node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EGR_00889 | EGR_04934 | W6URI6 | W6V2P0 | ATP-dependent DNA helicase Q4. | RecQ-mediated genome instability protein. | 0.963 |
EGR_00889 | EGR_05700 | W6URI6 | W6V0X6 | ATP-dependent DNA helicase Q4. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.967 |
EGR_00889 | EGR_08363 | W6URI6 | W6U6G2 | ATP-dependent DNA helicase Q4. | Fanconi anemia group M protein. | 0.994 |
EGR_00889 | EGR_08451 | W6URI6 | W6U681 | ATP-dependent DNA helicase Q4. | Crossover junction endonuclease MUS81. | 0.942 |
EGR_04934 | EGR_00889 | W6V2P0 | W6URI6 | RecQ-mediated genome instability protein. | ATP-dependent DNA helicase Q4. | 0.963 |
EGR_04934 | EGR_05700 | W6V2P0 | W6V0X6 | RecQ-mediated genome instability protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.997 |
EGR_04934 | EGR_08363 | W6V2P0 | W6U6G2 | RecQ-mediated genome instability protein. | Fanconi anemia group M protein. | 0.994 |
EGR_04934 | EGR_08451 | W6V2P0 | W6U681 | RecQ-mediated genome instability protein. | Crossover junction endonuclease MUS81. | 0.948 |
EGR_05700 | EGR_00889 | W6V0X6 | W6URI6 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ATP-dependent DNA helicase Q4. | 0.967 |
EGR_05700 | EGR_04934 | W6V0X6 | W6V2P0 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | RecQ-mediated genome instability protein. | 0.997 |
EGR_05700 | EGR_08363 | W6V0X6 | W6U6G2 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Fanconi anemia group M protein. | 0.994 |
EGR_05700 | EGR_08451 | W6V0X6 | W6U681 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Crossover junction endonuclease MUS81. | 0.929 |
EGR_08363 | EGR_00889 | W6U6G2 | W6URI6 | Fanconi anemia group M protein. | ATP-dependent DNA helicase Q4. | 0.994 |
EGR_08363 | EGR_04934 | W6U6G2 | W6V2P0 | Fanconi anemia group M protein. | RecQ-mediated genome instability protein. | 0.994 |
EGR_08363 | EGR_05700 | W6U6G2 | W6V0X6 | Fanconi anemia group M protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.994 |
EGR_08363 | EGR_08451 | W6U6G2 | W6U681 | Fanconi anemia group M protein. | Crossover junction endonuclease MUS81. | 0.999 |
EGR_08451 | EGR_00889 | W6U681 | W6URI6 | Crossover junction endonuclease MUS81. | ATP-dependent DNA helicase Q4. | 0.942 |
EGR_08451 | EGR_04934 | W6U681 | W6V2P0 | Crossover junction endonuclease MUS81. | RecQ-mediated genome instability protein. | 0.948 |
EGR_08451 | EGR_05700 | W6U681 | W6V0X6 | Crossover junction endonuclease MUS81. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.929 |
EGR_08451 | EGR_08363 | W6U681 | W6U6G2 | Crossover junction endonuclease MUS81. | Fanconi anemia group M protein. | 0.999 |