STRINGSTRING
EGR_07517 EGR_07517 EGR_08451 EGR_08451 EGR_08363 EGR_08363 EGR_06472 EGR_06472 EGR_05883 EGR_05883 EGR_00889 EGR_00889 EGR_01385 EGR_01385 EGR_06086 EGR_06086 EGR_05700 EGR_05700 EGR_04934 EGR_04934
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGR_07517DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (342 aa)
EGR_08451Crossover junction endonuclease MUS81. (448 aa)
EGR_08363Fanconi anemia group M protein. (934 aa)
EGR_06472Bloom syndrome protein. (1134 aa)
EGR_05883DNA repair protein RAD51. (243 aa)
EGR_00889ATP-dependent DNA helicase Q4. (1132 aa)
EGR_01385DNA repair protein RAD51. (417 aa)
EGR_06086Exonuclease. (785 aa)
EGR_05700DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1093 aa)
EGR_04934RecQ-mediated genome instability protein. (420 aa)
Your Current Organism:
Echinococcus granulosus
NCBI taxonomy Id: 6210
Other names: E. granulosus, Echinococcus granulosus G1 strain, Echinococcus granulosus G2 strain, Echinococcus granulosus G3 strain, Echinococcus granulosus Tasmanian sheep strain, Echinococcus granulosus buffalo strain, Echinococcus granulosus s. s., Echinococcus granulosus sensu stricto, Echinococcus granulosus sheep strain
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.