(93 nodes) Regulation of small GTPase mediated signal transduction, and Small GTPase network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182R1H2	Uncharacterized protein. (184 aa)
	A0A182R1K6	Uncharacterized protein. (1823 aa)
	A0A182R4B1	Rho-GAP domain-containing protein. (690 aa)
	A0A182R4B7	Uncharacterized protein. (533 aa)
	A0A182R656	Uncharacterized protein. (195 aa)
	A0A182R7A5	Uncharacterized protein. (273 aa)
	A0A182R8V6	Rho-GAP domain-containing protein. (1087 aa)
	A0A182RAI9	Uncharacterized protein. (200 aa)
	A0A182RB14	Uncharacterized protein. (1347 aa)
	A0A182RB32	Uncharacterized protein. (1676 aa)
	A0A182RBE8	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (524 aa)
	A0A182RC06	Uncharacterized protein. (192 aa)
	A0A182REJ9	Uncharacterized protein. (856 aa)
	A0A182REK6	Uncharacterized protein. (2338 aa)
	A0A182RGP4	Uncharacterized protein. (1121 aa)
	A0A182RH59	Uncharacterized protein. (981 aa)
	A0A182RHF1	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	A0A182RI03	Rho-GAP domain-containing protein. (340 aa)
	A0A182RJF3	Uncharacterized protein. (700 aa)
	A0A182RJG6	Uncharacterized protein. (721 aa)
	A0A182RJK1	Uncharacterized protein. (1884 aa)
	A0A182RJW0	Uncharacterized protein. (1576 aa)
	A0A182RKX5	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1412 aa)
	A0A182RLM4	Uncharacterized protein. (278 aa)
	A0A182RPH1	DH domain-containing protein. (968 aa)
	A0A182RR36	BTB domain-containing protein. (723 aa)
	A0A182RRK1	Uncharacterized protein. (1841 aa)
	A0A182RT13	Uncharacterized protein. (948 aa)
	A0A182RTJ3	PH domain-containing protein. (555 aa)
	A0A182RTZ5	Uncharacterized protein. (497 aa)
	A0A182RUM2	Protein kinase domain-containing protein. (532 aa)
	A0A182RV76	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	A0A182RX97	Uncharacterized protein. (327 aa)
	A0A182RXF5	Uncharacterized protein. (1417 aa)
	A0A182RYW6	Non-specific serine/threonine protein kinase. (869 aa)
	A0A182S528	Uncharacterized protein. (376 aa)
	A0A2Y9D1P9	Uncharacterized protein. (1287 aa)
	A0A2Y9D1W5	Uncharacterized protein. (2547 aa)
	A0A4Y0ARZ1	Uncharacterized protein. (1457 aa)
	A0A4Y0AUP8	Uncharacterized protein. (756 aa)
	A0A4Y0AUQ3	Uncharacterized protein. (1351 aa)
	A0A4Y0AYG8	Uncharacterized protein. (1809 aa)
	A0A4Y0AYI1	Uncharacterized protein. (1443 aa)
	A0A4Y0B648	Uncharacterized protein. (1817 aa)
	A0A4Y0B7J2	Uncharacterized protein. (1411 aa)
	A0A4Y0BE67	Uncharacterized protein. (2575 aa)
	A0A4Y0BFP5	Uncharacterized protein. (78 aa)
	A0A4Y0BFY0	Uncharacterized protein. (1279 aa)
	A0A4Y0BGE4	Uncharacterized protein. (939 aa)
	A0A4Y0BGQ7	Uncharacterized protein. (69 aa)
	A0A4Y0BH18	Non-specific serine/threonine protein kinase. (686 aa)
	A0A4Y0BH21	Uncharacterized protein. (4052 aa)
	A0A4Y0BI08	Uncharacterized protein. (865 aa)
	A0A4Y0BI89	Uncharacterized protein. (1194 aa)
	A0A4Y0BIB7	Uncharacterized protein. (658 aa)
	A0A4Y0BIF8	PH domain-containing protein. (1370 aa)
	A0A4Y0BIQ4	Uncharacterized protein. (380 aa)
	A0A4Y0BIU0	Uncharacterized protein. (1321 aa)
	A0A4Y0BIU1	Uncharacterized protein. (1010 aa)
	A0A4Y0BJL5	Uncharacterized protein. (2330 aa)
	A0A4Y0BJV6	Uncharacterized protein. (1892 aa)
