(51 nodes) Monovalent inorganic cation homeostasis network (Anopheles funestus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

gene neighborhood

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Your Input:
	A0A4Y0BGJ8	Uncharacterized protein. (308 aa)
	A0A182RDX4	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (347 aa)
	A0A182RDF8	AA_permease domain-containing protein. (704 aa)
	A0A182RC44	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (601 aa)
	A0A182RBU0	Vacuolar H+ ATPase AC45 accessory subunit. (389 aa)
	A0A182RAC2	Uncharacterized protein. (934 aa)
	A0A182R8D8	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (864 aa)
	A0A182R8A5	Uncharacterized protein. (1119 aa)
	A0A182R6C7	Ammonium_transp domain-containing protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (471 aa)
	A0A182R614	Uncharacterized protein. (391 aa)
	A0A4Y0ALR8	Anion exchange protein. (1210 aa)
	A0A182R4U3	Uncharacterized protein. (1136 aa)
	A0A4Y0AQ60	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (852 aa)
	A0A4Y0AW75	Anion exchange protein. (1245 aa)
	A0A4Y0AWB9	Anion exchange protein. (1166 aa)
	A0A4Y0AYU5	Anion exchange protein. (1286 aa)
	A0A4Y0B268	Sodium/potassium-transporting ATPase subunit alpha. (1000 aa)
	A0A4Y0B284	Sodium/potassium-transporting ATPase subunit alpha. (1000 aa)
	A0A4Y0B2M5	Sodium/potassium-transporting ATPase subunit alpha. (1000 aa)
	A0A4Y0B4W7	Sodium/potassium-transporting ATPase subunit alpha. (1000 aa)
	A0A4Y0BEL1	WASH_WAHD domain-containing protein. (471 aa)
	A0A4Y0BEQ1	ATP-synt_ab domain-containing protein. (183 aa)
	A0A4Y0BGS9	Uncharacterized protein. (320 aa)
	A0A4Y0BI65	Uncharacterized protein. (310 aa)
	A0A4Y0BK63	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (1213 aa)
	A0A4Y0BLN0	Uncharacterized protein. (1473 aa)
	A0A4Y0BNX3	Uncharacterized protein. (963 aa)
	A0A4Y0BP05	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (1129 aa)
	A0A4Y0BPB2	Uncharacterized protein. (1058 aa)
	A0A4Y0BRQ1	Uncharacterized protein. (452 aa)
	A0A182R405	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (666 aa)
	A0A182R3S6	Anion exchange protein. (1214 aa)
	A0A182R3G5	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (348 aa)
	A0A182R2W3	Uncharacterized protein. (685 aa)
	A0A182REL4	WASH_WAHD domain-containing protein. (471 aa)
	A0A182RFJ1	Uncharacterized protein. (594 aa)
	A0A182RFY6	WD_REPEATS_REGION domain-containing protein. (806 aa)
	A0A182RGA3	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (688 aa)
	A0A182RGS5	Anion exchange protein. (1381 aa)
	A0A182RIV1	WD_REPEATS_REGION domain-containing protein. (3507 aa)
	A0A182RN01	Chloride channel protein. (904 aa)
	A0A182RQ21	Sodium/potassium-transporting ATPase subunit alpha. (1034 aa)
	A0A182RQ39	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (498 aa)
	A0A182RRH8	Uncharacterized protein. (250 aa)
	A0A182RWF1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (586 aa)
	A0A182RY66	Battenin. (445 aa)
	A0A1I8JU73	Electroneutral potassium-chloride cotransporter. (1085 aa)
	A0A1I8JUR3	Ammonium transporter. (583 aa)
	A0A453YNN5	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
	A0A453YNR9	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (806 aa)
	A0A4Y0ALC9	Anion exchange protein. (1199 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R3G5	A0A182R614	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	Uncharacterized protein.	0.961
A0A182R3G5	A0A182R8A5	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	Uncharacterized protein.	0.974
A0A182R3G5	A0A182R8D8	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.996
A0A182R3G5	A0A182RBU0	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	Vacuolar H+ ATPase AC45 accessory subunit.	0.996
A0A182R3G5	A0A182RDX4	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.935
A0A182R3G5	A0A182RFY6	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	WD_REPEATS_REGION domain-containing protein.	0.593
A0A182R3G5	A0A182RQ21	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	Sodium/potassium-transporting ATPase subunit alpha.	0.435
A0A182R3G5	A0A182RQ39	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.995
A0A182R3G5	A0A453YNN5	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.995
A0A182R3G5	A0A453YNR9	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.996
A0A182R3G5	A0A4Y0AQ60	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.997
A0A182R3G5	A0A4Y0B268	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	Sodium/potassium-transporting ATPase subunit alpha.	0.435
A0A182R3G5	A0A4Y0B284	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	Sodium/potassium-transporting ATPase subunit alpha.	0.435
A0A182R3G5	A0A4Y0B2M5	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	Sodium/potassium-transporting ATPase subunit alpha.	0.435
A0A182R3G5	A0A4Y0B4W7	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	Sodium/potassium-transporting ATPase subunit alpha.	0.435
A0A182R3G5	A0A4Y0BEQ1	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	ATP-synt_ab domain-containing protein.	0.993
A0A182R3S6	A0A182R6C7	Anion exchange protein.	Ammonium_transp domain-containing protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.	0.416
A0A182R405	A0A182RGS5	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.	Anion exchange protein.	0.567
A0A182R405	A0A182RN01	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.	Chloride channel protein.	0.434
A0A182R405	A0A1I8JUR3	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.	Ammonium transporter.	0.458