(6 nodes) Mini-chromosome maintenance, conserved site network (Opisthorchis viverrini)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_00045	DNA helicase; Belongs to the MCM family. (807 aa)
	T265_13006	MCM domain-containing protein; Belongs to the MCM family. (691 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (767 aa)
	T265_13381	DNA helicase; Belongs to the MCM family. (889 aa)
	T265_07572	DNA helicase; Belongs to the MCM family. (885 aa)
	T265_08785	DNA helicase; Belongs to the MCM family. (810 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	T265_00045	A0A074ZT85	A0A075A3E8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	T265_07572	A0A074ZT85	A0A074ZC04	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	T265_08785	A0A074ZT85	A0A074Z7X2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	T265_13006	A0A074ZT85	A0A074ZVV6	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	MCM domain-containing protein; Belongs to the MCM family.	0.999
MCM7	T265_13381	A0A074ZT85	A0A074ZPI3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
T265_00045	MCM7	A0A075A3E8	A0A074ZT85	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
T265_00045	T265_07572	A0A075A3E8	A0A074ZC04	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
T265_00045	T265_08785	A0A075A3E8	A0A074Z7X2	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
T265_00045	T265_13006	A0A075A3E8	A0A074ZVV6	DNA helicase; Belongs to the MCM family.	MCM domain-containing protein; Belongs to the MCM family.	0.999
T265_00045	T265_13381	A0A075A3E8	A0A074ZPI3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
T265_07572	MCM7	A0A074ZC04	A0A074ZT85	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
T265_07572	T265_00045	A0A074ZC04	A0A075A3E8	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
T265_07572	T265_08785	A0A074ZC04	A0A074Z7X2	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
T265_07572	T265_13006	A0A074ZC04	A0A074ZVV6	DNA helicase; Belongs to the MCM family.	MCM domain-containing protein; Belongs to the MCM family.	0.999
T265_07572	T265_13381	A0A074ZC04	A0A074ZPI3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
T265_08785	MCM7	A0A074Z7X2	A0A074ZT85	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
T265_08785	T265_00045	A0A074Z7X2	A0A075A3E8	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
T265_08785	T265_07572	A0A074Z7X2	A0A074ZC04	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
T265_08785	T265_13006	A0A074Z7X2	A0A074ZVV6	DNA helicase; Belongs to the MCM family.	MCM domain-containing protein; Belongs to the MCM family.	0.999
T265_08785	T265_13381	A0A074Z7X2	A0A074ZPI3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999