STRINGSTRING
EGR_00528 EGR_00528 EGR_00961 EGR_00961 EGR_07425 EGR_07425 EGR_08451 EGR_08451 EGR_06214 EGR_06214 EGR_06573 EGR_06573 EGR_05799 EGR_05799 EGR_05450 EGR_05450 EGR_03750 EGR_03750 EGR_06673 EGR_06673 EGR_02602 EGR_02602 EGR_02052 EGR_02052 EGR_03596 EGR_03596 EGR_03461 EGR_03461 EGR_00030 EGR_00030 EGR_01360 EGR_01360 EGR_01160 EGR_01160 EGR_00376 EGR_00376 EGR_03894 EGR_03894 EGR_03749 EGR_03749 EGR_01432 EGR_01432
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGR_00528DNA topoisomerase 2-binding protein. (1313 aa)
EGR_00961Zinc finger protein 830. (228 aa)
EGR_07425Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (680 aa)
EGR_08451Crossover junction endonuclease MUS81. (448 aa)
EGR_06214DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (4075 aa)
EGR_06573Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (562 aa)
EGR_05799RAD50-interacting protein. (938 aa)
EGR_05450Fanconi anemia group D2 protein. (1892 aa)
EGR_03750Denticleless protein. (578 aa)
EGR_06673Nibrin. (626 aa)
EGR_02602WW domain-containing adapter protein with coiled-coil. (736 aa)
EGR_02052Checkpoint protein HUS1. (1022 aa)
EGR_03596Cell cycle checkpoint protein RAD17. (618 aa)
EGR_03461RING finger and WD repeat domain-containing protein 3. (613 aa)
EGR_00030Claspin. (1011 aa)
EGR_01360Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (535 aa)
EGR_01160Serine-protein kinase ATM; Belongs to the PI3/PI4-kinase family. (3794 aa)
EGR_00376Serine/threonine-protein kinase. (512 aa)
EGR_03894TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (387 aa)
EGR_03749Uncharacterized protein. (204 aa)
EGR_01432Cell cycle checkpoint control protein RAD9A. (456 aa)
Your Current Organism:
Echinococcus granulosus
NCBI taxonomy Id: 6210
Other names: E. granulosus, Echinococcus granulosus G1 strain, Echinococcus granulosus G2 strain, Echinococcus granulosus G3 strain, Echinococcus granulosus Tasmanian sheep strain, Echinococcus granulosus buffalo strain, Echinococcus granulosus s. s., Echinococcus granulosus sensu stricto, Echinococcus granulosus sheep strain
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