	A0A4Y0BJX4	Uncharacterized protein. (1758 aa)
	A0A4Y0BJY5	Rap-GAP domain-containing protein. (941 aa)
	A0A4Y0BK94	Uncharacterized protein. (1446 aa)
	A0A4Y0BKJ0	Rap-GAP domain-containing protein. (1010 aa)
	A0A4Y0BL32	Uncharacterized protein. (1135 aa)
	A0A4Y0BLD6	Uncharacterized protein. (3379 aa)
	A0A4Y0BLI4	Uncharacterized protein. (211 aa)
	A0A4Y0BLJ0	Uncharacterized protein. (1978 aa)
	A0A4Y0BLS3	Uncharacterized protein. (192 aa)
	A0A4Y0BM25	WH1 domain-containing protein. (380 aa)
	A0A4Y0BM73	Uncharacterized protein. (911 aa)
	A0A4Y0BM81	Uncharacterized protein. (282 aa)
	A0A4Y0BN51	Uncharacterized protein. (412 aa)
	A0A4Y0BNG5	Uncharacterized protein. (2986 aa)
	A0A4Y0BNK3	Uncharacterized protein. (1545 aa)
	A0A4Y0BNP3	Uncharacterized protein. (257 aa)
	A0A4Y0BPE8	Uncharacterized protein. (673 aa)
	A0A4Y0BPF5	Uncharacterized protein. (201 aa)
	A0A4Y0BPH3	Uncharacterized protein. (2431 aa)
	A0A4Y0BPJ8	Uncharacterized protein. (1143 aa)
	A0A4Y0BPT0	Uncharacterized protein. (2153 aa)
	A0A4Y0BPV3	Uncharacterized protein. (469 aa)
	A0A4Y0BQE6	Rap-GAP domain-containing protein. (912 aa)
	A0A4Y0BQQ2	Uncharacterized protein. (1921 aa)
	A0A4Y0BQQ8	Uncharacterized protein. (1735 aa)
	A0A4Y0BRE5	Uncharacterized protein. (604 aa)
	A0A4Y0BRP3	GBD/FH3 domain-containing protein. (871 aa)
	A0A4Y0BRV6	Uncharacterized protein. (207 aa)
	A0A4Y0BTM6	Uncharacterized protein. (146 aa)
	A0A4Y0BWA1	GBD/FH3 domain-containing protein. (1046 aa)
	A0A4Y0BWC3	Uncharacterized protein. (215 aa)
	A0A4Y0BWL9	Uncharacterized protein. (1701 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R1H2	A0A182R1K6	Uncharacterized protein.	Uncharacterized protein.	0.566
A0A182R1H2	A0A182R4B1	Uncharacterized protein.	Rho-GAP domain-containing protein.	0.567
A0A182R1H2	A0A182R4B7	Uncharacterized protein.	Uncharacterized protein.	0.405
A0A182R1H2	A0A182R656	Uncharacterized protein.	Uncharacterized protein.	0.646
A0A182R1H2	A0A182R8V6	Uncharacterized protein.	Rho-GAP domain-containing protein.	0.601
A0A182R1H2	A0A182RAI9	Uncharacterized protein.	Uncharacterized protein.	0.803
A0A182R1H2	A0A182RB14	Uncharacterized protein.	Uncharacterized protein.	0.594
A0A182R1H2	A0A182RB32	Uncharacterized protein.	Uncharacterized protein.	0.505
A0A182R1H2	A0A182RBE8	Uncharacterized protein.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.844
A0A182R1H2	A0A182RC06	Uncharacterized protein.	Uncharacterized protein.	0.655
A0A182R1H2	A0A182REJ9	Uncharacterized protein.	Uncharacterized protein.	0.902
A0A182R1H2	A0A182REK6	Uncharacterized protein.	Uncharacterized protein.	0.611
A0A182R1H2	A0A182RGP4	Uncharacterized protein.	Uncharacterized protein.	0.642
A0A182R1H2	A0A182RH59	Uncharacterized protein.	Uncharacterized protein.	0.702
A0A182R1H2	A0A182RHF1	Uncharacterized protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.490
A0A182R1H2	A0A182RI03	Uncharacterized protein.	Rho-GAP domain-containing protein.	0.569
A0A182R1H2	A0A182RJF3	Uncharacterized protein.	Uncharacterized protein.	0.509
A0A182R1H2	A0A182RJG6	Uncharacterized protein.	Uncharacterized protein.	0.580
A0A182R1H2	A0A182RJK1	Uncharacterized protein.	Uncharacterized protein.	0.786
A0A182R1H2	A0A182RJW0	Uncharacterized protein.	Uncharacterized protein.	0.720