51 items (Anopheles funestus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182R393	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
	A0A182R3P5	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (1089 aa)
	A0A182R410	Mcm10 domain-containing protein. (794 aa)
	A0A182R440	Uncharacterized protein. (1391 aa)
	A0A182R441	Uncharacterized protein. (90 aa)
	A0A182R601	Uncharacterized protein. (633 aa)
	A0A182R6R4	Myb_DNA-bind_5 domain-containing protein. (282 aa)
	A0A182R829	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1448 aa)
	A0A182R8E4	RECA_2 domain-containing protein. (262 aa)
	A0A182R8G5	Uncharacterized protein. (1444 aa)
	A0A182R8K6	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (736 aa)
	A0A182R9V6	Cnd1 domain-containing protein. (1300 aa)
	A0A182RB00	Uncharacterized protein. (7635 aa)
	A0A182RCF7	AAA_16 domain-containing protein. (464 aa)
	A0A182RCR4	Uncharacterized protein. (727 aa)
	A0A182RD00	Uncharacterized protein. (208 aa)
	A0A182RD83	Protein kinase domain-containing protein. (645 aa)
	A0A182RFD0	Structural maintenance of chromosomes protein. (1190 aa)
	A0A182RFS0	Cnd3 domain-containing protein. (1316 aa)
	A0A182RGE8	Uncharacterized protein; Belongs to the argonaute family. (892 aa)
	A0A182RHU0	Uncharacterized protein. (718 aa)
	A0A182RI25	DNA helicase; Belongs to the MCM family. (733 aa)
	A0A182RIR3	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1530 aa)
	A0A182RN62	Uncharacterized protein. (1293 aa)
	A0A182RNC1	Leishmanolysin-like peptidase. (720 aa)
	A0A182RNW9	CNDH2_C domain-containing protein. (1151 aa)
	A0A182RQR6	MBD domain-containing protein. (303 aa)
	A0A182RR67	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (492 aa)
	A0A182RSA0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2649 aa)
	A0A182RSK1	Uncharacterized protein. (755 aa)
	A0A182RTS2	BCNT-C domain-containing protein. (288 aa)
	A0A182RUV4	Uncharacterized protein. (668 aa)
	A0A182RVL1	Structural maintenance of chromosomes protein. (1391 aa)
	A0A182RWN4	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (205 aa)
	A0A182RX78	DNA helicase; Belongs to the MCM family. (899 aa)
	A0A182RXT7	Uncharacterized protein. (569 aa)
	A0A182RYZ7	RING-type domain-containing protein. (1198 aa)
	A0A182RZN3	Myb_DNA-bind_5 domain-containing protein. (99 aa)
	A0A182S087	Myb_DNA-bind_5 domain-containing protein. (207 aa)
	A0A182S4N0	SLBP_RNA_bind domain-containing protein. (260 aa)
	A0A4Y0API6	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1454 aa)
	A0A4Y0BDQ7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2661 aa)
	A0A4Y0BE79	Cnd3 domain-containing protein. (1435 aa)
	A0A4Y0BGG1	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1228 aa)
	A0A4Y0BGU3	Uncharacterized protein. (1144 aa)
	A0A4Y0BH52	Uncharacterized protein. (718 aa)
	A0A4Y0BHH1	Uncharacterized protein. (1119 aa)
	A0A4Y0BI55	Uncharacterized protein. (553 aa)
	A0A4Y0BIV3	Uncharacterized protein. (7591 aa)
	A0A4Y0BJK3	Uncharacterized protein. (725 aa)
	A0A4Y0BK12	Uncharacterized protein. (968 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R393	A0A182R410	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mcm10 domain-containing protein.	0.413
A0A182R393	A0A182R829	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	0.606
A0A182R393	A0A182R8K6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.	0.870
A0A182R393	A0A182R9V6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cnd1 domain-containing protein.	0.496
A0A182R393	A0A182RD00	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.698
A0A182R393	A0A182RD83	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.450
A0A182R393	A0A182RFD0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Structural maintenance of chromosomes protein.	0.799
A0A182R393	A0A182RFS0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cnd3 domain-containing protein.	0.648
A0A182R393	A0A182RI25	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DNA helicase; Belongs to the MCM family.	0.561
A0A182R393	A0A182RIR3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.698
A0A182R393	A0A182RQR6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	MBD domain-containing protein.	0.487
A0A182R393	A0A182RUV4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.711
A0A182R393	A0A182RVL1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Structural maintenance of chromosomes protein.	0.701
A0A182R393	A0A182RX78	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DNA helicase; Belongs to the MCM family.	0.667
A0A182R393	A0A182RXT7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.593
A0A182R393	A0A4Y0API6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	0.606
A0A182R393	A0A4Y0BE79	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cnd3 domain-containing protein.	0.648
A0A182R3P5	A0A182R410	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	Mcm10 domain-containing protein.	0.529
A0A182R3P5	A0A182R8E4	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	RECA_2 domain-containing protein.	0.535
A0A182R3P5	A0A182RD00	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	Uncharacterized protein.	0.940