(52 nodes) Mixed, incl. SH2 domain superfamily, and IRS-mediated signalling network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182R219	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1171 aa)
	A0A182R222	Tyrosine-protein kinase receptor. (2512 aa)
	A0A182R2L5	Uncharacterized protein. (678 aa)
	A0A182R465	Uncharacterized protein. (1015 aa)
	A0A182R4M8	Uncharacterized protein. (201 aa)
	A0A182R5P1	Uncharacterized protein; Belongs to the DOCK family. (1087 aa)
	A0A182R6I6	Uncharacterized protein. (1862 aa)
	A0A182R6Y5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (716 aa)
	A0A182R7N8	Uncharacterized protein. (403 aa)
	A0A182R9Y3	Uncharacterized protein. (191 aa)
	A0A182RAR1	Protein kinase domain-containing protein. (1623 aa)
	A0A182RB29	Uncharacterized protein. (1374 aa)
	A0A182RD46	Uncharacterized protein. (1419 aa)
	A0A182RD62	Uncharacterized protein. (193 aa)
	A0A182RFH5	PH domain-containing protein. (912 aa)
	A0A182RG46	ELMO domain-containing protein. (722 aa)
	A0A182RGE0	Uncharacterized protein. (272 aa)
	A0A182RH15	Uncharacterized protein. (190 aa)
	A0A182RIP6	Uncharacterized protein. (1033 aa)
	A0A182RMT5	Uncharacterized protein. (562 aa)
	A0A182RPG5	Uncharacterized protein. (178 aa)
	A0A182RR66	Tyrosine-protein kinase. (537 aa)
	A0A182RRA6	IRS-type PTB domain-containing protein. (746 aa)
	A0A182RTI1	Uncharacterized protein. (1154 aa)
	A0A182RVX9	Uncharacterized protein. (1558 aa)
	A0A182RXB6	Uncharacterized protein. (196 aa)
	A0A182S133	SH2 domain-containing protein. (199 aa)
	A0A1Y9HF07	Tyrosine-protein kinase. (1272 aa)
	A0A4Y0ALV6	Uncharacterized protein. (1238 aa)
	A0A4Y0AN43	Uncharacterized protein. (695 aa)
	A0A4Y0B206	Receptor protein-tyrosine kinase. (1488 aa)
	A0A4Y0BDI4	Tyrosine-protein kinase. (726 aa)
	A0A4Y0BFZ0	Uncharacterized protein. (1082 aa)
	A0A4Y0BGP8	Uncharacterized protein. (548 aa)
	A0A4Y0BGX9	Uncharacterized protein; Belongs to the DOCK family. (2096 aa)
	A0A4Y0BH85	Uncharacterized protein. (1552 aa)
	A0A4Y0BHE1	Uncharacterized protein. (1511 aa)
	A0A4Y0BID7	Uncharacterized protein. (769 aa)
	A0A4Y0BIF9	Uncharacterized protein. (620 aa)
	A0A4Y0BJ12	Tyrosine-protein kinase. (508 aa)
	A0A4Y0BJ45	Uncharacterized protein. (711 aa)
	A0A4Y0BJT5	Uncharacterized protein. (469 aa)
	A0A4Y0BKH0	Uncharacterized protein. (779 aa)
	A0A4Y0BL46	Uncharacterized protein. (644 aa)
	A0A4Y0BLJ8	Uncharacterized protein. (2200 aa)
	A0A4Y0BM24	Uncharacterized protein. (2577 aa)
	A0A4Y0BM97	Uncharacterized protein. (933 aa)
	A0A4Y0BMV7	Uncharacterized protein. (356 aa)
	A0A4Y0BN26	Uncharacterized protein. (211 aa)
	A0A4Y0BP24	Tyrosine-protein kinase. (808 aa)
	A0A4Y0BQ21	Uncharacterized protein. (675 aa)
	A0A4Y0BTF1	Uncharacterized protein. (420 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R219	A0A182R222	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Tyrosine-protein kinase receptor.	0.841
A0A182R219	A0A182R2L5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.676
A0A182R219	A0A182R465	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.623
A0A182R219	A0A182R4M8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.864
A0A182R219	A0A182R6I6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.879
A0A182R219	A0A182R6Y5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.737
A0A182R219	A0A182R9Y3	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.771
A0A182R219	A0A182RAR1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.856
A0A182R219	A0A182RB29	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.509
A0A182R219	A0A182RD62	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.771
A0A182R219	A0A182RFH5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	PH domain-containing protein.	0.799
A0A182R219	A0A182RGE0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.830
A0A182R219	A0A182RH15	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.984
A0A182R219	A0A182RIP6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.817
A0A182R219	A0A182RMT5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.581
A0A182R219	A0A182RR66	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Tyrosine-protein kinase.	0.711
A0A182R219	A0A182RRA6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	IRS-type PTB domain-containing protein.	0.671
A0A182R219	A0A182RTI1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.633
A0A182R219	A0A182RVX9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.673
A0A182R219	A0A182RXB6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.771