STRINGSTRING
EGR_07517 EGR_07517 EGR_00833 EGR_00833 EGR_07425 EGR_07425 EGR_09762 EGR_09762 EGR_09765 EGR_09765 EGR_08451 EGR_08451 EGR_08363 EGR_08363 EGR_10895 EGR_10895 EGR_07761 EGR_07761 EGR_08117 EGR_08117 EGR_07955 EGR_07955 EGR_07307 EGR_07307 EGR_06722 EGR_06722 EGR_08992 EGR_08992 EGR_06472 EGR_06472 EGR_05825 EGR_05825 EGR_08118 EGR_08118 EGR_04599 EGR_04599 EGR_05001 EGR_05001 EGR_04444 EGR_04444 EGR_04509 EGR_04509 EGR_04149 EGR_04149 EGR_03821 EGR_03821 EGR_06987 EGR_06987 EGR_06744 EGR_06744 EGR_03555 EGR_03555 EGR_06673 EGR_06673 EGR_03067 EGR_03067 EGR_03077 EGR_03077 EGR_05883 EGR_05883 EGR_02084 EGR_02084 EGR_02052 EGR_02052 EGR_02057 EGR_02057 EGR_02067 EGR_02067 EGR_01562 EGR_01562 EGR_09766 EGR_09766 EGR_00889 EGR_00889 EGR_01618 EGR_01618 EGR_00727 EGR_00727 EGR_03712 EGR_03712 EGR_03461 EGR_03461 EGR_00658 EGR_00658 EGR_00177 EGR_00177 EGR_00247 EGR_00247 MCM7 MCM7 EGR_00370 EGR_00370 EGR_01385 EGR_01385 EGR_05700 EGR_05700 EGR_05513 EGR_05513 EGR_04210 EGR_04210 EGR_02581 EGR_02581 EGR_00659 EGR_00659
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGR_07517DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (342 aa)
EGR_00833Serine/threonine-protein phosphatase. (307 aa)
EGR_07425Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (680 aa)
EGR_09762Breast cancer type 1 susceptibility protein. (167 aa)
EGR_09765ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (977 aa)
EGR_08451Crossover junction endonuclease MUS81. (448 aa)
EGR_08363Fanconi anemia group M protein. (934 aa)
EGR_10895DNA replication licensing factor MCM9; Belongs to the MCM family. (961 aa)
EGR_07761SOSS complex subunit B1. (139 aa)
EGR_08117Nipped-B protein. (2498 aa)
EGR_07955DNA repair and recombination protein RAD54B. (420 aa)
EGR_07307Putative DNA helicase Ino80. (1230 aa)
EGR_06722SAM domain and HD domain-containing protein. (561 aa)
EGR_08992DNA helicase; Belongs to the MCM family. (917 aa)
EGR_06472Bloom syndrome protein. (1134 aa)
EGR_05825Nipped-B protein. (2548 aa)
EGR_08118Nipped-B-like protein. (809 aa)
EGR_04599Double-strand-break repair protein Rad. (806 aa)
EGR_05001DNA replication complex GINS protein SLD5. (677 aa)
EGR_04444Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
EGR_04509Meiotic recombination protein REC8. (565 aa)
EGR_04149Uncharacterized protein. (289 aa)
EGR_03821Uncharacterized protein. (89 aa)
EGR_06987DNA polymerase. (1635 aa)
EGR_06744DNA repair and recombination protein RAD54-like protein. (596 aa)
EGR_03555Uncharacterized protein. (853 aa)
EGR_06673Nibrin. (626 aa)
EGR_03067Helicase domino. (2266 aa)
EGR_03077DNA helicase; Belongs to the MCM family. (932 aa)
EGR_05883DNA repair protein RAD51. (243 aa)
EGR_02084DNA replication licensing factor MCM6; Belongs to the MCM family. (2678 aa)
EGR_02052Checkpoint protein HUS1. (1022 aa)
EGR_02057Cell cycle protein kinase spo4. (379 aa)
EGR_02067Uncharacterized protein. (376 aa)
EGR_01562DNA helicase; Belongs to the MCM family. (812 aa)
EGR_09766ATP-dependent DNA helicase Q5. (498 aa)
EGR_00889ATP-dependent DNA helicase Q4. (1132 aa)
EGR_01618ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (638 aa)
EGR_00727DNA repair protein XRCC1. (807 aa)
EGR_03712DNA repair endonuclease XPF. (1007 aa)
EGR_03461RING finger and WD repeat domain-containing protein 3. (613 aa)
EGR_00658WD repeat-containing protein. (261 aa)
EGR_00177DNA replication complex GINS protein PSF2. (424 aa)
EGR_00247CDC45-related protein. (622 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (767 aa)
EGR_00370DNA replication licensing factor MCM8; Belongs to the MCM family. (1203 aa)
EGR_01385DNA repair protein RAD51. (417 aa)
EGR_05700DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1093 aa)
EGR_05513DNA helicase; Belongs to the MCM family. (753 aa)
EGR_04210NF-kappa-B inhibitor-like protein 2. (1555 aa)
EGR_02581Flap endonuclease GEN. (508 aa)
EGR_00659WD repeat-containing protein. (230 aa)
Your Current Organism:
Echinococcus granulosus
NCBI taxonomy Id: 6210
Other names: E. granulosus, Echinococcus granulosus G1 strain, Echinococcus granulosus G2 strain, Echinococcus granulosus G3 strain, Echinococcus granulosus Tasmanian sheep strain, Echinococcus granulosus buffalo strain, Echinococcus granulosus s. s., Echinococcus granulosus sensu stricto, Echinococcus granulosus sheep strain
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