STRINGSTRING
EGR_04231 EGR_04231 EGR_00549 EGR_00549 EGR_00203 EGR_00203 MCM7 MCM7 EGR_00247 EGR_00247 EGR_00364 EGR_00364 EGR_03616 EGR_03616 EGR_03581 EGR_03581 EGR_01618 EGR_01618 EGR_00889 EGR_00889 EGR_00275 EGR_00275 EGR_01471 EGR_01471 EGR_01690 EGR_01690 EGR_01585 EGR_01585 EGR_09766 EGR_09766 EGR_02447 EGR_02447 EGR_01562 EGR_01562 EGR_02132 EGR_02132 EGR_01954 EGR_01954 EGR_02084 EGR_02084 EGR_03077 EGR_03077 EGR_03500 EGR_03500 EGR_06673 EGR_06673 EGR_04476 EGR_04476 EGR_04444 EGR_04444 EGR_04351 EGR_04351 EGR_05001 EGR_05001 EGR_04559 EGR_04559 EGR_05500 EGR_05500 EGR_05216 EGR_05216 EGR_05805 EGR_05805 EGR_05727 EGR_05727 EGR_06472 EGR_06472 EGR_06524 EGR_06524 EGR_08992 EGR_08992 EGR_07672 EGR_07672 EGR_10895 EGR_10895 EGR_08368 EGR_08368 EGR_08363 EGR_08363 EGR_09406 EGR_09406 EGR_09765 EGR_09765 EGR_04430 EGR_04430 EGR_02421 EGR_02421 EGR_01542 EGR_01542 EGR_07517 EGR_07517 EGR_00370 EGR_00370 EGR_06061 EGR_06061 EGR_05700 EGR_05700 EGR_05513 EGR_05513 EGR_04548 EGR_04548 EGR_03785 EGR_03785 EGR_02133 EGR_02133 EGR_01676 EGR_01676
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGR_04231ATP-dependent DNA helicase 2 subunit 2. (462 aa)
EGR_00549TFIIH basal transcription factor complex helicase subunit. (1180 aa)
EGR_00203ATP-dependent DNA helicase; Belongs to the helicase family. (677 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (767 aa)
EGR_00247CDC45-related protein. (622 aa)
EGR_00364DNA repair protein RAD50. (1377 aa)
EGR_03616DNA excision repair protein ERCC-6-like protein. (1195 aa)
EGR_03581DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (651 aa)
EGR_01618ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (638 aa)
EGR_00889ATP-dependent DNA helicase Q4. (1132 aa)
EGR_00275Chromosome transmission fidelity protein. (857 aa)
EGR_01471ATP-dependent DNA helicase 2 subunit. (227 aa)
EGR_01690Transcriptional regulator ATRX. (1866 aa)
EGR_01585Putative ATP-dependent RNA helicase DDX11-like protein. (992 aa)
EGR_09766ATP-dependent DNA helicase Q5. (498 aa)
EGR_02447ATP-dependent RNA helicase Ddx1. (453 aa)
EGR_01562DNA helicase; Belongs to the MCM family. (812 aa)
EGR_02132Fanconi anemia group J protein. (586 aa)
EGR_01954Regulator of telomere elongation helicase. (1125 aa)
EGR_02084DNA replication licensing factor MCM6; Belongs to the MCM family. (2678 aa)
EGR_03077DNA helicase; Belongs to the MCM family. (932 aa)
EGR_03500Activating signal cointegrator 1 complex subunit. (2267 aa)
EGR_06673Nibrin. (626 aa)
EGR_04476DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (896 aa)
EGR_04444Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
EGR_04351annotation not available (1870 aa)
EGR_05001DNA replication complex GINS protein SLD5. (677 aa)
EGR_04559DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1652 aa)
EGR_05500Chromodomain-helicase-DNA-binding protein. (1909 aa)
EGR_05216RuvB-like helicase; Belongs to the RuvB family. (472 aa)
EGR_05805Protection of telomeres protein. (517 aa)
EGR_05727Regulator of nonsense transcripts. (1433 aa)
EGR_06472Bloom syndrome protein. (1134 aa)
EGR_06524ATP-dependent RNA helicase DDX1. (1094 aa)
EGR_08992DNA helicase; Belongs to the MCM family. (917 aa)
EGR_07672Chromodomain-helicase-DNA-binding protein. (3093 aa)
EGR_10895DNA replication licensing factor MCM9; Belongs to the MCM family. (961 aa)
EGR_08368Twinkle protein. (327 aa)
EGR_08363Fanconi anemia group M protein. (934 aa)
EGR_09406Chromosome transmission fidelity protein. (107 aa)
EGR_09765ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (977 aa)
EGR_04430DNA replication complex GINS protein PSF3. (244 aa)
EGR_02421General transcription factor IIF polypeptide 2. (310 aa)
EGR_01542RuvB-like helicase; Belongs to the RuvB family. (456 aa)
EGR_07517DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (342 aa)
EGR_00370DNA replication licensing factor MCM8; Belongs to the MCM family. (1203 aa)
EGR_06061ATP-dependent RNA helicase A. (1670 aa)
EGR_05700DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1093 aa)
EGR_05513DNA helicase; Belongs to the MCM family. (753 aa)
EGR_04548TFIIH basal transcription factor complex helicase XPB subunit. (886 aa)
EGR_03785Putative ATP-dependent DNA helicase HFM1. (1370 aa)
EGR_02133Fanconi anemia group J protein. (117 aa)
EGR_01676Replication factor C subunit 3. (338 aa)
Your Current Organism:
Echinococcus granulosus
NCBI taxonomy Id: 6210
Other names: E. granulosus, Echinococcus granulosus G1 strain, Echinococcus granulosus G2 strain, Echinococcus granulosus G3 strain, Echinococcus granulosus Tasmanian sheep strain, Echinococcus granulosus buffalo strain, Echinococcus granulosus s. s., Echinococcus granulosus sensu stricto, Echinococcus granulosus sheep strain
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