(94 nodes) Positive regulation of immune response network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182R8U9	POU domain protein. (488 aa)
	A0A4Y0BP52	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
	A0A4Y0BNZ9	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (349 aa)
	A0A4Y0BNC0	LysM domain-containing protein. (1367 aa)
	A0A4Y0BN14	Uncharacterized protein. (451 aa)
	A0A4Y0BMX2	Uncharacterized protein. (840 aa)
	A0A4Y0BMW6	Uncharacterized protein. (657 aa)
	A0A4Y0BM24	Uncharacterized protein. (2577 aa)
	A0A4Y0BLY9	BTB domain-containing protein. (598 aa)
	A0A4Y0BLY4	Uncharacterized protein. (1170 aa)
	A0A4Y0BLY1	Uncharacterized protein. (665 aa)
	A0A4Y0BLW1	ZnMc domain-containing protein. (317 aa)
	A0A4Y0BLJ8	Uncharacterized protein. (2200 aa)
	A0A4Y0BLF8	Uncharacterized protein. (663 aa)
	A0A4Y0BLF2	Uncharacterized protein. (640 aa)
	A0A4Y0BLA0	Rad60-SLD domain-containing protein. (82 aa)
	A0A4Y0BKY2	Protein kinase domain-containing protein. (572 aa)
	A0A4Y0BKS5	HECT domain-containing protein. (1049 aa)
	A0A4Y0BKH9	Uncharacterized protein. (155 aa)
	A0A4Y0BK76	Protein kinase domain-containing protein. (1119 aa)
	A0A4Y0BJM3	TLDc domain-containing protein. (208 aa)
	A0A4Y0BJF7	Uncharacterized protein. (573 aa)
	A0A4Y0BJF1	BTB domain-containing protein. (686 aa)
	A0A182R1T2	Uncharacterized protein. (155 aa)
	A0A182R241	Small ubiquitin-related modifier. (93 aa)
	A0A182R532	Uncharacterized protein. (1645 aa)
	A0A182R5A9	TOLL-like receptor 7; Belongs to the Toll-like receptor family. (1327 aa)
	A0A182R6J6	Protein kinase domain-containing protein. (804 aa)
	A0A182RE56	Death domain-containing protein. (272 aa)
	A0A182REV7	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1855 aa)
	A0A182RG44	Uncharacterized protein. (2051 aa)
	A0A182RGE8	Uncharacterized protein; Belongs to the argonaute family. (892 aa)
	A0A182RGF4	RHD domain-containing protein. (680 aa)
	A0A182RHK2	Uncharacterized protein. (379 aa)
	A0A182RIC8	DNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (338 aa)
	A0A182RII9	Uncharacterized protein. (460 aa)
	A0A182RIM3	Small ubiquitin-related modifier. (94 aa)
	A0A182RIX6	Poly [ADP-ribose] polymerase. (1001 aa)
	A0A182RK53	SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. (661 aa)
	A0A182RK68	Uncharacterized protein. (415 aa)
	A0A182RLE3	Tr-type G domain-containing protein. (706 aa)
	A0A182RLK0	RING-type domain-containing protein. (212 aa)
	A0A182RNY9	Uncharacterized protein; Belongs to the peptidase S1 family. (667 aa)
	A0A182RRB4	Uncharacterized protein. (141 aa)
	A0A182RT42	ThiF domain-containing protein. (332 aa)
	A0A182RUJ8	Protein kinase domain-containing protein. (966 aa)
	A0A182RUV4	Uncharacterized protein. (668 aa)
	A0A182RVE3	WW domain-containing protein. (472 aa)
	A0A182RW08	RING-type domain-containing protein. (129 aa)
	A0A182RWR8	Uncharacterized protein. (866 aa)
	A0A182RY04	WD_REPEATS_REGION domain-containing protein. (1335 aa)
	A0A182RYX1	Aquaporin; Belongs to the MIP/aquaporin (TC 1.A.8) family. (262 aa)
	A0A182RZM0	Uncharacterized protein. (2003 aa)
	A0A182RZR2	CCHC NOA-type domain-containing protein. (546 aa)
	A0A182S069	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
	A0A182S133	SH2 domain-containing protein. (199 aa)
	A0A2C9GWR0	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (651 aa)
	A0A2C9GWS6	Hat1_N domain-containing protein. (418 aa)
	A0A4Y0ANM4	ULP_PROTEASE domain-containing protein. (709 aa)
	A0A4Y0AS55	Protein kinase domain-containing protein. (645 aa)
	A0A4Y0AV06	BRCT domain-containing protein. (1575 aa)
	A0A4Y0B5Z4	Uncharacterized protein. (116 aa)
	A0A4Y0BE15	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
	A0A4Y0BE35	Uncharacterized protein. (260 aa)
