(87 nodes) Regulation of neuron differentiation network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182RCG2	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (110 aa)
	A0A182RC86	DUF3677 domain-containing protein. (2151 aa)
	A0A182RAX6	C2H2-type domain-containing protein. (380 aa)
	A0A182RAP6	Uncharacterized protein. (1748 aa)
	A0A182RAD2	Uncharacterized protein. (988 aa)
	A0A182R8B9	Uncharacterized protein. (891 aa)
	A0A182R6C1	Uncharacterized protein. (3347 aa)
	A0A182R6A7	Uncharacterized protein. (2460 aa)
	A0A182R5P0	P53 domain-containing protein. (399 aa)
	A0A182R410	Mcm10 domain-containing protein. (794 aa)
	A0A182R2W3	Uncharacterized protein. (685 aa)
	A0A182R2V0	Uncharacterized protein. (502 aa)
	A0A182R219	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1171 aa)
	A0A182R1H2	Uncharacterized protein. (184 aa)
	A0A2C9GWQ5	Uncharacterized protein. (873 aa)
	A0A3F2YXP8	Uncharacterized protein. (2757 aa)
	A0A4Y0ANC7	Uncharacterized protein. (4665 aa)
	A0A182RU55	PID domain-containing protein. (2433 aa)
	A0A182RW64	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1218 aa)
	A0A182RX01	HMG box domain-containing protein. (731 aa)
	A0A182RXK6	Uncharacterized protein. (600 aa)
	A0A182RYH5	Protein kinase domain-containing protein. (1234 aa)
	A0A182RYR8	Uncharacterized protein. (821 aa)
	A0A4Y0AQ35	Uncharacterized protein. (812 aa)
	A0A4Y0AT89	Uncharacterized protein. (1581 aa)
	A0A4Y0BH61	MFS domain-containing protein. (565 aa)
	A0A4Y0AWZ5	Uncharacterized protein. (886 aa)
	A0A4Y0BC71	Uncharacterized protein. (738 aa)
	A0A4Y0B5D8	PID domain-containing protein. (2435 aa)
	A0A4Y0BH14	Uncharacterized protein. (931 aa)
	A0A4Y0BGX9	Uncharacterized protein; Belongs to the DOCK family. (2096 aa)
	A0A4Y0BGP8	Uncharacterized protein. (548 aa)
	A0A4Y0BG23	Homeobox domain-containing protein. (454 aa)
	A0A4Y0BFM6	Uncharacterized protein. (4685 aa)
	A0A4Y0BIM0	Uncharacterized protein. (4684 aa)
	A0A4Y0BIM3	Protein kinase domain-containing protein. (1451 aa)
	A0A4Y0BIR6	Uncharacterized protein. (1270 aa)
	A0A4Y0BJ00	Uncharacterized protein. (1262 aa)
	A0A4Y0BJ12	Tyrosine-protein kinase. (508 aa)
	A0A4Y0BJ45	Uncharacterized protein. (711 aa)
	A0A4Y0BKQ6	Uncharacterized protein. (853 aa)
	A0A4Y0BLM4	Uncharacterized protein. (776 aa)
	A0A4Y0BLZ2	Uncharacterized protein. (4424 aa)
	A0A4Y0BM07	Uncharacterized protein. (727 aa)
	A0A4Y0BM32	Protein kinase domain-containing protein. (1063 aa)
	A0A4Y0BMA7	Prospero domain-containing protein. (1821 aa)
	A0A4Y0BMK3	Uncharacterized protein. (884 aa)
	A0A4Y0BN81	Homeobox domain-containing protein. (515 aa)
	A0A4Y0BNL9	Uncharacterized protein. (998 aa)
	A0A4Y0BPJ6	Uncharacterized protein. (1294 aa)
	A0A4Y0BR46	Uncharacterized protein. (680 aa)
	A0A4Y0BR74	Protein kinase domain-containing protein. (903 aa)
	A0A4Y0BRP9	ETS domain-containing protein. (579 aa)
	A0A4Y0BRY7	Uncharacterized protein. (1677 aa)
	A0A4Y0BWL9	Uncharacterized protein. (1701 aa)
	A0A4Y0BFK7	MFS domain-containing protein. (512 aa)
	A0A4Y0BE60	Uncharacterized protein. (124 aa)
	A0A182RYW6	Non-specific serine/threonine protein kinase. (869 aa)
	A0A182RZ48	Paired domain-containing protein. (525 aa)
	A0A182RZR5	ANK_REP_REGION domain-containing protein. (90 aa)
