(44 nodes) Protein polymerization network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182RVM1	WD_REPEATS_REGION domain-containing protein. (707 aa)
	A0A4Y0BFT8	Uncharacterized protein. (250 aa)
	A0A4Y0BGY8	Uncharacterized protein. (1222 aa)
	A0A4Y0BHB0	Uncharacterized protein. (393 aa)
	A0A4Y0BHN0	Uncharacterized protein. (115 aa)
	A0A4Y0BIP6	Uncharacterized protein. (1187 aa)
	A0A4Y0BJD2	Uncharacterized protein. (1435 aa)
	A0A4Y0BJW5	Uncharacterized protein. (575 aa)
	A0A4Y0BK25	Uncharacterized protein. (1222 aa)
	A0A4Y0BLN8	PACT_coil_coil domain-containing protein. (3312 aa)
	A0A4Y0BLS7	TPR_REGION domain-containing protein. (416 aa)
	A0A4Y0BMH2	Uncharacterized protein. (393 aa)
	A0A4Y0BN53	Calponin-homology (CH) domain-containing protein. (2192 aa)
	A0A4Y0BNW3	Uncharacterized protein. (1369 aa)
	A0A4Y0BPE6	BRO1 domain-containing protein. (850 aa)
	A0A4Y0BPP5	Gamma-tubulin complex component. (897 aa)
	A0A4Y0BQM9	Gelsolin-like domain-containing protein. (201 aa)
	A0A4Y0BQS4	PACT_coil_coil domain-containing protein. (1401 aa)
	A0A4Y0BQZ6	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. (242 aa)
	A0A4Y0BVE0	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. (147 aa)
	A0A4Y0BW35	Uncharacterized protein. (739 aa)
	A0A182RUX2	Uncharacterized protein. (163 aa)
	A0A182RTD3	Uncharacterized protein. (2113 aa)
	A0A182RT64	Uncharacterized protein. (101 aa)
	A0A182RST5	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (148 aa)
	A0A182RHF1	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	A0A182RGP4	Uncharacterized protein. (1121 aa)
	A0A182REK4	CAP-Gly domain-containing protein. (519 aa)
	A0A182RDF1	Uncharacterized protein. (111 aa)
	A0A182RCJ1	Uncharacterized protein. (497 aa)
	A0A182R9U0	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (657 aa)
	A0A182R499	Gamma-tubulin complex component. (567 aa)
	A0A182R476	Uncharacterized protein. (575 aa)
	A0A182R3B8	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (461 aa)
	A0A182R344	Uncharacterized protein. (1184 aa)
	A0A182R2X0	Uncharacterized protein. (1573 aa)
	A0A182R1I9	Tcp10_C domain-containing protein. (1051 aa)
	A0A182RSD0	Gamma-tubulin complex component. (1043 aa)
	A0A182RRT8	Uncharacterized protein. (76 aa)
	A0A182RRT7	Gamma-tubulin complex component. (853 aa)
	A0A182RR86	NUDE_C domain-containing protein. (512 aa)
	A0A182RME7	Uncharacterized protein. (429 aa)
	A0A182RJL9	Uncharacterized protein. (212 aa)
	A0A182RIZ2	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (304 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R1I9	A0A182R3B8	Tcp10_C domain-containing protein.	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	0.882
A0A182R1I9	A0A182R476	Tcp10_C domain-containing protein.	Uncharacterized protein.	0.851
A0A182R1I9	A0A182RR86	Tcp10_C domain-containing protein.	NUDE_C domain-containing protein.	0.494
A0A182R1I9	A0A182RSD0	Tcp10_C domain-containing protein.	Gamma-tubulin complex component.	0.409
A0A182R1I9	A0A182RTD3	Tcp10_C domain-containing protein.	Uncharacterized protein.	0.510
A0A182R1I9	A0A4Y0BJW5	Tcp10_C domain-containing protein.	Uncharacterized protein.	0.851
A0A182R1I9	A0A4Y0BLN8	Tcp10_C domain-containing protein.	PACT_coil_coil domain-containing protein.	0.747
A0A182R1I9	A0A4Y0BN53	Tcp10_C domain-containing protein.	Calponin-homology (CH) domain-containing protein.	0.628
A0A182R1I9	A0A4Y0BQS4	Tcp10_C domain-containing protein.	PACT_coil_coil domain-containing protein.	0.747
A0A182R2X0	A0A182R3B8	Uncharacterized protein.	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	0.959
A0A182R2X0	A0A182R499	Uncharacterized protein.	Gamma-tubulin complex component.	0.963
A0A182R2X0	A0A182RRT7	Uncharacterized protein.	Gamma-tubulin complex component.	0.955
A0A182R2X0	A0A182RRT8	Uncharacterized protein.	Uncharacterized protein.	0.947
A0A182R2X0	A0A182RSD0	Uncharacterized protein.	Gamma-tubulin complex component.	0.964
A0A182R2X0	A0A182RTD3	Uncharacterized protein.	Uncharacterized protein.	0.607
A0A182R2X0	A0A182RVM1	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.838
A0A182R2X0	A0A4Y0BFT8	Uncharacterized protein.	Uncharacterized protein.	0.576
A0A182R2X0	A0A4Y0BLN8	Uncharacterized protein.	PACT_coil_coil domain-containing protein.	0.419
A0A182R2X0	A0A4Y0BPP5	Uncharacterized protein.	Gamma-tubulin complex component.	0.576
A0A182R2X0	A0A4Y0BQS4	Uncharacterized protein.	PACT_coil_coil domain-containing protein.	0.419