(37 nodes) Spliceosomal snRNP complex network (Anopheles funestus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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Your Input:
	A0A182R3H7	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (126 aa)
	A0A182R4W5	Uncharacterized protein. (413 aa)
	A0A182R650	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family. (152 aa)
	A0A182R705	Tr-type G domain-containing protein. (974 aa)
	A0A182R7C7	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (184 aa)
	A0A182R8Q5	Uncharacterized protein. (775 aa)
	A0A182R8S1	PSP domain-containing protein. (924 aa)
	A0A182RB48	Uncharacterized protein. (247 aa)
	A0A182RF90	Uncharacterized protein. (931 aa)
	A0A182RFF6	Small nuclear ribonucleoprotein Sm D3. (143 aa)
	A0A182RGE5	WD_REPEATS_REGION domain-containing protein. (350 aa)
	A0A182RJ86	Uncharacterized protein. (691 aa)
	A0A182RJF1	MPN domain-containing protein. (2389 aa)
	A0A182RLW9	Uncharacterized protein. (1077 aa)
	A0A182RMD6	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
	A0A182RMG1	CPSF_A domain-containing protein. (1216 aa)
	A0A182RN81	WD_REPEATS_REGION domain-containing protein. (505 aa)
	A0A182RPE6	RRM domain-containing protein. (126 aa)
	A0A182RQL1	Sm domain-containing protein; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (88 aa)
	A0A182RQN4	U1 small nuclear ribonucleoprotein A. (216 aa)
	A0A182RTI7	Small nuclear ribonucleoprotein G. (60 aa)
	A0A182RVI7	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (85 aa)
	A0A182RVL3	Uncharacterized protein. (817 aa)
	A0A182RWC3	Uncharacterized protein. (1001 aa)
	A0A1D6TCB7	Small nuclear ribonucleoprotein G. (76 aa)
	A0A4Y0BDJ6	Nop domain-containing protein. (512 aa)
	A0A4Y0BF61	PSP domain-containing protein. (924 aa)
	A0A4Y0BFI8	TOG domain-containing protein. (1320 aa)
	A0A4Y0BGB8	PID domain-containing protein. (861 aa)
	A0A4Y0BIG0	TOG domain-containing protein. (1320 aa)
	A0A4Y0BM85	Uncharacterized protein. (823 aa)
	A0A4Y0BNK7	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (90 aa)
	A0A4Y0BNM4	Small nuclear ribonucleoprotein Sm D2. (119 aa)
	A0A4Y0BNW5	Uncharacterized protein. (2173 aa)
	A0A4Y0BPS4	Small nuclear ribonucleoprotein-associated protein. (202 aa)
	A0A4Y0BPU9	Sm domain-containing protein. (131 aa)
	A0A4Y0BR79	Uncharacterized protein. (109 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R3H7	A0A182R4W5	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Uncharacterized protein.	0.981
A0A182R3H7	A0A182R650	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.	0.996
A0A182R3H7	A0A182R705	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Tr-type G domain-containing protein.	0.998
A0A182R3H7	A0A182R7C7	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.966
A0A182R3H7	A0A182R8Q5	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Uncharacterized protein.	0.952
A0A182R3H7	A0A182R8S1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	PSP domain-containing protein.	0.968
A0A182R3H7	A0A182RB48	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Uncharacterized protein.	0.998
A0A182R3H7	A0A182RF90	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Uncharacterized protein.	0.997
A0A182R3H7	A0A182RFF6	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Small nuclear ribonucleoprotein Sm D3.	0.999
A0A182R3H7	A0A182RGE5	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	WD_REPEATS_REGION domain-containing protein.	0.988
A0A182R3H7	A0A182RJ86	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Uncharacterized protein.	0.986
A0A182R3H7	A0A182RJF1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	MPN domain-containing protein.	0.997
A0A182R3H7	A0A182RLW9	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Uncharacterized protein.	0.996
A0A182R3H7	A0A182RMD6	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.	0.979
A0A182R3H7	A0A182RMG1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	CPSF_A domain-containing protein.	0.989
A0A182R3H7	A0A182RN81	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	WD_REPEATS_REGION domain-containing protein.	0.971
A0A182R3H7	A0A182RPE6	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	RRM domain-containing protein.	0.976
A0A182R3H7	A0A182RQL1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Sm domain-containing protein; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.999
A0A182R3H7	A0A182RQN4	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	U1 small nuclear ribonucleoprotein A.	0.998
A0A182R3H7	A0A182RTI7	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Small nuclear ribonucleoprotein G.	0.998