(46 nodes) Glucose homeostasis network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182R219	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1171 aa)
	A0A182RZK7	Uncharacterized protein. (425 aa)
	A0A182RZ64	PWWP domain-containing protein. (1468 aa)
	A0A182RYR2	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (482 aa)
	A0A182RXC7	Glucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
	A0A182RX75	G_PROTEIN_RECEP_F3_4 domain-containing protein. (1062 aa)
	A0A182RVL0	Enolase. (433 aa)
	A0A182RRU9	Uncharacterized protein; Belongs to the peptidase S1 family. (1295 aa)
	A0A182RR76	Nudix hydrolase domain-containing protein. (226 aa)
	A0A182RPM6	Protein kinase domain-containing protein. (558 aa)
	A0A182RN70	Uncharacterized protein. (576 aa)
	A0A182RN69	G_PROTEIN_RECEP_F1_2 domain-containing protein. (354 aa)
	A0A182RLF4	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (201 aa)
	A0A182RHL6	TUG-UBL1 domain-containing protein. (497 aa)
	A0A182RH81	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
	A0A182RFP8	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (789 aa)
	A0A182REX0	Mothers against decapentaplegic homolog. (512 aa)
	A0A182RDA6	Uncharacterized protein. (650 aa)
	A0A182RCY8	Phosphotransferase. (463 aa)
	A0A182R653	Uncharacterized protein. (401 aa)
	A0A182R4X2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (597 aa)
	A0A4Y0BKL1	Protein kinase domain-containing protein. (132 aa)
	A0A4Y0BK68	Rab-GAP TBC domain-containing protein. (296 aa)
	A0A4Y0BK50	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (647 aa)
	A0A4Y0BLJ8	Uncharacterized protein. (2200 aa)
	A0A4Y0BLP2	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (1928 aa)
	A0A4Y0BM24	Uncharacterized protein. (2577 aa)
	A0A4Y0BM78	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (206 aa)
	A0A4Y0BMW2	UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (1105 aa)
	A0A4Y0BN65	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (1759 aa)
	A0A4Y0BPL3	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (231 aa)
	A0A4Y0BPL8	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (208 aa)
	A0A4Y0BQP9	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (234 aa)
	A0A4Y0BV43	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (199 aa)
	A0A4Y0BJP6	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (1859 aa)
	A0A4Y0BJN2	BHLH domain-containing protein. (1318 aa)
	A0A4Y0BIN2	Protein kinase domain-containing protein. (513 aa)
	A0A4Y0BIA6	Uncharacterized protein. (519 aa)
	A0A4Y0AXI8	MH2 domain-containing protein. (267 aa)
	A0A4Y0AW19	Phosphotransferase. (455 aa)
	A0A4Y0ATV2	Phosphotransferase. (452 aa)
	A0A1Y9HCG0	Enolase. (441 aa)
	A0A1Y9HAX6	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (789 aa)
	A0A1Y9HAX5	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (789 aa)
	A0A1I8JU43	Phosphotransferase. (454 aa)
	A0A182S506	Adipokinetic hormone 1. (79 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R219	A0A182R4X2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.535
A0A182R219	A0A182R653	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.840
A0A182R219	A0A182RH81	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.639
A0A182R219	A0A182RN69	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.535
A0A182R219	A0A182RPM6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.461
A0A182R219	A0A4Y0BIA6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.442
A0A182R219	A0A4Y0BK50	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.525
A0A182R219	A0A4Y0BLJ8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.919
A0A182R219	A0A4Y0BM24	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.919
A0A182R4X2	A0A182R219	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.535
A0A182R4X2	A0A182RN69	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.913
A0A182R4X2	A0A182S506	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Adipokinetic hormone 1.	0.518
A0A182R4X2	A0A4Y0BMW2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family.	0.436
A0A182R653	A0A182R219	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.840
A0A182R653	A0A182RDA6	Uncharacterized protein.	Uncharacterized protein.	0.688
A0A182R653	A0A182REX0	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.766
A0A182R653	A0A182RH81	Uncharacterized protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.554
A0A182R653	A0A182RN70	Uncharacterized protein.	Uncharacterized protein.	0.547
A0A182R653	A0A182RPM6	Uncharacterized protein.	Protein kinase domain-containing protein.	0.955
A0A182R653	A0A4Y0AXI8	Uncharacterized protein.	MH2 domain-containing protein.	0.766