	A0A1I8JUS5	Nicastrin. (719 aa)
	A0A4Y0BID7	Uncharacterized protein. (769 aa)
	A0A182RSJ4	SEC7 domain-containing protein. (1837 aa)
	A0A182RR67	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (492 aa)
	A0A182RR66	Tyrosine-protein kinase. (537 aa)
	A0A182RQY7	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (306 aa)
	A0A182RQ13	Uncharacterized protein. (667 aa)
	A0A182RPM8	Uncharacterized protein. (1001 aa)
	A0A182RPJ4	Uncharacterized protein. (2310 aa)
	A0A4Y0BH85	Uncharacterized protein. (1552 aa)
	A0A182RNP3	Uncharacterized protein. (935 aa)
	A0A182RNN3	Non-specific serine/threonine protein kinase. (588 aa)
	A0A182RM89	CBFD_NFYB_HMF domain-containing protein. (178 aa)
	A0A182RLS8	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (643 aa)
	A0A182RLS7	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (478 aa)
	A0A182RLE6	Uncharacterized protein. (519 aa)
	A0A182RL34	Uncharacterized protein. (272 aa)
	A0A182RIY9	BEN domain-containing protein. (533 aa)
	A0A182RHM6	Uncharacterized protein. (885 aa)
	A0A182RH78	Zn-C2H2_12 domain-containing protein. (381 aa)
	A0A182RH59	Uncharacterized protein. (981 aa)
	A0A182RGR4	Uncharacterized protein. (944 aa)
	A0A182RGB4	Mitogen-activated protein kinase. (376 aa)
	A0A182RGB3	Mitogen-activated protein kinase. (387 aa)
	A0A182RG65	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (395 aa)
	A0A182RF60	USP domain-containing protein; Belongs to the peptidase C19 family. (1382 aa)
	A0A182RCI8	Uncharacterized protein. (3135 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R1H2	A0A182R219	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.873
A0A182R1H2	A0A182R2W3	Uncharacterized protein.	Uncharacterized protein.	0.987
A0A182R1H2	A0A182RAP6	Uncharacterized protein.	Uncharacterized protein.	0.662
A0A182R1H2	A0A182RG65	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.537
A0A182R1H2	A0A182RGB3	Uncharacterized protein.	Mitogen-activated protein kinase.	0.751
A0A182R1H2	A0A182RGB4	Uncharacterized protein.	Mitogen-activated protein kinase.	0.751
A0A182R1H2	A0A182RH59	Uncharacterized protein.	Uncharacterized protein.	0.702
A0A182R1H2	A0A182RLS7	Uncharacterized protein.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.439
A0A182R1H2	A0A182RLS8	Uncharacterized protein.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.439
A0A182R1H2	A0A182RNN3	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.452
A0A182R1H2	A0A182RR66	Uncharacterized protein.	Tyrosine-protein kinase.	0.718
A0A182R1H2	A0A182RSJ4	Uncharacterized protein.	SEC7 domain-containing protein.	0.509
A0A182R1H2	A0A182RW64	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.519
A0A182R1H2	A0A182RYH5	Uncharacterized protein.	Protein kinase domain-containing protein.	0.419
A0A182R1H2	A0A182RYW6	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.686
A0A182R1H2	A0A182RZR5	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.428
A0A182R1H2	A0A4Y0BFM6	Uncharacterized protein.	Uncharacterized protein.	0.483
A0A182R1H2	A0A4Y0BGP8	Uncharacterized protein.	Uncharacterized protein.	0.543
A0A182R1H2	A0A4Y0BGX9	Uncharacterized protein.	Uncharacterized protein; Belongs to the DOCK family.	0.580
A0A182R1H2	A0A4Y0BH85	Uncharacterized protein.	Uncharacterized protein.	0.718