(56 nodes) Tube formation network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4Y0BLL2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (428 aa)
	A0A4Y0BLG1	Uncharacterized protein. (134 aa)
	A0A4Y0BLB1	Uncharacterized protein. (89 aa)
	A0A4Y0BL82	Uncharacterized protein. (7397 aa)
	A0A4Y0BKK7	Uncharacterized protein. (2928 aa)
	A0A4Y0BKG1	T-complex protein 1 subunit gamma. (548 aa)
	A0A4Y0BJW0	Uncharacterized protein. (8410 aa)
	A0A4Y0BJV9	Uncharacterized protein. (986 aa)
	A0A4Y0BJ07	Vitellogenin domain-containing protein. (877 aa)
	A0A4Y0BIE4	KASH domain-containing protein. (2158 aa)
	A0A4Y0BI11	Microtubule-associated protein. (340 aa)
	A0A4Y0BI09	Uncharacterized protein. (7433 aa)
	A0A4Y0BI06	ZnMc domain-containing protein. (476 aa)
	A0A4Y0BHG8	CTCK domain-containing protein. (281 aa)
	A0A4Y0BHE4	Uncharacterized protein. (711 aa)
	A0A4Y0BH65	Microtubule-associated protein. (860 aa)
	A0A4Y0BGW3	Uncharacterized protein. (1110 aa)
	A0A4Y0BGN0	Homeobox protein cut-like. (2097 aa)
	A0A4Y0BG18	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (779 aa)
	A0A4Y0BFL2	Microtubule-associated protein. (304 aa)
	A0A4Y0BFF8	Uncharacterized protein. (1172 aa)
	A0A4Y0BEG3	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (773 aa)
	A0A4Y0B947	CAP-Gly domain-containing protein. (1263 aa)
	A0A4Y0B2U4	Uncharacterized protein. (4256 aa)
	A0A4Y0B206	Receptor protein-tyrosine kinase. (1488 aa)
	A0A4Y0ANC7	Uncharacterized protein. (4665 aa)
	A0A1I8JUH7	Uncharacterized protein. (128 aa)
	A0A182S043	CAP-Gly domain-containing protein. (1215 aa)
	A0A182RXJ8	Rab-GAP TBC domain-containing protein. (392 aa)
	A0A182RW78	Uncharacterized protein. (1105 aa)
	A0A182RSY6	T-complex protein 1 subunit gamma. (548 aa)
	A0A182RRK0	Uncharacterized protein. (404 aa)
	A0A182RQC8	Uncharacterized protein. (4398 aa)
	A0A182RPP5	Receptor protein-tyrosine kinase. (1465 aa)
	A0A182RPD0	Uncharacterized protein. (1637 aa)
	A0A182RNT9	Uncharacterized protein. (657 aa)
	A0A182RNP9	Uncharacterized protein. (202 aa)
	A0A182RM16	SAC domain-containing protein. (590 aa)
	A0A182RJH8	ZnMc domain-containing protein. (547 aa)
	A0A182RIV1	WD_REPEATS_REGION domain-containing protein. (3507 aa)
	A0A182RGX5	VHL domain-containing protein. (151 aa)
	A0A182RG51	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (298 aa)
	A0A182RES1	Uncharacterized protein. (620 aa)
	A0A182RE39	Uncharacterized protein. (711 aa)
	A0A182RBQ5	Uncharacterized protein. (484 aa)
	A0A182R6C1	Uncharacterized protein. (3347 aa)
	A0A182R5X2	Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (211 aa)
	A0A182R4X8	SEC7 domain-containing protein. (2096 aa)
	A0A182R3G4	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (516 aa)
	A0A4Y0BUQ9	Uncharacterized protein. (477 aa)
	A0A4Y0BRV6	Uncharacterized protein. (207 aa)
	A0A4Y0BQB5	Uncharacterized protein. (8719 aa)
	A0A4Y0BMD0	KASH domain-containing protein. (1661 aa)
	A0A4Y0BLW1	ZnMc domain-containing protein. (317 aa)
	A0A4Y0BLS3	Uncharacterized protein. (192 aa)
	A0A4Y0BLN0	Uncharacterized protein. (1473 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R3G4	A0A182R6C1	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Uncharacterized protein.	0.924
A0A182R3G4	A0A182S043	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	CAP-Gly domain-containing protein.	0.919
A0A182R3G4	A0A4Y0ANC7	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Uncharacterized protein.	0.924
A0A182R3G4	A0A4Y0B947	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	CAP-Gly domain-containing protein.	0.919
A0A182R4X8	A0A182R6C1	SEC7 domain-containing protein.	Uncharacterized protein.	0.510
A0A182R4X8	A0A182S043	SEC7 domain-containing protein.	CAP-Gly domain-containing protein.	0.594
A0A182R4X8	A0A4Y0ANC7	SEC7 domain-containing protein.	Uncharacterized protein.	0.510
A0A182R4X8	A0A4Y0B947	SEC7 domain-containing protein.	CAP-Gly domain-containing protein.	0.594
A0A182R4X8	A0A4Y0BLS3	SEC7 domain-containing protein.	Uncharacterized protein.	0.663
A0A182R4X8	A0A4Y0BRV6	SEC7 domain-containing protein.	Uncharacterized protein.	0.663
A0A182R5X2	A0A4Y0BEG3	Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.794
A0A182R5X2	A0A4Y0BG18	Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.794
A0A182R5X2	A0A4Y0BGW3	Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.	Uncharacterized protein.	0.732
A0A182R5X2	A0A4Y0BJV9	Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.	Uncharacterized protein.	0.732
A0A182R6C1	A0A182R3G4	Uncharacterized protein.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.924
A0A182R6C1	A0A182R4X8	Uncharacterized protein.	SEC7 domain-containing protein.	0.510
A0A182R6C1	A0A182RG51	Uncharacterized protein.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.924
A0A182R6C1	A0A182S043	Uncharacterized protein.	CAP-Gly domain-containing protein.	0.857
A0A182R6C1	A0A4Y0B947	Uncharacterized protein.	CAP-Gly domain-containing protein.	0.857
A0A182R6C1	A0A4Y0BLG1	Uncharacterized protein.	Uncharacterized protein.	0.510