STRINGSTRING
EGR_06414 EGR_06414 EGR_07376 EGR_07376 EGR_06985 EGR_06985 EGR_07918 EGR_07918 EGR_07155 EGR_07155 EGR_07193 EGR_07193 EGR_08132 EGR_08132 EGR_07826 EGR_07826 EGR_08337 EGR_08337 EGR_08381 EGR_08381 EGR_09399 EGR_09399 EGR_08917 EGR_08917 EGR_05580 EGR_05580 EGR_04725 EGR_04725 EGR_04795 EGR_04795 EGR_04422 EGR_04422 EGR_04197 EGR_04197 EGR_06448 EGR_06448 EGR_10921 EGR_10921 EGR_03384 EGR_03384 EGR_03226 EGR_03226 EGR_03029 EGR_03029 EGR_05791 EGR_05791 EGR_02821 EGR_02821 EGR_05627 EGR_05627 EGR_02414 EGR_02414 EGR_05035 EGR_05035 EGR_02392 EGR_02392 EGR_02512 EGR_02512 EGR_00550 EGR_00550 EGR_03145 EGR_03145 EGR_08018 EGR_08018 EGR_00305 EGR_00305 EGR_00330 EGR_00330 EGR_06874 EGR_06874 EGR_00201 EGR_00201 EGR_03879 EGR_03879 EGR_03227 EGR_03227 EGR_03130 EGR_03130 EGR_02420 EGR_02420 EGR_01631 EGR_01631 EGR_05783 EGR_05783 EGR_08144 EGR_08144 EGR_10065 EGR_10065 EGR_07612 EGR_07612 EGR_09524 EGR_09524 EGR_07791 EGR_07791 EGR_04178 EGR_04178 EGR_01111 EGR_01111 EGR_03928 EGR_03928 EGR_02396 EGR_02396 EGR_01194 EGR_01194 EGR_02045 EGR_02045 EGR_06449 EGR_06449 EGR_01657 EGR_01657 EGR_05612 EGR_05612 EGR_06040 EGR_06040 EGR_06267 EGR_06267
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGR_06414Protein transport protein Sec24C. (1008 aa)
EGR_07376GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (952 aa)
EGR_06985WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (841 aa)
EGR_07918Protein transport protein Sec24B. (583 aa)
EGR_07155Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
EGR_07193Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (106 aa)
EGR_08132Cysteine protease ATG4C. (1445 aa)
EGR_07826Tumor susceptibility gene 101 protein. (1029 aa)
EGR_08337AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (552 aa)
EGR_08381Mitochondrial import inner membrane translocase subunit tim9. (84 aa)
EGR_09399ER lumen protein-retaining receptor. (269 aa)
EGR_08917Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (160 aa)
EGR_05580ER lumen protein-retaining receptor. (454 aa)
EGR_04725Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (351 aa)
EGR_04795Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (475 aa)
EGR_04422AP-1 complex subunit gamma-1. (921 aa)
EGR_04197Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (938 aa)
EGR_06448AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (970 aa)
EGR_10921Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (196 aa)
EGR_03384AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (389 aa)
EGR_03226Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (378 aa)
EGR_03029Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. (671 aa)
EGR_05791Importin subunit alpha; Belongs to the importin alpha family. (525 aa)
EGR_02821Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (198 aa)
EGR_05627AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (168 aa)
EGR_02414Nucleoporin seh1; Belongs to the WD repeat SEC13 family. (489 aa)
EGR_05035Nucleoporin NUP53. (1249 aa)
EGR_02392AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (439 aa)
EGR_02512Nuclear pore protein. (944 aa)
EGR_00550Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (231 aa)
EGR_03145Vacuolar protein sorting-associated protein 37B. (192 aa)
EGR_08018AP-3 complex subunit beta-1. (982 aa)
EGR_00305Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (236 aa)
EGR_00330Coatomer subunit beta. (1646 aa)
EGR_06874Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (150 aa)
EGR_00201Protein transport protein Sec61 subunit alpha-like protein. (1005 aa)
EGR_03879Mitochondrial import inner membrane translocase subunit Tim10. (90 aa)
EGR_03227Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (392 aa)
EGR_03130Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (509 aa)
EGR_02420Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (1117 aa)
EGR_01631Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (1051 aa)
EGR_05783AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
EGR_08144GTP-binding protein SAR1b; Belongs to the small GTPase superfamily. SAR1 family. (199 aa)
EGR_10065Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (552 aa)
EGR_07612Mitochondrial import inner membrane translocase subunit Tim13; Belongs to the small Tim family. (96 aa)
EGR_09524AP-3 complex subunit sigma-2. (194 aa)
EGR_07791Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. (231 aa)
EGR_04178GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (215 aa)
EGR_01111Importin subunit alpha; Belongs to the importin alpha family. (530 aa)
EGR_03928Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (771 aa)
EGR_02396Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (246 aa)
EGR_01194Autophagy-related protein 3. (339 aa)
EGR_02045Golgi SNAP receptor complex member; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (226 aa)
EGR_06449Mitochondrial import inner membrane translocase subunit tim-8; Belongs to the small Tim family. (106 aa)
EGR_01657Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (911 aa)
EGR_05612AP-3 complex subunit sigma-1. (232 aa)
EGR_06040AP complex subunit beta. (1009 aa)
EGR_06267AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family. (1103 aa)
Your Current Organism:
Echinococcus granulosus
NCBI taxonomy Id: 6210
Other names: E. granulosus, Echinococcus granulosus G1 strain, Echinococcus granulosus G2 strain, Echinococcus granulosus G3 strain, Echinococcus granulosus Tasmanian sheep strain, Echinococcus granulosus buffalo strain, Echinococcus granulosus s. s., Echinococcus granulosus sensu stricto, Echinococcus granulosus sheep strain
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.