(71 nodes) Mixed, incl. Apoptosis - multiple species, and Regulation of I-kappaB kinase/NF-kappaB signaling network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182R1G8	Protein kinase domain-containing protein. (1128 aa)
	A0A182R2D2	PPM-type phosphatase domain-containing protein. (431 aa)
	A0A182R4I4	Uncharacterized protein. (206 aa)
	A0A182R5L7	PPM-type phosphatase domain-containing protein. (1045 aa)
	A0A182R628	Uncharacterized protein. (582 aa)
	A0A182R670	Uncharacterized protein. (686 aa)
	A0A182R6J6	Protein kinase domain-containing protein. (804 aa)
	A0A182R7U5	Thioredoxin-like_fold domain-containing protein. (751 aa)
	A0A182R916	Uncharacterized protein. (409 aa)
	A0A182R920	Uncharacterized protein. (1166 aa)
	A0A182R9C7	Protein kinase domain-containing protein. (754 aa)
	A0A182R9F3	Uncharacterized protein. (1141 aa)
	A0A182RBJ1	Uncharacterized protein; Belongs to the peptidase C14A family. (290 aa)
	A0A182RCL6	Death domain-containing protein. (249 aa)
	A0A182RE56	Death domain-containing protein. (272 aa)
	A0A182RG40	Uncharacterized protein. (1284 aa)
	A0A182RG44	Uncharacterized protein. (2051 aa)
	A0A182RGB3	Mitogen-activated protein kinase. (387 aa)
	A0A182RHM2	TRAF-type domain-containing protein. (383 aa)
	A0A182RHT3	Protein kinase domain-containing protein. (607 aa)
	A0A182RII9	Uncharacterized protein. (460 aa)
	A0A182RJS9	DH domain-containing protein. (1554 aa)
	A0A182RL27	Uncharacterized protein. (1411 aa)
	A0A182RLG1	Uncharacterized protein; Belongs to the peptidase C14A family. (293 aa)
	A0A182RLG2	Uncharacterized protein; Belongs to the peptidase C14A family. (309 aa)
	A0A182RLK0	RING-type domain-containing protein. (212 aa)
	A0A182RM62	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (380 aa)
	A0A182RMT7	Uncharacterized protein; Belongs to the peptidase C14A family. (313 aa)
	A0A182RNB0	TOLL pathway signalling Ser/Thr kinase. (506 aa)
	A0A182RNC9	Uncharacterized protein. (248 aa)
	A0A182RNS2	Uncharacterized protein. (381 aa)
	A0A182RTZ1	RING-type domain-containing protein. (528 aa)
	A0A182RUG1	Uncharacterized protein. (217 aa)
	A0A182RVG4	Uncharacterized protein. (1208 aa)
	A0A182RVY5	Uncharacterized protein. (639 aa)
	A0A182RWD2	PPM-type phosphatase domain-containing protein. (530 aa)
	A0A182RWK9	Uncharacterized protein; Belongs to the peptidase C14A family. (352 aa)
	A0A182RWN5	Uncharacterized protein. (483 aa)
	A0A182RXU4	Uncharacterized protein; Belongs to the peptidase C14A family. (311 aa)
	A0A182RXU5	Uncharacterized protein; Belongs to the peptidase C14A family. (240 aa)
	A0A182RXV6	Uncharacterized protein; Belongs to the intermediate filament family. (567 aa)
	A0A182RXZ9	Protein kinase domain-containing protein. (690 aa)
	A0A182RZR2	CCHC NOA-type domain-containing protein. (546 aa)
	A0A1I8JUX2	Short caspase; Belongs to the peptidase C14A family. (309 aa)
	A0A1Y9HET6	Mitogen-activated protein kinase kinase kinase 7-interacting protein. (456 aa)
	A0A3F2YXN7	DUF4203 domain-containing protein. (366 aa)
	A0A3F2YXQ1	Uncharacterized protein; Belongs to the peptidase C14A family. (496 aa)
	A0A4Y0AZK8	DH domain-containing protein. (1443 aa)
	A0A4Y0B0X2	Protein kinase domain-containing protein. (597 aa)
