486 aa)
	T265_11981	ATPase, AAA family. (1335 aa)
	T265_11438	AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
	T265_11068	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1042 aa)
	T265_14343	AAA domain-containing protein. (913 aa)
	KATNAL2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (612 aa)
	T265_09385	AAA domain-containing protein. (1608 aa)
	T265_13940	Uncharacterized protein. (2358 aa)
	T265_04782	AAA domain-containing protein. (721 aa)
	T265_04361	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (470 aa)
	T265_07312	AAA domain-containing protein. (586 aa)
	T265_13205	AAA domain-containing protein; Belongs to the AAA ATPase family. (426 aa)
	T265_02963	Uncharacterized protein. (856 aa)
	T265_13304	AAA domain-containing protein. (339 aa)
	T265_01982	AAA domain-containing protein; Belongs to the AAA ATPase family. (386 aa)
	T265_12911	Uncharacterized protein. (846 aa)
	T265_01989	DNA helicase; Belongs to the RuvB family. (887 aa)
	T265_02769	Uncharacterized protein. (867 aa)
	T265_02110	Replication factor C subunit 1. (1093 aa)
	T265_10611	AAA domain-containing protein; Belongs to the AAA ATPase family. (442 aa)
	T265_15132	Bromo domain-containing protein. (1613 aa)
	T265_10217	AAA domain-containing protein; Belongs to the AAA ATPase family. (292 aa)
	T265_01334	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (577 aa)
	T265_12427	AAA domain-containing protein; Belongs to the AAA ATPase family. (493 aa)
	T265_03153	ATPase_AAA_core domain-containing protein. (804 aa)
	T265_09502	AAA domain-containing protein. (274 aa)
	T265_08813	AAA domain-containing protein; Belongs to the AAA ATPase family. (417 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (598 aa)
	T265_01429	AAA domain-containing protein. (1033 aa)
	T265_11499	AAA domain-containing protein; Belongs to the AAA ATPase family. (626 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KATNA1	T265_01982	A0A075A8S1	A0A074ZWR2	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.626
KATNA1	T265_01989	A0A075A8S1	A0A074ZXT9	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	DNA helicase; Belongs to the RuvB family.	0.447
KATNA1	T265_04361	A0A075A8S1	A0A074ZP46	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.431
KATNA1	T265_08813	A0A075A8S1	A0A075A763	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.622
KATNA1	T265_10217	A0A075A8S1	A0A075A223	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.628
KATNAL2	T265_01334	A0A074ZGH5	A0A075A351	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.471
KATNAL2	T265_01429	A0A074ZGH5	A0A075A9X2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	AAA domain-containing protein.	0.417
KATNAL2	T265_01982	A0A074ZGH5	A0A074ZWR2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.895
KATNAL2	T265_01989	A0A074ZGH5	A0A074ZXT9	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	DNA helicase; Belongs to the RuvB family.	0.494
KATNAL2	T265_04361	A0A074ZGH5	A0A074ZP46	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.659
KATNAL2	T265_08088	A0A074ZGH5	A0A074ZAA9	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	ATPase, AAA family.	0.409
KATNAL2	T265_08672	A0A074ZGH5	A0A074Z8J4	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	AAA domain-containing protein.	0.635
KATNAL2	T265_08813	A0A074ZGH5	A0A075A763	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.896
KATNAL2	T265_09502	A0A074ZGH5	A0A075A4P2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	AAA domain-containing protein.	0.475
KATNAL2	T265_09503	A0A074ZGH5	A0A074ZGK8	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.467
KATNAL2	T265_10217	A0A074ZGH5	A0A075A223	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.895
KATNAL2	T265_10916	A0A074ZGH5	A0A074Z4V9	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	ATPase, AAA family; Belongs to the AAA ATPase family.	0.432
KATNAL2	T265_11981	A0A074ZGH5	A0A074Z124	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	ATPase, AAA family.	0.416
KATNAL2	T265_12911	A0A074ZGH5	A0A074ZXI9	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Uncharacterized protein.	0.543
KATNAL2	T265_13304	A0A074ZGH5	A0A074ZVA6	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	AAA domain-containing protein.	0.400