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| | EGR_08888 | DNA polymerase epsilon subunit 3. (125 aa) |
| | EGR_07517 | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (342 aa) |
| | EGR_00312 | DNA polymerase epsilon subunit 4. (160 aa) |
| | EGR_00851 | Cell cycle checkpoint protein RAD1. (299 aa) |
| | EGR_00438 | DNA replication complex GINS protein PSF1. (215 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (378 aa) |
| | EGR_04430 | DNA replication complex GINS protein PSF3. (244 aa) |
| | EGR_04009 | DNA repair protein complementing XP-A cells. (319 aa) |
| | EGR_04984 | CST complex subunit STN1. (400 aa) |
| | EGR_07019 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (434 aa) |
| | EGR_04874 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) |
| | EGR_07425 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (680 aa) |
| | EGR_10985 | Origin recognition complex subunit. (219 aa) |
| | EGR_10986 | Origin recognition complex subunit. (195 aa) |
| | EGR_09765 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (977 aa) |
| | EGR_09644 | DNA polymerase eta. (578 aa) |
| | EGR_09406 | Chromosome transmission fidelity protein. (107 aa) |
| | EGR_08768 | DNA polymerase epsilon subunit 2. (625 aa) |
| | EGR_08451 | Crossover junction endonuclease MUS81. (448 aa) |
| | EGR_08363 | Fanconi anemia group M protein. (934 aa) |
| | EGR_08104 | DNA mismatch repair protein Msh2. (324 aa) |
| | EGR_10895 | DNA replication licensing factor MCM9; Belongs to the MCM family. (961 aa) |
| | EGR_07878 | ATPase family AAA domain-containing protein 5. (818 aa) |
| | EGR_08102 | Transgelin; Belongs to the calponin family. (822 aa) |
| | EGR_07321 | DNA polymerase delta subunit 2. (487 aa) |
| | EGR_09122 | Origin recognition complex subunit. (199 aa) |
| | EGR_05978 | BRCA1-associated RING domain protein. (755 aa) |
| | EGR_06573 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (562 aa) |
| | EGR_08992 | DNA helicase; Belongs to the MCM family. (917 aa) |
| | EGR_06472 | Bloom syndrome protein. (1134 aa) |
| | EGR_05857 | Replication factor C subunit 5. (337 aa) |
| | EGR_05840 | Protein timeless. (1310 aa) |
| | EGR_05542 | Origin recognition complex subunit. (462 aa) |
| | EGR_08081 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (521 aa) |
| | EGR_05001 | DNA replication complex GINS protein SLD5. (677 aa) |
| | EGR_07816 | DNA polymerase epsilon catalytic subunit A. (2827 aa) |
| | EGR_04800 | Serine/threonine-protein kinase atr; Belongs to the PI3/PI4-kinase family. (2689 aa) |
| | EGR_04597 | Replication protein A. (262 aa) |
| | EGR_04444 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | EGR_07443 | Replication factor C subunit 1. (1128 aa) |
| | EGR_04149 | Uncharacterized protein. (289 aa) |
| | EGR_04044 | Replication factor C subunit 4. (391 aa) |
| | EGR_06987 | DNA polymerase. (1635 aa) |
| | EGR_03837 | MutS protein. (1064 aa) |
| | EGR_06673 | Nibrin. (626 aa) |
| | EGR_03228 | Uncharacterized protein. (1254 aa) |
| | EGR_03091 | 26S proteasome non-ATPase regulatory. (450 aa) |
| | EGR_03414 | Sister chromatid cohesion protein DCC1. (463 aa) |
| | EGR_03077 | DNA helicase; Belongs to the MCM family. (932 aa) |
| | EGR_02953 | PAX-interacting protein. (2074 aa) |
| | EGR_05920 | WD repeat and HMG-box DNA-binding protein. (1081 aa) |
| | EGR_05883 | DNA repair protein RAD51. (243 aa) |
| | EGR_05501 | DNA mismatch repair protein. (928 aa) |
| | EGR_02084 | DNA replication licensing factor MCM6; Belongs to the MCM family. (2678 aa) |
| | EGR_05343 | Replication factor C subunit 2. (345 aa) |
| | EGR_02052 | Checkpoint protein HUS1. (1022 aa) |
| | EGR_02057 | Cell cycle protein kinase spo4. (379 aa) |
| | EGR_02067 | Uncharacterized protein. (376 aa) |
| | EGR_01562 | DNA helicase; Belongs to the MCM family. (812 aa) |
| | EGR_09766 | ATP-dependent DNA helicase Q5. (498 aa) |
| | EGR_01488 | Uncharacterized protein. (1228 aa) |
| | EGR_01173 | DNA primase large subunit. (1057 aa) |
| | EGR_00889 | ATP-dependent DNA helicase Q4. (1132 aa) |
| | EGR_01877 | DNA polymerase alpha subunit B. (662 aa) |
| | EGR_01628 | DNA mismatch repair protein mutL. (217 aa) |
| | EGR_03712 | DNA repair endonuclease XPF. (1007 aa) |
| | EGR_00630 | Mismatch repair endonuclease PMS2. (719 aa) |
| | EGR_03596 | Cell cycle checkpoint protein RAD17. (618 aa) |
| | EGR_00528 | DNA topoisomerase 2-binding protein. (1313 aa) |
| | EGR_08323 | Origin recognition complex subunit. (219 aa) |
| | EGR_00364 | DNA repair protein RAD50. (1377 aa) |
| | EGR_03413 | Sister chromatid cohesion protein DCC1. (247 aa) |
| | EGR_00177 | DNA replication complex GINS protein PSF2. (424 aa) |
| | EGR_03230 | Origin recognition complex subunit. (526 aa) |
| | EGR_00247 | CDC45-related protein. (622 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (767 aa) |
| | EGR_02795 | Tumor suppressor p53-binding protein. (1108 aa) |
| | EGR_00030 | Claspin. (1011 aa) |
| | EGR_00175 | DNA polymerase. (1105 aa) |
| | EGR_02248 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (907 aa) |
| | EGR_00275 | Chromosome transmission fidelity protein. (857 aa) |
| | EGR_00370 | DNA replication licensing factor MCM8; Belongs to the MCM family. (1203 aa) |
| | EGR_01360 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (535 aa) |
| | EGR_01380 | DNA polymerase kappa. (672 aa) |
| | EGR_01385 | DNA repair protein RAD51. (417 aa) |
| | EGR_06086 | Exonuclease. (785 aa) |
| | EGR_01160 | Serine-protein kinase ATM; Belongs to the PI3/PI4-kinase family. (3794 aa) |
| | EGR_05700 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1093 aa) |
| | EGR_05513 | DNA helicase; Belongs to the MCM family. (753 aa) |
| | EGR_00376 | Serine/threonine-protein kinase. (512 aa) |
| | EGR_04934 | RecQ-mediated genome instability protein. (420 aa) |
| | EGR_03894 | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (387 aa) |
| | EGR_03355 | DNA ligase. (776 aa) |
| | EGR_02581 | Flap endonuclease GEN. (508 aa) |
| | EGR_02193 | DNA replication factor Cdt1. (601 aa) |
| | EGR_01676 | Replication factor C subunit 3. (338 aa) |
| | EGR_01292 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1191 aa) |
| | EGR_01432 | Cell cycle checkpoint control protein RAD9A. (456 aa) |
| | EGR_01072 | DNA polymerase alpha catalytic subunit. (2331 aa) |
| | EGR_01137 | MutS protein. (565 aa) |
