(12 nodes) Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen network (Anopheles funestus)

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	A0A182S539	Uncharacterized protein; Belongs to the cytochrome P450 family. (512 aa)
	A0A182S538	Cytochrome P450; Belongs to the cytochrome P450 family. (497 aa)
	A0A182RZP9	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (485 aa)
	A0A182RFA6	Cytochrome P450; Belongs to the cytochrome P450 family. (505 aa)
	A0A182RCI8	Uncharacterized protein. (3135 aa)
	A0A182R8W8	Flavin-containing monooxygenase. (425 aa)
	A0A182R8W7	Flavin-containing monooxygenase. (417 aa)
	A0A182R8W6	Flavin-containing monooxygenase. (432 aa)
	A0A182R8W5	Flavin-containing monooxygenase. (444 aa)
	coq6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (474 aa)
	A0A4Y0AT89	Uncharacterized protein. (1581 aa)
	A0A4Y0BMI3	Nitric oxide synthase; Produces nitric oxide (NO). (1312 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A182R8W5	A0A182RZP9	A0A182R8W5	A0A182RZP9	Flavin-containing monooxygenase.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.659
A0A182R8W5	coq6	A0A182R8W5	A0A4Y0BNU4	Flavin-containing monooxygenase.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.657
A0A182R8W6	A0A182RZP9	A0A182R8W6	A0A182RZP9	Flavin-containing monooxygenase.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.659
A0A182R8W6	coq6	A0A182R8W6	A0A4Y0BNU4	Flavin-containing monooxygenase.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.657
A0A182R8W7	A0A182RZP9	A0A182R8W7	A0A182RZP9	Flavin-containing monooxygenase.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.659
A0A182R8W7	coq6	A0A182R8W7	A0A4Y0BNU4	Flavin-containing monooxygenase.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.657
A0A182R8W8	A0A182RZP9	A0A182R8W8	A0A182RZP9	Flavin-containing monooxygenase.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.659
A0A182R8W8	coq6	A0A182R8W8	A0A4Y0BNU4	Flavin-containing monooxygenase.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.657
A0A182RFA6	A0A182RZP9	A0A182RFA6	A0A182RZP9	Cytochrome P450; Belongs to the cytochrome P450 family.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.489
A0A182RFA6	A0A182S538	A0A182RFA6	A0A182S538	Cytochrome P450; Belongs to the cytochrome P450 family.	Cytochrome P450; Belongs to the cytochrome P450 family.	0.712
A0A182RFA6	A0A182S539	A0A182RFA6	A0A182S539	Cytochrome P450; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.697
A0A182RFA6	A0A4Y0BMI3	A0A182RFA6	A0A4Y0BMI3	Cytochrome P450; Belongs to the cytochrome P450 family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.483
A0A182RFA6	coq6	A0A182RFA6	A0A4Y0BNU4	Cytochrome P450; Belongs to the cytochrome P450 family.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.414
A0A182RZP9	A0A182R8W5	A0A182RZP9	A0A182R8W5	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Flavin-containing monooxygenase.	0.659
A0A182RZP9	A0A182R8W6	A0A182RZP9	A0A182R8W6	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Flavin-containing monooxygenase.	0.659
A0A182RZP9	A0A182R8W7	A0A182RZP9	A0A182R8W7	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Flavin-containing monooxygenase.	0.659
A0A182RZP9	A0A182R8W8	A0A182RZP9	A0A182R8W8	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Flavin-containing monooxygenase.	0.659
A0A182RZP9	A0A182RFA6	A0A182RZP9	A0A182RFA6	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Cytochrome P450; Belongs to the cytochrome P450 family.	0.489
A0A182RZP9	A0A182S538	A0A182RZP9	A0A182S538	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Cytochrome P450; Belongs to the cytochrome P450 family.	0.489
A0A182RZP9	A0A182S539	A0A182RZP9	A0A182S539	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.489