(102 nodes) Positive regulation of cell death network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4Y0BMS8	Uncharacterized protein. (603 aa)
	A0A3F2YXP8	Uncharacterized protein. (2757 aa)
	A0A4Y0AXE2	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (745 aa)
	A0A4Y0B8G1	Uncharacterized protein. (757 aa)
	A0A4Y0B9Y4	Uncharacterized protein. (446 aa)
	A0A4Y0BDI4	Tyrosine-protein kinase. (726 aa)
	A0A4Y0BFZ0	Uncharacterized protein. (1082 aa)
	A0A4Y0BG01	Homeobox domain-containing protein. (467 aa)
	A0A4Y0BG09	Protein kinase domain-containing protein. (842 aa)
	A0A4Y0BG95	USP domain-containing protein. (2259 aa)
	A0A4Y0BH18	Non-specific serine/threonine protein kinase. (686 aa)
	A0A4Y0BHL3	Uncharacterized protein. (1048 aa)
	A0A4Y0BHV3	USP domain-containing protein. (2240 aa)
	A0A4Y0BI50	Uncharacterized protein. (1285 aa)
	A0A4Y0BI87	Uncharacterized protein. (129 aa)
	A0A4Y0BIP3	USP domain-containing protein. (2145 aa)
	A0A4Y0BIX6	C2 NT-type domain-containing protein. (479 aa)
	A0A4Y0BJ92	Fork-head domain-containing protein. (472 aa)
	A0A4Y0BJU2	Uncharacterized protein. (202 aa)
	A0A4Y0BKM9	Homeobox domain-containing protein. (559 aa)
	A0A4Y0BL73	Uncharacterized protein. (375 aa)
	A0A4Y0BLG8	C2 NT-type domain-containing protein. (957 aa)
	A0A4Y0BLL2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (428 aa)
	A0A4Y0BLR0	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (506 aa)
	A0A4Y0BLS2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (392 aa)
	A0A4Y0BLU7	Uncharacterized protein. (1279 aa)
	A0A4Y0BME7	C2 NT-type domain-containing protein. (534 aa)
	A0A4Y0BMP5	Uncharacterized protein. (531 aa)
	A0A2Y9D1V1	Mediator of RNA polymerase II transcription subunit 12. (2788 aa)
	A0A4Y0BN13	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (254 aa)
	A0A4Y0BNB9	Uncharacterized protein. (187 aa)
	A0A4Y0BNL8	Uncharacterized protein. (271 aa)
	A0A4Y0BQD2	Uncharacterized protein; Belongs to the peptidase C14A family. (430 aa)
	A0A4Y0BQJ9	Uncharacterized protein. (341 aa)
	A0A4Y0BRL6	Uncharacterized protein. (5184 aa)
	A0A4Y0BRT9	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (406 aa)
	A0A4Y0BRZ0	Uncharacterized protein. (598 aa)
	A0A4Y0BSE8	PDZ domain-containing protein. (428 aa)
	A0A4Y0BT82	Uncharacterized protein. (663 aa)
	A0A182R1G8	Protein kinase domain-containing protein. (1128 aa)
	A0A182R1J4	GTP-binding protein Rheb. (182 aa)
	A0A182R1K0	40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (244 aa)
	A0A182R2M7	PWI domain-containing protein. (1361 aa)
	A0A182R5H7	Uncharacterized protein. (251 aa)
	A0A182R5P0	P53 domain-containing protein. (399 aa)
	A0A182R6A7	Uncharacterized protein. (2460 aa)
	A0A182R6I3	Plug_translocon domain-containing protein. (476 aa)
	A0A182R842	ARL2_Bind_BART domain-containing protein. (146 aa)
	A0A182R888	Uncharacterized protein. (855 aa)
	A0A182R919	Merlin (moesin-ezrin-radixin-like protein). (592 aa)
	A0A182R961	RING-type domain-containing protein. (446 aa)
	A0A182R9A7	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (515 aa)
	A0A182R9L8	FERM domain-containing protein. (1583 aa)
	A0A182RAE5	Phosphatidylinositol 3-kinase catalytic subunit type 3. (885 aa)
	A0A182RAN7	Uncharacterized protein. (246 aa)
	A0A182RC14	Uncharacterized protein. (127 aa)
	A0A182RCN6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (646 aa)
	A0A182RCW2	P53 domain-containing protein. (440 aa)
	A0A182RD46	Uncharacterized protein. (1419 aa)
	A0A182RDM4	Uncharacterized protein. (167 aa)
	A0A182RDS8	Uncharacterized protein. (212 aa)
	A0A182RE98	Uncharacterized protein. (661 aa)
	A0A182REU6	Uncharacterized protein. (228 aa)
	A0A182REV6	Protein kinase domain-containing protein. (1366 aa)
	A0A182RF80	Uncharacterized protein; Belongs to the AAA ATPase family. (804 aa)
