STRINGSTRING
EGR_00883 EGR_00883 EGR_02614 EGR_02614 EGR_02743 EGR_02743 EGR_01146 EGR_01146 EGR_02434 EGR_02434 EGR_01743 EGR_01743 EGR_08566 EGR_08566 EGR_04216 EGR_04216 EGR_09984 EGR_09984 EGR_08304 EGR_08304 EGR_09164 EGR_09164 EGR_08965 EGR_08965 EGR_07769 EGR_07769 EGR_06710 EGR_06710 EGR_06386 EGR_06386 EGR_05919 EGR_05919 EGR_04836 EGR_04836 EGR_04176 EGR_04176 EGR_03059 EGR_03059 EGR_03003 EGR_03003 EGR_04581 EGR_04581 EGR_07948 EGR_07948 EGR_02899 EGR_02899 EGR_05823 EGR_05823 EGR_05619 EGR_05619 EGR_04442 EGR_04442 EGR_04127 EGR_04127 EGR_01392 EGR_01392
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGR_00883NADPH dependent diflavin oxidoreductase 1. (695 aa)
EGR_02614Glutaredoxin-related protein 5. (194 aa)
EGR_02743Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] (284 aa)
EGR_01146Iron-sulfur cluster assembly enzyme ISCU; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (159 aa)
EGR_02434Octanoyltransferase mitochondrial. (277 aa)
EGR_01743Iron-sulfur cluster assembly. (162 aa)
EGR_08566Transcription regulator; Belongs to the BolA/IbaG family. (82 aa)
EGR_04216Glutaredoxin 3. (210 aa)
EGR_09984LYR motif containing protein 4; Belongs to the complex I LYR family. (82 aa)
EGR_08304Adrenodoxin-like protein. (138 aa)
EGR_09164Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (745 aa)
EGR_08965Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. (117 aa)
EGR_07769Cysteine desulfurase. (436 aa)
EGR_06710MMS19 nucleotide excision repair protein. (1100 aa)
EGR_06386CDGSH iron sulfur domain-containing protein. (117 aa)
EGR_05919BolA-like protein 1; Belongs to the BolA/IbaG family. (129 aa)
EGR_04836Putative transferase. (656 aa)
EGR_04176Cytosolic Fe-S cluster assembly factor NUBP2. (411 aa)
EGR_03059Iron-sulfur cluster assembly. (922 aa)
EGR_03003Maf-like protein. (258 aa)
EGR_04581NFU1 iron-sulfur cluster scaffold. (191 aa)
EGR_07948Frataxin. (178 aa)
EGR_02899Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (495 aa)
EGR_05823Cytosolic Fe-S cluster assembly factor nubp1-A. (378 aa)
EGR_05619DUF1713 domain-containing protein. (301 aa)
EGR_04442Co-chaperone protein hscB. (283 aa)
EGR_04127Cytosolic Fe-S cluster assembly factor NARFL; Belongs to the NARF family. (582 aa)
EGR_01392Lipoyltransferase. (425 aa)
Your Current Organism:
Echinococcus granulosus
NCBI taxonomy Id: 6210
Other names: E. granulosus, Echinococcus granulosus G1 strain, Echinococcus granulosus G2 strain, Echinococcus granulosus G3 strain, Echinococcus granulosus Tasmanian sheep strain, Echinococcus granulosus buffalo strain, Echinococcus granulosus s. s., Echinococcus granulosus sensu stricto, Echinococcus granulosus sheep strain
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