	A0A4Y0B8N3	Uncharacterized protein. (1234 aa)
	A0A4Y0B9Y4	Uncharacterized protein. (446 aa)
	A0A4Y0BCM9	Uncharacterized protein. (544 aa)
	A0A4Y0BDY1	RING-type domain-containing protein. (329 aa)
	A0A4Y0BEZ6	CCHC NOA-type domain-containing protein. (546 aa)
	A0A4Y0BFK8	DH domain-containing protein. (929 aa)
	A0A4Y0BFL2	Microtubule-associated protein. (304 aa)
	A0A4Y0BFM2	RanBP2-type domain-containing protein. (1458 aa)
	A0A4Y0BFS3	Thioredoxin-like_fold domain-containing protein. (751 aa)
	A0A4Y0BI09	Uncharacterized protein. (7433 aa)
	A0A4Y0BI11	Microtubule-associated protein. (340 aa)
	A0A4Y0BIF2	Mitogen-activated protein kinase. (358 aa)
	A0A4Y0BJJ5	Tyrosine-protein kinase. (641 aa)
	A0A4Y0BJJ7	Protein kinase domain-containing protein. (1545 aa)
	A0A4Y0BK79	Tyrosine-protein kinase. (676 aa)
	A0A4Y0BLS2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (392 aa)
	A0A4Y0BM66	RING-type domain-containing protein. (328 aa)
	A0A4Y0BQD2	Uncharacterized protein; Belongs to the peptidase C14A family. (430 aa)
	A0A4Y0BQZ2	Aa_trans domain-containing protein. (517 aa)
	A0A4Y0BR70	RanBP2-type domain-containing protein. (1272 aa)
	A0A4Y0BSE8	PDZ domain-containing protein. (428 aa)
	A0A4Y0BWL2	RING-type domain-containing protein. (2271 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R1G8	A0A182R2D2	Protein kinase domain-containing protein.	PPM-type phosphatase domain-containing protein.	0.597
A0A182R1G8	A0A182R5L7	Protein kinase domain-containing protein.	PPM-type phosphatase domain-containing protein.	0.597
A0A182R1G8	A0A182R670	Protein kinase domain-containing protein.	Uncharacterized protein.	0.597
A0A182R1G8	A0A182R6J6	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.571
A0A182R1G8	A0A182R7U5	Protein kinase domain-containing protein.	Thioredoxin-like_fold domain-containing protein.	0.655
A0A182R1G8	A0A182R916	Protein kinase domain-containing protein.	Uncharacterized protein.	0.611
A0A182R1G8	A0A182R9C7	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.516
A0A182R1G8	A0A182RGB3	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.991
A0A182R1G8	A0A182RHM2	Protein kinase domain-containing protein.	TRAF-type domain-containing protein.	0.797
A0A182R1G8	A0A182RHT3	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.807
A0A182R1G8	A0A182RNB0	Protein kinase domain-containing protein.	TOLL pathway signalling Ser/Thr kinase.	0.684
A0A182R1G8	A0A182RNC9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.972
A0A182R1G8	A0A182RNS2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.664
A0A182R1G8	A0A182RWD2	Protein kinase domain-containing protein.	PPM-type phosphatase domain-containing protein.	0.597
A0A182R1G8	A0A182RWN5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.672
A0A182R1G8	A0A182RXZ9	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.623
A0A182R1G8	A0A182RZR2	Protein kinase domain-containing protein.	CCHC NOA-type domain-containing protein.	0.533
A0A182R1G8	A0A1Y9HET6	Protein kinase domain-containing protein.	Mitogen-activated protein kinase kinase kinase 7-interacting protein.	0.807
A0A182R1G8	A0A4Y0B0X2	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.980
A0A182R1G8	A0A4Y0B8N3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.879