(34 nodes) Positive regulation of filopodium assembly network (Anopheles funestus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	A0A182R3L5	W2 domain-containing protein. (417 aa)
	A0A182R1G8	Protein kinase domain-containing protein. (1128 aa)
	A0A182R7H8	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1287 aa)
	A0A182RCA2	WH2 domain-containing protein. (642 aa)
	A0A182RDS9	Uncharacterized protein. (2396 aa)
	A0A182RHF1	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	A0A182RIU8	Uncharacterized protein. (314 aa)
	A0A182RNP9	Uncharacterized protein. (202 aa)
	A0A182RPI9	SH3 domain-containing protein. (443 aa)
	A0A182RQX4	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (289 aa)
	A0A182RSJ6	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (374 aa)
	A0A182RTI1	Uncharacterized protein. (1154 aa)
	A0A182RTN0	Uncharacterized protein; Belongs to the actin family. (418 aa)
	A0A4Y0B5A0	Uncharacterized protein. (1157 aa)
	A0A4Y0B7K2	Uncharacterized protein. (1091 aa)
	A0A4Y0BD37	Uncharacterized protein. (75 aa)
	A0A4Y0BFY0	Uncharacterized protein. (1279 aa)
	A0A4Y0BGC2	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
	A0A4Y0BHA7	Uncharacterized protein. (1950 aa)
	A0A4Y0BHJ1	Uncharacterized protein. (1161 aa)
	A0A4Y0BI09	Uncharacterized protein. (7433 aa)
	A0A4Y0BI89	Uncharacterized protein. (1194 aa)
	A0A4Y0BJ40	Uncharacterized protein. (2026 aa)
	A0A4Y0BJE4	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (814 aa)
	A0A4Y0BJW0	Uncharacterized protein. (8410 aa)
	A0A4Y0BKN7	VASP_tetra domain-containing protein. (402 aa)
	A0A4Y0BL82	Uncharacterized protein. (7397 aa)
	A0A4Y0BLJ0	Uncharacterized protein. (1978 aa)
	A0A4Y0BLV0	Uncharacterized protein. (107 aa)
	A0A4Y0BN31	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
	A0A4Y0BPK3	WH1 domain-containing protein. (679 aa)
	A0A4Y0BQB5	Uncharacterized protein. (8719 aa)
	A0A4Y0BQJ5	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (485 aa)
	A0A4Y0BQQ2	Uncharacterized protein. (1921 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R1G8	A0A4Y0BGC2	Protein kinase domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.472
A0A182R1G8	A0A4Y0BJE4	Protein kinase domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.472
A0A182R1G8	A0A4Y0BN31	Protein kinase domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.472
A0A182R7H8	A0A182RCA2	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	WH2 domain-containing protein.	0.991
A0A182R7H8	A0A182RHF1	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.521
A0A182R7H8	A0A182RPI9	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	SH3 domain-containing protein.	0.993
A0A182R7H8	A0A182RSJ6	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.795
A0A182R7H8	A0A182RTN0	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Uncharacterized protein; Belongs to the actin family.	0.870
A0A182R7H8	A0A4Y0BD37	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Uncharacterized protein.	0.995
A0A182R7H8	A0A4Y0BGC2	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.425
A0A182R7H8	A0A4Y0BJE4	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.425
A0A182R7H8	A0A4Y0BN31	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.425
A0A182RCA2	A0A182R7H8	WH2 domain-containing protein.	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	0.991
A0A182RCA2	A0A182RHF1	WH2 domain-containing protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.509
A0A182RCA2	A0A182RPI9	WH2 domain-containing protein.	SH3 domain-containing protein.	0.993
A0A182RCA2	A0A182RSJ6	WH2 domain-containing protein.	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.797
A0A182RCA2	A0A182RTN0	WH2 domain-containing protein.	Uncharacterized protein; Belongs to the actin family.	0.819
A0A182RCA2	A0A4Y0BD37	WH2 domain-containing protein.	Uncharacterized protein.	0.994
A0A182RCA2	A0A4Y0BKN7	WH2 domain-containing protein.	VASP_tetra domain-containing protein.	0.458
A0A182RCA2	A0A4Y0BPK3	WH2 domain-containing protein.	WH1 domain-containing protein.	0.458