(7 nodes) Mixed, incl. Formin, FH3 domain, and Sequestering of actin monomers network (Anopheles funestus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182R1K6	Uncharacterized protein. (1823 aa)
	A0A182RHF1	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	A0A182S528	Uncharacterized protein. (376 aa)
	A0A4Y0B7J2	Uncharacterized protein. (1411 aa)
	A0A4Y0BM73	Uncharacterized protein. (911 aa)
	A0A4Y0BPJ8	Uncharacterized protein. (1143 aa)
	A0A4Y0BRP3	GBD/FH3 domain-containing protein. (871 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R1K6	A0A182RHF1	Uncharacterized protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.953
A0A182R1K6	A0A182S528	Uncharacterized protein.	Uncharacterized protein.	0.691
A0A182R1K6	A0A4Y0BM73	Uncharacterized protein.	Uncharacterized protein.	0.636
A0A182R1K6	A0A4Y0BPJ8	Uncharacterized protein.	Uncharacterized protein.	0.727
A0A182R1K6	A0A4Y0BRP3	Uncharacterized protein.	GBD/FH3 domain-containing protein.	0.616
A0A182RHF1	A0A182R1K6	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.953
A0A182RHF1	A0A182S528	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.855
A0A182RHF1	A0A4Y0B7J2	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.571
A0A182RHF1	A0A4Y0BM73	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.807
A0A182RHF1	A0A4Y0BPJ8	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.823
A0A182RHF1	A0A4Y0BRP3	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	GBD/FH3 domain-containing protein.	0.740
A0A182S528	A0A182R1K6	Uncharacterized protein.	Uncharacterized protein.	0.691
A0A182S528	A0A182RHF1	Uncharacterized protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.855
A0A182S528	A0A4Y0B7J2	Uncharacterized protein.	Uncharacterized protein.	0.648
A0A182S528	A0A4Y0BM73	Uncharacterized protein.	Uncharacterized protein.	0.436
A0A182S528	A0A4Y0BPJ8	Uncharacterized protein.	Uncharacterized protein.	0.680
A0A182S528	A0A4Y0BRP3	Uncharacterized protein.	GBD/FH3 domain-containing protein.	0.599
A0A4Y0B7J2	A0A182RHF1	Uncharacterized protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.571
A0A4Y0B7J2	A0A182S528	Uncharacterized protein.	Uncharacterized protein.	0.648
A0A4Y0B7J2	A0A4Y0BM73	Uncharacterized protein.	Uncharacterized protein.	0.593