10 items (Anopheles funestus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4Y0BLN2	PINc domain-containing protein. (1563 aa)
	A0A4Y0BQ50	Ku domain-containing protein. (728 aa)
	A0A4Y0B5Z4	Uncharacterized protein. (116 aa)
	A0A4Y0AV06	BRCT domain-containing protein. (1575 aa)
	A0A182RTH7	Ku domain-containing protein. (622 aa)
	A0A182RRS7	Zinc-hook domain-containing protein. (1308 aa)
	A0A182RRB4	Uncharacterized protein. (141 aa)
	A0A182RPL3	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
	A0A182RGT1	TM2 domain-containing protein. (254 aa)
	A0A182RCP5	Uncharacterized protein. (1151 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182RCP5	A0A182RRB4	Uncharacterized protein.	Uncharacterized protein.	0.558
A0A182RCP5	A0A182RTH7	Uncharacterized protein.	Ku domain-containing protein.	0.737
A0A182RCP5	A0A4Y0B5Z4	Uncharacterized protein.	Uncharacterized protein.	0.558
A0A182RCP5	A0A4Y0BLN2	Uncharacterized protein.	PINc domain-containing protein.	0.946
A0A182RCP5	A0A4Y0BQ50	Uncharacterized protein.	Ku domain-containing protein.	0.558
A0A182RGT1	A0A182RRS7	TM2 domain-containing protein.	Zinc-hook domain-containing protein.	0.415
A0A182RPL3	A0A182RRB4	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Uncharacterized protein.	0.477
A0A182RPL3	A0A182RRS7	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Zinc-hook domain-containing protein.	0.902
A0A182RPL3	A0A182RTH7	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Ku domain-containing protein.	0.928
A0A182RPL3	A0A4Y0AV06	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	BRCT domain-containing protein.	0.877
A0A182RPL3	A0A4Y0B5Z4	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Uncharacterized protein.	0.477
A0A182RPL3	A0A4Y0BQ50	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Ku domain-containing protein.	0.477
A0A182RRB4	A0A182RCP5	Uncharacterized protein.	Uncharacterized protein.	0.558
A0A182RRB4	A0A182RPL3	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.477
A0A182RRB4	A0A182RRS7	Uncharacterized protein.	Zinc-hook domain-containing protein.	0.800
A0A182RRB4	A0A182RTH7	Uncharacterized protein.	Ku domain-containing protein.	0.974
A0A182RRB4	A0A4Y0AV06	Uncharacterized protein.	BRCT domain-containing protein.	0.707
A0A182RRB4	A0A4Y0BLN2	Uncharacterized protein.	PINc domain-containing protein.	0.558
A0A182RRS7	A0A182RGT1	Zinc-hook domain-containing protein.	TM2 domain-containing protein.	0.415
A0A182RRS7	A0A182RPL3	Zinc-hook domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.902