29 items (Anopheles funestus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182RCN4	Uncharacterized protein. (929 aa)
	A0A182RAG7	NFRKB_winged domain-containing protein. (2116 aa)
	A0A182R915	Lactamase_B domain-containing protein. (788 aa)
	A0A182R8X4	Uncharacterized protein. (1992 aa)
	A0A182R8E4	RECA_2 domain-containing protein. (262 aa)
	A0A182R6N9	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (649 aa)
	A0A4Y0BUJ9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2289 aa)
	A0A4Y0BQ50	Ku domain-containing protein. (728 aa)
	A0A4Y0BNX5	Peptidase C50 domain-containing protein. (531 aa)
	A0A4Y0BJZ8	FAT domain-containing protein. (530 aa)
	A0A4Y0BH26	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3253 aa)
	A0A4Y0BGS0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (428 aa)
	A0A4Y0BG00	Uncharacterized protein. (206 aa)
	A0A4Y0BEH6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1674 aa)
	A0A4Y0BDQ7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2661 aa)
	A0A4Y0B5Z4	Uncharacterized protein. (116 aa)
	A0A182RZ53	DRMBL domain-containing protein. (403 aa)
	A0A182RWW4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (4170 aa)
	A0A182RVF7	Checkpoint protein; Belongs to the HUS1 family. (293 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (672 aa)
	A0A182RTH7	Ku domain-containing protein. (622 aa)
	A0A182RSA0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2649 aa)
	A0A182RRS7	Zinc-hook domain-containing protein. (1308 aa)
	A0A182RRB4	Uncharacterized protein. (141 aa)
	A0A182RPL3	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
	A0A182RMV3	Regulator of telomere elongation helicase 1 homolog; ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. (977 aa)
	A0A182RIW4	FHA domain-containing protein. (772 aa)
	A0A182RHU9	Uncharacterized protein; Belongs to the ATP-dependent DNA ligase family. (921 aa)
	A0A182RDL1	RECA_2 domain-containing protein. (329 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A182R6N9	A0A182R8E4	A0A182R6N9	A0A182R8E4	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	RECA_2 domain-containing protein.	0.920
A0A182R6N9	A0A182R8X4	A0A182R6N9	A0A182R8X4	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.588
A0A182R6N9	A0A182R915	A0A182R6N9	A0A182R915	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Lactamase_B domain-containing protein.	0.831
A0A182R6N9	A0A182RDL1	A0A182R6N9	A0A182RDL1	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	RECA_2 domain-containing protein.	0.938
A0A182R6N9	A0A182RHU9	A0A182R6N9	A0A182RHU9	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein; Belongs to the ATP-dependent DNA ligase family.	0.836
A0A182R6N9	A0A182RIW4	A0A182R6N9	A0A182RIW4	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	FHA domain-containing protein.	0.999
A0A182R6N9	A0A182RMV3	A0A182R6N9	A0A182RMV3	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Regulator of telomere elongation helicase 1 homolog; ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates.	0.974
A0A182R6N9	A0A182RPL3	A0A182R6N9	A0A182RPL3	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.974
A0A182R6N9	A0A182RRB4	A0A182R6N9	A0A182RRB4	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.947
A0A182R6N9	A0A182RRS7	A0A182R6N9	A0A182RRS7	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Zinc-hook domain-containing protein.	0.999
A0A182R6N9	A0A182RSA0	A0A182R6N9	A0A182RSA0	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.957
A0A182R6N9	A0A182RTH7	A0A182R6N9	A0A182RTH7	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Ku domain-containing protein.	0.988
A0A182R6N9	A0A182RVF7	A0A182R6N9	A0A182RVF7	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Checkpoint protein; Belongs to the HUS1 family.	0.846
A0A182R6N9	A0A182RWW4	A0A182R6N9	A0A182RWW4	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.832
A0A182R6N9	A0A182RZ53	A0A182R6N9	A0A182RZ53	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	DRMBL domain-containing protein.	0.835
A0A182R6N9	A0A4Y0B5Z4	A0A182R6N9	A0A4Y0B5Z4	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.947
A0A182R6N9	A0A4Y0BDQ7	A0A182R6N9	A0A4Y0BDQ7	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.957
A0A182R6N9	A0A4Y0BGS0	A0A182R6N9	A0A4Y0BGS0	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.960
A0A182R6N9	A0A4Y0BH26	A0A182R6N9	A0A4Y0BH26	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.677
A0A182R6N9	A0A4Y0BJZ8	A0A182R6N9	A0A4Y0BJZ8	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	FAT domain-containing protein.	0.960