	A0A182RFR2	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (349 aa)
	A0A182RQF9	PP1c_bdg domain-containing protein. (508 aa)
	A0A182RQJ2	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
	A0A182RR75	Uncharacterized protein. (603 aa)
	A0A182RTH0	Uncharacterized protein. (1048 aa)
	A0A182RTP0	PRA1 family protein. (191 aa)
	A0A182RUX7	Uncharacterized protein. (494 aa)
	A0A182RV26	Uncharacterized protein. (1208 aa)
	A0A182RWL5	Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (930 aa)
	A0A182RWN5	Uncharacterized protein. (483 aa)
	A0A182RWY3	Uncharacterized protein. (590 aa)
	A0A182RYF5	Pep_M12B_propep domain-containing protein. (354 aa)
	A0A182RZ67	Protein kinase domain-containing protein. (742 aa)
	A0A182RZC5	Uncharacterized protein. (2962 aa)
	A0A1I8JUR6	Uncharacterized protein. (352 aa)
	A0A1Y9HAA5	Merlin (moesin-ezrin-radixin-like protein). (585 aa)
	A0A1Y9HF07	Tyrosine-protein kinase. (1272 aa)
	A0A182RG40	Uncharacterized protein. (1284 aa)
	A0A182RG44	Uncharacterized protein. (2051 aa)
	A0A182RGB3	Mitogen-activated protein kinase. (387 aa)
	A0A182RGB4	Mitogen-activated protein kinase. (376 aa)
	A0A182RHI1	SAP domain-containing protein. (1336 aa)
	A0A182RHT2	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (692 aa)
	A0A182RIL2	Uncharacterized protein. (803 aa)
	A0A182RJK7	UBIQUITIN_CONJUGAT_2 domain-containing protein. (143 aa)
	A0A182RJN2	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (333 aa)
	A0A182RKR9	Uncharacterized protein. (179 aa)
	A0A182RL27	Uncharacterized protein. (1411 aa)
	A0A182RLK4	Uncharacterized protein. (99 aa)
	A0A182RM02	Uncharacterized protein. (392 aa)
	A0A182RM62	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (380 aa)
	A0A182RMT7	Uncharacterized protein; Belongs to the peptidase C14A family. (313 aa)
	A0A182RMV5	Uncharacterized protein. (888 aa)
	A0A182RNM9	Uncharacterized protein. (845 aa)
	A0A182RNS2	Uncharacterized protein. (381 aa)
	A0A182RNT5	Uncharacterized protein. (193 aa)
	A0A182RPM6	Protein kinase domain-containing protein. (558 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R1G8	A0A182R1J4	Protein kinase domain-containing protein.	GTP-binding protein Rheb.	0.485
A0A182R1G8	A0A182R9A7	Protein kinase domain-containing protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.540
A0A182R1G8	A0A182RD46	Protein kinase domain-containing protein.	Uncharacterized protein.	0.586
A0A182R1G8	A0A182RGB3	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.991
A0A182R1G8	A0A182RGB4	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.991
A0A182R1G8	A0A182RM02	Protein kinase domain-containing protein.	Uncharacterized protein.	0.574
A0A182R1G8	A0A182RNS2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.664
A0A182R1G8	A0A182RPM6	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.578
A0A182R1G8	A0A182RWN5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.672
A0A182R1G8	A0A1Y9HF07	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.526
A0A182R1G8	A0A4Y0B9Y4	Protein kinase domain-containing protein.	Uncharacterized protein.	0.672
A0A182R1G8	A0A4Y0BDI4	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.518
A0A182R1G8	A0A4Y0BLS2	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.894
A0A182R1G8	A0A4Y0BLU7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.454
A0A182R1G8	A0A4Y0BMS8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.454
A0A182R1G8	A0A4Y0BRZ0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.454
A0A182R1J4	A0A182R1G8	GTP-binding protein Rheb.	Protein kinase domain-containing protein.	0.485
A0A182R1J4	A0A182R5H7	GTP-binding protein Rheb.	Uncharacterized protein.	0.965
A0A182R1J4	A0A182R919	GTP-binding protein Rheb.	Merlin (moesin-ezrin-radixin-like protein).	0.401
A0A182R1J4	A0A182RAE5	GTP-binding protein Rheb.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.599