(19 nodes) Cytokine-mediated signaling pathway network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182RNB0	TOLL pathway signalling Ser/Thr kinase. (506 aa)
	A0A182RM62	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (380 aa)
	A0A182RHM2	TRAF-type domain-containing protein. (383 aa)
	A0A182RGB4	Mitogen-activated protein kinase. (376 aa)
	A0A182RGB3	Mitogen-activated protein kinase. (387 aa)
	A0A182RDS8	Uncharacterized protein. (212 aa)
	A0A182RDN9	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1143 aa)
	A0A182RD46	Uncharacterized protein. (1419 aa)
	A0A182R9A7	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (515 aa)
	A0A182R1P4	Uncharacterized protein. (1162 aa)
	A0A182R1G8	Protein kinase domain-containing protein. (1128 aa)
	A0A182RWS0	Uncharacterized protein. (1509 aa)
	A0A182RNS2	Uncharacterized protein. (381 aa)
	A0A4Y0BLS2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (392 aa)
	A0A4Y0B8G1	Uncharacterized protein. (757 aa)
	A0A453YNH5	FAD-binding FR-type domain-containing protein. (392 aa)
	A0A182RZK7	Uncharacterized protein. (425 aa)
	A0A182RYF5	Pep_M12B_propep domain-containing protein. (354 aa)
	A0A182RXZ9	Protein kinase domain-containing protein. (690 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R1G8	A0A182R9A7	Protein kinase domain-containing protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.540
A0A182R1G8	A0A182RD46	Protein kinase domain-containing protein.	Uncharacterized protein.	0.586
A0A182R1G8	A0A182RDN9	Protein kinase domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.568
A0A182R1G8	A0A182RGB3	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.991
A0A182R1G8	A0A182RGB4	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.991
A0A182R1G8	A0A182RHM2	Protein kinase domain-containing protein.	TRAF-type domain-containing protein.	0.797
A0A182R1G8	A0A182RNB0	Protein kinase domain-containing protein.	TOLL pathway signalling Ser/Thr kinase.	0.684
A0A182R1G8	A0A182RNS2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.664
A0A182R1G8	A0A182RXZ9	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.623
A0A182R1G8	A0A4Y0BLS2	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.894
A0A182R1P4	A0A182RDN9	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.896
A0A182R9A7	A0A182R1G8	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Protein kinase domain-containing protein.	0.540
A0A182R9A7	A0A182RDS8	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.917
A0A182R9A7	A0A182RGB3	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Mitogen-activated protein kinase.	0.752
A0A182R9A7	A0A182RGB4	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Mitogen-activated protein kinase.	0.752
A0A182R9A7	A0A182RNS2	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.571
A0A182RD46	A0A182R1G8	Uncharacterized protein.	Protein kinase domain-containing protein.	0.586
A0A182RD46	A0A182RHM2	Uncharacterized protein.	TRAF-type domain-containing protein.	0.600
A0A182RD46	A0A182RNS2	Uncharacterized protein.	Uncharacterized protein.	0.818
A0A182RDN9	A0A182R1G8	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Protein kinase domain-containing protein.	0.568