	A0A4Y0BEZ6	CCHC NOA-type domain-containing protein. (546 aa)
	A0A4Y0BFV2	Uncharacterized protein. (120 aa)
	A0A4Y0BG19	G_PROTEIN_RECEP_F3_4 domain-containing protein. (771 aa)
	A0A4Y0BGK0	LysM domain-containing protein. (1158 aa)
	A0A4Y0BHQ3	Protein kinase domain-containing protein. (1177 aa)
	A0A4Y0BI06	ZnMc domain-containing protein. (476 aa)
	A0A4Y0BI69	TLDc domain-containing protein. (280 aa)
	A0A4Y0BI87	Uncharacterized protein. (129 aa)
	A0A4Y0BII6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (800 aa)
	A0A4Y0BIZ3	TLDc domain-containing protein. (212 aa)
	A0A4Y0BJ16	Uncharacterized protein. (1469 aa)
	A0A182R6Q1	Akirin. (203 aa)
	A0A182R6S6	ULP_PROTEASE domain-containing protein. (864 aa)
	A0A182R8H1	DSPc domain-containing protein. (274 aa)
	A0A4Y0BPZ2	Protein kinase domain-containing protein. (2392 aa)
	A0A182R914	Uncharacterized protein; Belongs to the peptidase M16 family. (1065 aa)
	A0A182R9F3	Uncharacterized protein. (1141 aa)
	A0A182RAP6	Uncharacterized protein. (1748 aa)
	A0A182RC14	Uncharacterized protein. (127 aa)
	A0A182RCL2	Spaetzle domain-containing protein. (399 aa)
	A0A182RD75	SUMO-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
	A0A182RDR4	Uncharacterized protein. (742 aa)
	A0A182R9G8	Uncharacterized protein. (217 aa)
	A0A182R9G9	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (588 aa)
	A0A4Y0BS27	BTB domain-containing protein. (531 aa)
	A0A4Y0BS22	Uncharacterized protein. (939 aa)
	A0A4Y0BS18	Uncharacterized protein. (574 aa)
	A0A4Y0BRI1	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (388 aa)
	A0A4Y0BQI4	Uncharacterized protein. (117 aa)
	A0A4Y0BQ50	Ku domain-containing protein. (728 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R241	A0A182R6S6	Small ubiquitin-related modifier.	ULP_PROTEASE domain-containing protein.	0.908
A0A182R241	A0A182RD75	Small ubiquitin-related modifier.	SUMO-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.954
A0A182R241	A0A182RDR4	Small ubiquitin-related modifier.	Uncharacterized protein.	0.427
A0A182R241	A0A182RGF4	Small ubiquitin-related modifier.	RHD domain-containing protein.	0.671
A0A182R241	A0A182RIX6	Small ubiquitin-related modifier.	Poly [ADP-ribose] polymerase.	0.700
A0A182R241	A0A182RK53	Small ubiquitin-related modifier.	SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family.	0.958
A0A182R241	A0A182RT42	Small ubiquitin-related modifier.	ThiF domain-containing protein.	0.966
A0A182R241	A0A182RUV4	Small ubiquitin-related modifier.	Uncharacterized protein.	0.954
A0A182R241	A0A182RW08	Small ubiquitin-related modifier.	RING-type domain-containing protein.	0.463
A0A182R241	A0A182RYX1	Small ubiquitin-related modifier.	Aquaporin; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.908
A0A182R241	A0A182RZM0	Small ubiquitin-related modifier.	Uncharacterized protein.	0.747
A0A182R241	A0A182RZR2	Small ubiquitin-related modifier.	CCHC NOA-type domain-containing protein.	0.483
A0A182R241	A0A182S069	Small ubiquitin-related modifier.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.954
A0A182R241	A0A4Y0ANM4	Small ubiquitin-related modifier.	ULP_PROTEASE domain-containing protein.	0.908
A0A182R241	A0A4Y0AV06	Small ubiquitin-related modifier.	BRCT domain-containing protein.	0.795
A0A182R241	A0A4Y0BE15	Small ubiquitin-related modifier.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.954
A0A182R241	A0A4Y0BEZ6	Small ubiquitin-related modifier.	CCHC NOA-type domain-containing protein.	0.495
A0A182R241	A0A4Y0BII6	Small ubiquitin-related modifier.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.555
A0A182R241	A0A4Y0BJF1	Small ubiquitin-related modifier.	BTB domain-containing protein.	0.417
A0A182R241	A0A4Y0BJF7	Small ubiquitin-related modifier.	Uncharacterized protein.	0.417