(28 nodes) Aldolase-type TIM barrel network (Opisthorchis viverrini)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	T265_00618	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (411 aa)
	T265_07976	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (362 aa)
	T265_14007	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (523 aa)
	T265_15557	Reverse transcriptase domain-containing protein. (1219 aa)
	T265_03239	Uncharacterized protein. (601 aa)
	T265_01957	Uncharacterized protein. (576 aa)
	T265_12739	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (929 aa)
	T265_04184	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (576 aa)
	T265_10014	Triosephosphate isomerase. (245 aa)
	T265_03274	Uncharacterized protein. (664 aa)
	T265_03115	Glutamine amidotransferase type-2 domain-containing protein. (2189 aa)
	T265_00471	Uncharacterized protein. (515 aa)
	T265_08191	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (1474 aa)
	T265_12819	Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (512 aa)
	T265_14299	Alpha-galactosidase. (468 aa)
	T265_15085	Pyruvate carboxyltransferase domain-containing protein. (322 aa)
	T265_10495	DRBM domain-containing protein. (501 aa)
	T265_09867	Uncharacterized protein. (361 aa)
	T265_11268	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (212 aa)
	T265_11980	Elp3 domain-containing protein. (371 aa)
	T265_01837	Uncharacterized protein. (285 aa)
	T265_06601	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (515 aa)
	T265_03273	Uncharacterized protein. (637 aa)
	T265_12933	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (760 aa)
	T265_10017	Triosephosphate isomerase. (252 aa)
	T265_10998	QRPTase_C domain-containing protein. (388 aa)
	T265_12938	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (394 aa)
	T265_10015	Triosephosphate isomerase. (241 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00471	T265_03239	A0A075A655	A0A074ZWL4	Uncharacterized protein.	Uncharacterized protein.	0.518
T265_00471	T265_06601	A0A075A655	A0A075ADH7	Uncharacterized protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.465
T265_00471	T265_14007	A0A075A655	A0A074ZGG1	Uncharacterized protein.	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	0.513
T265_00618	T265_11980	A0A075A5C8	A0A074YWL7	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Elp3 domain-containing protein.	0.439
T265_00618	T265_14007	A0A075A5C8	A0A074ZGG1	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	0.518
T265_01837	T265_04184	A0A075AIQ9	A0A075A0M6	Uncharacterized protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.904
T265_01837	T265_07976	A0A075AIQ9	A0A074ZFC7	Uncharacterized protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.904
T265_01837	T265_10014	A0A075AIQ9	A0A075A2Y2	Uncharacterized protein.	Triosephosphate isomerase.	0.890
T265_01837	T265_10015	A0A075AIQ9	A0A074ZET4	Uncharacterized protein.	Triosephosphate isomerase.	0.890
T265_01837	T265_10017	A0A075AIQ9	A0A074Z863	Uncharacterized protein.	Triosephosphate isomerase.	0.890
T265_01837	T265_11268	A0A075AIQ9	A0A074YZK3	Uncharacterized protein.	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.	0.954
T265_01837	T265_12933	A0A075AIQ9	A0A075AIH3	Uncharacterized protein.	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.	0.722
T265_01837	T265_12938	A0A075AIQ9	A0A075AIH6	Uncharacterized protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.904
T265_01957	T265_09867	A0A074ZWN2	A0A074Z4C7	Uncharacterized protein.	Uncharacterized protein.	0.488
T265_01957	T265_10495	A0A074ZWN2	A0A074Z6B5	Uncharacterized protein.	DRBM domain-containing protein.	0.413
T265_03115	T265_03273	A0A075A4J0	A0A075AHR2	Glutamine amidotransferase type-2 domain-containing protein.	Uncharacterized protein.	0.646
T265_03115	T265_03274	A0A075A4J0	A0A075A427	Glutamine amidotransferase type-2 domain-containing protein.	Uncharacterized protein.	0.646
T265_03115	T265_06601	A0A075A4J0	A0A075ADH7	Glutamine amidotransferase type-2 domain-containing protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.524
T265_03115	T265_15085	A0A075A4J0	A0A074Z7C1	Glutamine amidotransferase type-2 domain-containing protein.	Pyruvate carboxyltransferase domain-containing protein.	0.563
T265_03239	T265_00471	A0A074ZWL4	A0A075A655	Uncharacterized protein.	Uncharacterized protein.	0.518