28 items (Anopheles funestus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	A0A4Y0BLV8	Uncharacterized protein. (376 aa)
	A0A182R3A9	Endonuclease. (318 aa)
	A0A182R3W6	CIDE-N domain-containing protein. (421 aa)
	A0A182R4B0	ERCC4 domain-containing protein. (480 aa)
	A0A182R4C6	Uncharacterized protein. (386 aa)
	A0A182R4N6	ERCC4 domain-containing protein. (1041 aa)
	A0A182R5E4	Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1683 aa)
	A0A182R6N9	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (649 aa)
	A0A182RAL5	Endonuclease_NS domain-containing protein. (397 aa)
	A0A182RE24	Uncharacterized protein. (410 aa)
	A0A182REC8	ANK_REP_REGION domain-containing protein. (654 aa)
	Fen1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (383 aa)
	A0A182RKD7	Endonuclease_NS domain-containing protein. (430 aa)
	A0A182RM05	Uncharacterized protein. (1384 aa)
	A0A182RPL1	Uncharacterized protein. (2315 aa)
	A0A182RQM2	Uncharacterized protein. (735 aa)
	A0A182RS86	Uncharacterized protein. (1151 aa)
	A0A182RUK6	Uncharacterized protein. (424 aa)
	A0A182RZI1	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (315 aa)
	A0A182RZK4	Uncharacterized protein. (855 aa)
	A0A1I8JUQ3	Uncharacterized protein. (1124 aa)
	A0A4Y0BW18	Endonuclease_NS domain-containing protein. (452 aa)
	A0A4Y0BQK8	Endonuclease_NS domain-containing protein. (397 aa)
	A0A4Y0BDX3	Uncharacterized protein. (421 aa)
	A0A4Y0BFV6	GIY-YIG domain-containing protein. (184 aa)
	A0A4Y0BI95	Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (974 aa)
	A0A4Y0BPR9	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (646 aa)
	A0A182RH57	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (356 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A182R3A9	A0A182RM05	A0A182R3A9	A0A182RM05	Endonuclease.	Uncharacterized protein.	0.538
A0A182R3A9	A0A182RQM2	A0A182R3A9	A0A182RQM2	Endonuclease.	Uncharacterized protein.	0.659
A0A182R3A9	A0A182RS86	A0A182R3A9	A0A182RS86	Endonuclease.	Uncharacterized protein.	0.418
A0A182R3A9	A0A182RZK4	A0A182R3A9	A0A182RZK4	Endonuclease.	Uncharacterized protein.	0.538
A0A182R3A9	A0A4Y0BLV8	A0A182R3A9	A0A4Y0BLV8	Endonuclease.	Uncharacterized protein.	0.400
A0A182R3A9	Fen1	A0A182R3A9	A0A182RFB4	Endonuclease.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.741
A0A182R4B0	A0A182R4N6	A0A182R4B0	A0A182R4N6	ERCC4 domain-containing protein.	ERCC4 domain-containing protein.	0.967
A0A182R4B0	A0A182R6N9	A0A182R4B0	A0A182R6N9	ERCC4 domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.853
A0A182R4B0	A0A182REC8	A0A182R4B0	A0A182REC8	ERCC4 domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.488
A0A182R4B0	A0A182RH57	A0A182R4B0	A0A182RH57	ERCC4 domain-containing protein.	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	0.857
A0A182R4B0	A0A182RM05	A0A182R4B0	A0A182RM05	ERCC4 domain-containing protein.	Uncharacterized protein.	0.969
A0A182R4B0	A0A182RQM2	A0A182R4B0	A0A182RQM2	ERCC4 domain-containing protein.	Uncharacterized protein.	0.910
A0A182R4B0	A0A182RS86	A0A182R4B0	A0A182RS86	ERCC4 domain-containing protein.	Uncharacterized protein.	0.880
A0A182R4B0	A0A182RZK4	A0A182R4B0	A0A182RZK4	ERCC4 domain-containing protein.	Uncharacterized protein.	0.943
A0A182R4B0	A0A4Y0BFV6	A0A182R4B0	A0A4Y0BFV6	ERCC4 domain-containing protein.	GIY-YIG domain-containing protein.	0.857
A0A182R4B0	A0A4Y0BPR9	A0A182R4B0	A0A4Y0BPR9	ERCC4 domain-containing protein.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.852
A0A182R4B0	Fen1	A0A182R4B0	A0A182RFB4	ERCC4 domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.928
A0A182R4C6	A0A182RZI1	A0A182R4C6	A0A182RZI1	Uncharacterized protein.	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.	0.621
A0A182R4N6	A0A182R4B0	A0A182R4N6	A0A182R4B0	ERCC4 domain-containing protein.	ERCC4 domain-containing protein.	0.967
A0A182R4N6	A0A182R6N9	A0A182R4N6	A0A182R6N9	ERCC4 domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.850