STRINGSTRING
A0A182R1J3 A0A182R1J3 MCM7 MCM7 A0A182R422 A0A182R422 A0A182R423 A0A182R423 A0A182R433 A0A182R433 A0A182R4B0 A0A182R4B0 A0A182R4N6 A0A182R4N6 A0A182R534 A0A182R534 A0A182R5W4 A0A182R5W4 A0A182R6N9 A0A182R6N9 A0A182R6W1 A0A182R6W1 A0A182R700 A0A182R700 A0A182R703 A0A182R703 A0A182R723 A0A182R723 A0A182R7K0 A0A182R7K0 A0A182R7S6 A0A182R7S6 A0A182R8E4 A0A182R8E4 A0A182R8V4 A0A182R8V4 A0A182RA52 A0A182RA52 A0A182RCK2 A0A182RCK2 A0A182RDL1 A0A182RDL1 A0A182RE53 A0A182RE53 A0A182REC8 A0A182REC8 A0A182RF05 A0A182RF05 A0A182RF93 A0A182RF93 A0A182RG11 A0A182RG11 A0A182RG25 A0A182RG25 A0A182RH57 A0A182RH57 A0A182RHR0 A0A182RHR0 A0A182RI25 A0A182RI25 A0A182RIW4 A0A182RIW4 A0A182RJL5 A0A182RJL5 A0A182RNA9 A0A182RNA9 A0A182RND2 A0A182RND2 A0A182RPL3 A0A182RPL3 A0A182RQ96 A0A182RQ96 A0A182RQD1 A0A182RQD1 A0A182RR05 A0A182RR05 A0A182RS85 A0A182RS85 A0A182RSA0 A0A182RSA0 A0A182RT78 A0A182RT78 A0A182RU09 A0A182RU09 PIF1 PIF1 A0A182RUV4 A0A182RUV4 A0A182RVF7 A0A182RVF7 A0A182RVP3 A0A182RVP3 A0A182RVY7 A0A182RVY7 A0A182RW23 A0A182RW23 A0A182RWN4 A0A182RWN4 A0A182RX78 A0A182RX78 A0A182RXT7 A0A182RXT7 A0A182RZQ7 A0A182RZQ7 A0A182S019 A0A182S019 A0A3F2YXQ5 A0A3F2YXQ5 A0A4Y0ARG3 A0A4Y0ARG3 A0A4Y0B535 A0A4Y0B535 A0A4Y0BDQ7 A0A4Y0BDQ7 A0A4Y0BEI8 A0A4Y0BEI8 A0A4Y0BFV6 A0A4Y0BFV6 A0A4Y0BGM0 A0A4Y0BGM0 A0A4Y0BKG0 A0A4Y0BKG0 A0A4Y0BN17 A0A4Y0BN17 A0A4Y0BNH7 A0A4Y0BNH7 A0A4Y0BNI3 A0A4Y0BNI3 A0A4Y0BNT1 A0A4Y0BNT1 A0A4Y0BPI2 A0A4Y0BPI2 A0A4Y0BQ78 A0A4Y0BQ78 A0A4Y0BTX5 A0A4Y0BTX5 A0A4Y0BU86 A0A4Y0BU86
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
A0A182R1J3MCM domain-containing protein; Belongs to the MCM family. (1095 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (717 aa)
A0A182R422Uncharacterized protein. (825 aa)
A0A182R423SUN domain-containing protein. (265 aa)
A0A182R433Uncharacterized protein. (785 aa)
A0A182R4B0ERCC4 domain-containing protein. (480 aa)
A0A182R4N6ERCC4 domain-containing protein. (1041 aa)
A0A182R534Uncharacterized protein. (1034 aa)
A0A182R5W4RECA_2 domain-containing protein. (140 aa)
A0A182R6N9Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (649 aa)
A0A182R6W1DNA helicase; Belongs to the MCM family. (812 aa)
A0A182R700ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (660 aa)
A0A182R703DUF1767 domain-containing protein. (642 aa)
A0A182R723ANK_REP_REGION domain-containing protein. (1529 aa)
A0A182R7K0Uncharacterized protein. (1384 aa)
A0A182R7S6Uncharacterized protein. (120 aa)
A0A182R8E4RECA_2 domain-containing protein. (262 aa)
A0A182R8V4Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (872 aa)
A0A182RA52ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (819 aa)
A0A182RCK2Uncharacterized protein. (2053 aa)
A0A182RDL1RECA_2 domain-containing protein. (329 aa)
A0A182RE53DNA helicase; Belongs to the MCM family. (876 aa)
A0A182REC8ANK_REP_REGION domain-containing protein. (654 aa)
A0A182RF05Uncharacterized protein. (1628 aa)
A0A182RF93RING-type domain-containing protein. (735 aa)
A0A182RG11DNA helicase; Belongs to the MCM family. (822 aa)
A0A182RG25Uncharacterized protein; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (720 aa)
A0A182RH57Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (356 aa)
A0A182RHR0AAA_23 domain-containing protein. (1038 aa)
A0A182RI25DNA helicase; Belongs to the MCM family. (733 aa)
A0A182RIW4FHA domain-containing protein. (772 aa)
A0A182RJL5Uncharacterized protein. (881 aa)
A0A182RNA9Uncharacterized protein. (1459 aa)
A0A182RND2DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (339 aa)
A0A182RPL3Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
A0A182RQ96Uncharacterized protein. (235 aa)
A0A182RQD1FYVE-type domain-containing protein. (1799 aa)
A0A182RR05WD_REPEATS_REGION domain-containing protein. (710 aa)
A0A182RS85Uncharacterized protein. (1351 aa)
A0A182RSA0Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2649 aa)
A0A182RT78Protein kinase domain-containing protein. (569 aa)
A0A182RU09Uncharacterized protein. (552 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (672 aa)
A0A182RUV4Uncharacterized protein. (668 aa)
A0A182RVF7Checkpoint protein; Belongs to the HUS1 family. (293 aa)
A0A182RVP3Uncharacterized protein. (1075 aa)
A0A182RVY7Uncharacterized protein. (69 aa)
A0A182RW23TP6A_N domain-containing protein. (286 aa)
A0A182RWN4DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (205 aa)
A0A182RX78DNA helicase; Belongs to the MCM family. (899 aa)
A0A182RXT7Uncharacterized protein. (569 aa)
A0A182RZQ7DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1178 aa)
A0A182S019Rad51 domain-containing protein. (310 aa)
A0A3F2YXQ5Uncharacterized protein. (236 aa)
A0A4Y0ARG3Uncharacterized protein. (1513 aa)
A0A4Y0B535SUN domain-containing protein. (1141 aa)
A0A4Y0BDQ7Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2661 aa)
A0A4Y0BEI8DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (680 aa)
A0A4Y0BFV6GIY-YIG domain-containing protein. (184 aa)
A0A4Y0BGM0Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (872 aa)
A0A4Y0BKG0Uncharacterized protein. (2242 aa)
A0A4Y0BN17SP-RING-type domain-containing protein. (201 aa)
A0A4Y0BNH7Nipped-B protein. (2194 aa)
A0A4Y0BNI3DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1001 aa)
A0A4Y0BNT1Uncharacterized protein. (726 aa)
A0A4Y0BPI2SMC_N domain-containing protein. (1088 aa)
A0A4Y0BQ78DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (237 aa)
A0A4Y0BTX5MCM domain-containing protein; Belongs to the MCM family. (832 aa)
A0A4Y0BU86Uncharacterized protein. (804 aa)
Your Current Organism:
Anopheles funestus
NCBI taxonomy Id: 62324
Other names: A. funestus
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