29 items (Anopheles funestus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

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Your Input:
	A0A182R4R2	Uncharacterized protein; Belongs to the 5'-nucleotidase family. (587 aa)
	A0A182R6W6	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. Belongs to the adenylate kinase family. AK6 subfamily. (174 aa)
	A0A182R7J2	Amidophosphoribosyltransferase. (545 aa)
	A0A182R7N9	PfkB domain-containing protein. (383 aa)
	A0A182R7P1	Uncharacterized protein. (684 aa)
	A0A182R802	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (466 aa)
	Adk2	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (240 aa)
	A0A182RBG7	Uncharacterized protein; Belongs to the 5'-nucleotidase family. (612 aa)
	A0A182RDQ6	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (188 aa)
	A0A182RGK6	PfkB domain-containing protein. (349 aa)
	A0A182RLV4	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (302 aa)
	A0A182RQ07	MGS domain-containing protein. (590 aa)
	A0A182RQ99	Uncharacterized protein. (1077 aa)
	A0A182RSD7	Uncharacterized protein. (432 aa)
	A0A182RW44	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (512 aa)
	A0A182RYG0	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
	A0A4Y0AWS2	Uncharacterized protein. (619 aa)
	A0A4Y0BFN9	Uncharacterized protein. (536 aa)
	A0A4Y0BHK2	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (772 aa)
	A0A4Y0BJE9	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (800 aa)
	A0A4Y0BK14	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (782 aa)
	A0A4Y0BL20	Phosphodiesterase. (1140 aa)
	A0A4Y0BM02	Phosphodiesterase. (702 aa)
	A0A4Y0BM50	Uncharacterized protein; Belongs to the 5'-nucleotidase family. (556 aa)
	A0A4Y0BNG4	Uncharacterized protein; Belongs to the adenylate kinase family. (244 aa)
	A0A4Y0BQ31	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1382 aa)
	A0A4Y0BTR6	Uncharacterized protein; Belongs to the adenylate kinase family. (199 aa)
	A0A4Y0BUT5	Pribosyltran domain-containing protein. (187 aa)
	A0A4Y0BV17	Uncharacterized protein. (213 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A182R4R2	A0A182R6W6	A0A182R4R2	A0A182R6W6	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. Belongs to the adenylate kinase family. AK6 subfamily.	0.914
A0A182R4R2	A0A182R7N9	A0A182R4R2	A0A182R7N9	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	PfkB domain-containing protein.	0.923
A0A182R4R2	A0A182R7P1	A0A182R4R2	A0A182R7P1	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uncharacterized protein.	0.919
A0A182R4R2	A0A182R802	A0A182R4R2	A0A182R802	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.930
A0A182R4R2	A0A182RBG7	A0A182R4R2	A0A182RBG7	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	0.930
A0A182R4R2	A0A182RDQ6	A0A182R4R2	A0A182RDQ6	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.914
A0A182R4R2	A0A182RGK6	A0A182R4R2	A0A182RGK6	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	PfkB domain-containing protein.	0.923
A0A182R4R2	A0A182RLV4	A0A182R4R2	A0A182RLV4	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family.	0.903
A0A182R4R2	A0A182RQ07	A0A182R4R2	A0A182RQ07	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	MGS domain-containing protein.	0.927
A0A182R4R2	A0A182RQ99	A0A182R4R2	A0A182RQ99	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uncharacterized protein.	0.703
A0A182R4R2	A0A182RSD7	A0A182R4R2	A0A182RSD7	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uncharacterized protein.	0.957
A0A182R4R2	A0A182RW44	A0A182R4R2	A0A182RW44	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.923
A0A182R4R2	A0A182RYG0	A0A182R4R2	A0A182RYG0	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.928
A0A182R4R2	A0A4Y0AWS2	A0A182R4R2	A0A4Y0AWS2	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uncharacterized protein.	0.885
A0A182R4R2	A0A4Y0BFN9	A0A182R4R2	A0A4Y0BFN9	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uncharacterized protein.	0.910
A0A182R4R2	A0A4Y0BHK2	A0A182R4R2	A0A4Y0BHK2	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.885
A0A182R4R2	A0A4Y0BJE9	A0A182R4R2	A0A4Y0BJE9	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.908
A0A182R4R2	A0A4Y0BK14	A0A182R4R2	A0A4Y0BK14	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.885
A0A182R4R2	A0A4Y0BL20	A0A182R4R2	A0A4Y0BL20	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Phosphodiesterase.	0.910
A0A182R4R2	A0A4Y0BM02	A0A182R4R2	A0A4Y0BM02	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Phosphodiesterase.	0.914