(64 nodes) Regulation of JNK cascade network (Anopheles funestus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4Y0B8N3	Uncharacterized protein. (1234 aa)
	A0A4Y0AN43	Uncharacterized protein. (695 aa)
	A0A4Y0ALV6	Uncharacterized protein. (1238 aa)
	A0A182RYG5	Protein kinase domain-containing protein. (1573 aa)
	A0A182RY66	Battenin. (445 aa)
	A0A182RWN5	Uncharacterized protein. (483 aa)
	A0A182RWM8	Uncharacterized protein. (964 aa)
	A0A182RWL5	Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (930 aa)
	A0A182RUW5	Uncharacterized protein. (1237 aa)
	A0A182RTZ1	RING-type domain-containing protein. (528 aa)
	A0A182RT75	Uncharacterized protein. (417 aa)
	A0A182RQX4	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (289 aa)
	A0A182RPM6	Protein kinase domain-containing protein. (558 aa)
	A0A182RPF3	Uncharacterized protein. (544 aa)
	A0A182RP35	Uncharacterized protein. (410 aa)
	A0A182RNS2	Uncharacterized protein. (381 aa)
	A0A182RNE4	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (973 aa)
	A0A182RMB5	Protein kinase domain-containing protein. (90 aa)
	A0A182RM16	SAC domain-containing protein. (590 aa)
	A0A182RJK7	UBIQUITIN_CONJUGAT_2 domain-containing protein. (143 aa)
	A0A182RJC8	Uncharacterized protein. (504 aa)
	A0A182RIR0	BZIP domain-containing protein. (375 aa)
	A0A182RHM2	TRAF-type domain-containing protein. (383 aa)
	A0A182RGY1	Uncharacterized protein. (1494 aa)
	A0A182RGL7	Ubiquitin carboxyl-terminal hydrolase. (835 aa)
	A0A182RGE0	Uncharacterized protein. (272 aa)
	A0A182RG46	ELMO domain-containing protein. (722 aa)
	A0A182RG40	Uncharacterized protein. (1284 aa)
	A0A182RDS8	Uncharacterized protein. (212 aa)
	A0A182RDI4	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (483 aa)
	A0A182RCU6	Uncharacterized protein. (691 aa)
	A0A182RBT4	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (275 aa)
	A0A182RBP5	Uncharacterized protein. (892 aa)
	A0A182RAT7	Uncharacterized protein. (2933 aa)
	A0A182RAF6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	A0A182RA86	Uncharacterized protein. (289 aa)
	A0A182R8M6	Uncharacterized protein. (964 aa)
	A0A182R7L3	JmjC domain-containing protein. (407 aa)
	A0A182R5P1	Uncharacterized protein; Belongs to the DOCK family. (1087 aa)
	A0A182R465	Uncharacterized protein. (1015 aa)
	A0A182R2L5	Uncharacterized protein. (678 aa)
	A0A182R2J9	Receptor protein-tyrosine kinase. (1187 aa)
	A0A4Y0BTM6	Uncharacterized protein. (146 aa)
	A0A4Y0BR19	Protein kinase domain-containing protein. (1192 aa)
	A0A4Y0BPZ0	Uncharacterized protein. (734 aa)
	A0A4Y0BPT0	Uncharacterized protein. (2153 aa)
	A0A4Y0BPF5	Uncharacterized protein. (201 aa)
	A0A4Y0BPE6	BRO1 domain-containing protein. (850 aa)
	A0A4Y0BN09	N-acetyltransferase domain-containing protein. (203 aa)
	A0A4Y0BN04	Uncharacterized protein. (745 aa)
	A0A4Y0BMP5	Uncharacterized protein. (531 aa)
	A0A4Y0BM66	RING-type domain-containing protein. (328 aa)
	A0A4Y0BLX7	WD_REPEATS_REGION domain-containing protein. (755 aa)
	A0A4Y0BL73	Uncharacterized protein. (375 aa)
	A0A4Y0BJJ7	Protein kinase domain-containing protein. (1545 aa)
	A0A4Y0BJE7	Uncharacterized protein. (2594 aa)
	A0A4Y0BIP7	Uncharacterized protein. (574 aa)
	A0A4Y0BI27	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (370 aa)
	A0A4Y0BH04	Serine/threonine-protein phosphatase. (304 aa)
	A0A4Y0BFP8	LIM domain-containing protein. (347 aa)
	A0A4Y0BDY1	RING-type domain-containing protein. (329 aa)
	A0A4Y0BCM9	Uncharacterized protein. (544 aa)
	A0A4Y0B9Y4	Uncharacterized protein. (446 aa)
	A0A4Y0AXP6	BZIP domain-containing protein. (458 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R2J9	A0A182R2L5	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.508
A0A182R2J9	A0A182R5P1	Receptor protein-tyrosine kinase.	Uncharacterized protein; Belongs to the DOCK family.	0.626
A0A182R2J9	A0A182RG46	Receptor protein-tyrosine kinase.	ELMO domain-containing protein.	0.557
A0A182R2J9	A0A182RGE0	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.785
A0A182R2J9	A0A182RNS2	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.580
A0A182R2J9	A0A4Y0AN43	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.508
A0A182R2J9	A0A4Y0BI27	Receptor protein-tyrosine kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.573
A0A182R2J9	A0A4Y0BPF5	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.644
A0A182R2J9	A0A4Y0BTM6	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.644
A0A182R2L5	A0A182R2J9	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.508
A0A182R2L5	A0A182RMB5	Uncharacterized protein.	Protein kinase domain-containing protein.	0.508
A0A182R2L5	A0A4Y0BPF5	Uncharacterized protein.	Uncharacterized protein.	0.492
A0A182R2L5	A0A4Y0BTM6	Uncharacterized protein.	Uncharacterized protein.	0.492
A0A182R465	A0A182R5P1	Uncharacterized protein.	Uncharacterized protein; Belongs to the DOCK family.	0.436
A0A182R465	A0A182R8M6	Uncharacterized protein.	Uncharacterized protein.	0.490
A0A182R465	A0A182RAF6	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.401
A0A182R465	A0A182RDI4	Uncharacterized protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.654
A0A182R465	A0A182RG40	Uncharacterized protein.	Uncharacterized protein.	0.749
A0A182R465	A0A182RG46	Uncharacterized protein.	ELMO domain-containing protein.	0.537
A0A182R465	A0A182RGE0	Uncharacterized protein.	Uncharacterized protein.	0.549