(18 nodes) PLC beta mediated events network (Echinococcus granulosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EGR_00342	cAMP-dependent protein kinase type II regulatory subunit. (367 aa)
	EGR_02728	cAMP-dependent protein kinase regulatory subunit. (451 aa)
	EGR_08046	Ca(2+)/calmodulin-responsive adenylate cyclase. (2210 aa)
	EGR_04421	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (366 aa)
	EGR_07518	Neurobeachin. (2981 aa)
	EGR_04260	ARF GTPase-activating protein GIT2. (289 aa)
	EGR_06877	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (370 aa)
	EGR_06039	cAMP-dependent protein kinase catalytic subunit. (1334 aa)
	EGR_10356	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family. (372 aa)
	EGR_01141	Adenylate cyclase type. (1128 aa)
	EGR_08422	CBL-interacting protein kinase. (250 aa)
	EGR_08246	Guanine nucleotide-binding protein G(Q) subunit alpha. (582 aa)
	EGR_00820	cAMP-dependent protein kinase type II regulatory subunit. (379 aa)
	EGR_00105	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1310 aa)
	EGR_06851	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (390 aa)
	EGR_02083	Phosphodiesterase. (448 aa)
	EGR_01447	Adenylate cyclase type 9. (2296 aa)
	EGR_00868	Adenylate cyclase type. (1140 aa)

Your Current Organism:

Echinococcus granulosus

NCBI taxonomy Id: 6210
Other names: E. granulosus, Echinococcus granulosus G1 strain, Echinococcus granulosus G2 strain, Echinococcus granulosus G3 strain, Echinococcus granulosus Tasmanian sheep strain, Echinococcus granulosus buffalo strain, Echinococcus granulosus s. s., Echinococcus granulosus sensu stricto, Echinococcus granulosus sheep strain

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGR_00105	EGR_08246	W6UW42	W6UU29	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Guanine nucleotide-binding protein G(Q) subunit alpha.	0.915
EGR_00342	EGR_00868	U6IUI1	W6VBU8	cAMP-dependent protein kinase type II regulatory subunit.	Adenylate cyclase type.	0.487
EGR_00342	EGR_01141	U6IUI1	W6URZ1	cAMP-dependent protein kinase type II regulatory subunit.	Adenylate cyclase type.	0.437
EGR_00342	EGR_01447	U6IUI1	W6VAL1	cAMP-dependent protein kinase type II regulatory subunit.	Adenylate cyclase type 9.	0.487
EGR_00342	EGR_04260	U6IUI1	W6UI97	cAMP-dependent protein kinase type II regulatory subunit.	ARF GTPase-activating protein GIT2.	0.478
EGR_00342	EGR_04421	U6IUI1	W6UGX7	cAMP-dependent protein kinase type II regulatory subunit.	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.984
EGR_00342	EGR_06039	U6IUI1	W6ULN1	cAMP-dependent protein kinase type II regulatory subunit.	cAMP-dependent protein kinase catalytic subunit.	0.725
EGR_00342	EGR_06851	U6IUI1	W6UXN2	cAMP-dependent protein kinase type II regulatory subunit.	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.981
EGR_00342	EGR_06877	U6IUI1	W6UJC6	cAMP-dependent protein kinase type II regulatory subunit.	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.984
EGR_00342	EGR_08046	U6IUI1	W6U790	cAMP-dependent protein kinase type II regulatory subunit.	Ca(2+)/calmodulin-responsive adenylate cyclase.	0.478
EGR_00820	EGR_00868	W6UUD1	W6VBU8	cAMP-dependent protein kinase type II regulatory subunit.	Adenylate cyclase type.	0.437
EGR_00820	EGR_01141	W6UUD1	W6URZ1	cAMP-dependent protein kinase type II regulatory subunit.	Adenylate cyclase type.	0.437
EGR_00820	EGR_01447	W6UUD1	W6VAL1	cAMP-dependent protein kinase type II regulatory subunit.	Adenylate cyclase type 9.	0.437
EGR_00820	EGR_04260	W6UUD1	W6UI97	cAMP-dependent protein kinase type II regulatory subunit.	ARF GTPase-activating protein GIT2.	0.478
EGR_00820	EGR_04421	W6UUD1	W6UGX7	cAMP-dependent protein kinase type II regulatory subunit.	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.959
EGR_00820	EGR_06039	W6UUD1	W6ULN1	cAMP-dependent protein kinase type II regulatory subunit.	cAMP-dependent protein kinase catalytic subunit.	0.725
EGR_00820	EGR_06851	W6UUD1	W6UXN2	cAMP-dependent protein kinase type II regulatory subunit.	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.951
EGR_00820	EGR_06877	W6UUD1	W6UJC6	cAMP-dependent protein kinase type II regulatory subunit.	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.953
EGR_00820	EGR_08046	W6UUD1	W6U790	cAMP-dependent protein kinase type II regulatory subunit.	Ca(2+)/calmodulin-responsive adenylate cyclase.	0.478
EGR_00868	EGR_00342	W6VBU8	U6IUI1	Adenylate cyclase type.	cAMP-dependent protein kinase type II regulatory subunit.	0.487

page 1 of 5

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About