(17 nodes) Translesion synthesis by POLK network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_07863	Ubiquitin-like domain-containing protein. (128 aa)
	T265_09518	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (650 aa)
	T265_11489	AAA domain-containing protein. (337 aa)
	T265_02109	Uncharacterized protein. (126 aa)
	T265_07360	Uncharacterized protein. (456 aa)
	T265_01429	AAA domain-containing protein. (1033 aa)
	T265_01639	DNA polymerase. (1998 aa)
	T265_02287	Uncharacterized protein. (1570 aa)
	T265_09593	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	T265_03367	Uncharacterized protein. (176 aa)
	T265_00470	Ubiquitin-like domain-containing protein. (197 aa)
	T265_01582	Uncharacterized protein. (533 aa)
	T265_02110	Replication factor C subunit 1. (1093 aa)
	T265_02897	UmuC domain-containing protein. (822 aa)
	T265_13304	AAA domain-containing protein. (339 aa)
	T265_13940	Uncharacterized protein. (2358 aa)
	T265_04851	Uncharacterized protein. (367 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00470	T265_01429	A0A075A368	A0A075A9X2	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.493
T265_00470	T265_01582	A0A075A368	A0A075A280	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.449
T265_00470	T265_02109	A0A075A368	A0A074ZXE1	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.526
T265_00470	T265_02110	A0A075A368	A0A075A0H7	Ubiquitin-like domain-containing protein.	Replication factor C subunit 1.	0.526
T265_00470	T265_02287	A0A075A368	A0A075A777	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.910
T265_00470	T265_02897	A0A075A368	A0A074ZUG3	Ubiquitin-like domain-containing protein.	UmuC domain-containing protein.	0.723
T265_00470	T265_03367	A0A075A368	A0A075A3G4	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.656
T265_00470	T265_04851	A0A075A368	A0A074ZLM1	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.675
T265_00470	T265_07360	A0A075A368	A0A075ABW4	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.996
T265_00470	T265_07863	A0A075A368	A0A074ZFT3	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.999
T265_00470	T265_09518	A0A075A368	A0A074Z9X4	Ubiquitin-like domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.568
T265_00470	T265_09593	A0A075A368	A0A075A4E0	Ubiquitin-like domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.958
T265_00470	T265_11489	A0A075A368	A0A074ZXA7	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.675
T265_00470	T265_13304	A0A075A368	A0A074ZVA6	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.675
T265_00470	T265_13940	A0A075A368	A0A074ZLZ3	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.675
T265_01429	T265_00470	A0A075A9X2	A0A075A368	AAA domain-containing protein.	Ubiquitin-like domain-containing protein.	0.493
T265_01429	T265_01582	A0A075A9X2	A0A075A280	AAA domain-containing protein.	Uncharacterized protein.	0.680
T265_01429	T265_01639	A0A075A9X2	A0A075A921	AAA domain-containing protein.	DNA polymerase.	0.702
T265_01429	T265_02109	A0A075A9X2	A0A074ZXE1	AAA domain-containing protein.	Uncharacterized protein.	0.515
T265_01429	T265_02110	A0A075A9X2	A0A075A0H7	AAA domain-containing protein.	Replication factor C subunit 1.	0.515