(50 nodes) Regulation of microtubule cytoskeleton organization network (Anopheles funestus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182RW25	Spectrin beta chain; Belongs to the spectrin family. (2361 aa)
	A0A4Y0BLN3	Uncharacterized protein. (1595 aa)
	A0A4Y0BL82	Uncharacterized protein. (7397 aa)
	A0A4Y0BL02	Uncharacterized protein. (269 aa)
	A0A4Y0BJW0	Uncharacterized protein. (8410 aa)
	A0A4Y0BIY7	Uncharacterized protein. (923 aa)
	A0A4Y0BI19	GB1/RHD3-type G domain-containing protein. (539 aa)
	A0A4Y0BI09	Uncharacterized protein. (7433 aa)
	A0A4Y0BG99	TFCD_C domain-containing protein. (1166 aa)
	A0A4Y0B274	Uncharacterized protein. (248 aa)
	A0A4Y0B113	Uncharacterized protein. (250 aa)
	A0A4Y0AVW7	Alpha-tubulin N-acetyltransferase; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynam [...] (276 aa)
	A0A453YNN0	Cnn_1N domain-containing protein. (1214 aa)
	A0A453YNJ9	Cnn_1N domain-containing protein. (1217 aa)
	A0A182S590	Uncharacterized protein. (360 aa)
	A0A182RXV6	Uncharacterized protein; Belongs to the intermediate filament family. (567 aa)
	A0A182RM85	Uncharacterized protein. (2809 aa)
	A0A182RNJ1	Uncharacterized protein. (256 aa)
	A0A182RPC2	TPR_MLP1_2 domain-containing protein. (2752 aa)
	A0A182RPZ9	Uncharacterized protein. (680 aa)
	A0A182R1T8	Uncharacterized protein. (269 aa)
	A0A182R5A4	Uncharacterized protein. (261 aa)
	A0A182R5N6	Uncharacterized protein. (258 aa)
	A0A182RW55	Ubiquitin-like domain-containing protein. (504 aa)
	A0A182RU68	AAA domain-containing protein; Belongs to the AAA ATPase family. (622 aa)
	A0A182RTD3	Uncharacterized protein. (2113 aa)
	A0A182RSG5	Uncharacterized protein. (4795 aa)
	A0A182RRB8	Uncharacterized protein. (299 aa)
	A0A182R6U7	Uncharacterized protein. (801 aa)
	A0A182R969	SCA7 domain-containing protein. (1277 aa)
	A0A182RDF1	Uncharacterized protein. (111 aa)
	A0A182RER3	Uncharacterized protein. (1954 aa)
	A0A182RFH4	Alpha-tubulin N-acetyltransferase; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynam [...] (524 aa)
	A0A182RGX5	VHL domain-containing protein. (151 aa)
	A0A182RH46	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (765 aa)
	A0A182RJL9	Uncharacterized protein. (212 aa)
	A0A182RKF2	Uncharacterized protein. (220 aa)
	A0A182RKJ7	Uncharacterized protein. (364 aa)
	A0A182RL54	Uncharacterized protein. (207 aa)
	A0A4Y0BWH5	Uncharacterized protein. (966 aa)
	A0A4Y0BW98	TFCD_C domain-containing protein. (577 aa)
	A0A4Y0BSF2	Spastin; ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation; Belongs to the AAA ATPase family. Spastin subfamily. (906 aa)
	A0A4Y0BQB5	Uncharacterized protein. (8719 aa)
	A0A4Y0BPJ1	Uncharacterized protein. (174 aa)
	A0A4Y0BN29	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (870 aa)
	A0A4Y0BN22	Uncharacterized protein. (293 aa)
	A0A4Y0BN09	N-acetyltransferase domain-containing protein. (203 aa)
	A0A4Y0BMY5	Uncharacterized protein. (794 aa)
	A0A4Y0BMB3	Uncharacterized protein. (2417 aa)
	A0A4Y0BLU2	Uncharacterized protein. (1712 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R1T8	A0A182RL54	Uncharacterized protein.	Uncharacterized protein.	0.703
A0A182R5A4	A0A182RER3	Uncharacterized protein.	Uncharacterized protein.	0.673
A0A182R5A4	A0A182RH46	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.882
A0A182R5A4	A0A182RL54	Uncharacterized protein.	Uncharacterized protein.	0.912
A0A182R5A4	A0A182RSG5	Uncharacterized protein.	Uncharacterized protein.	0.430
A0A182R5A4	A0A182RTD3	Uncharacterized protein.	Uncharacterized protein.	0.941
A0A182R5A4	A0A182RXV6	Uncharacterized protein.	Uncharacterized protein; Belongs to the intermediate filament family.	0.487
A0A182R5A4	A0A453YNJ9	Uncharacterized protein.	Cnn_1N domain-containing protein.	0.405
A0A182R5A4	A0A453YNN0	Uncharacterized protein.	Cnn_1N domain-containing protein.	0.405
A0A182R5A4	A0A4Y0BG99	Uncharacterized protein.	TFCD_C domain-containing protein.	0.454
A0A182R5A4	A0A4Y0BI09	Uncharacterized protein.	Uncharacterized protein.	0.663
A0A182R5A4	A0A4Y0BIY7	Uncharacterized protein.	Uncharacterized protein.	0.441
A0A182R5A4	A0A4Y0BJW0	Uncharacterized protein.	Uncharacterized protein.	0.663
A0A182R5A4	A0A4Y0BL82	Uncharacterized protein.	Uncharacterized protein.	0.663
A0A182R5A4	A0A4Y0BLU2	Uncharacterized protein.	Uncharacterized protein.	0.418
A0A182R5A4	A0A4Y0BQB5	Uncharacterized protein.	Uncharacterized protein.	0.663
A0A182R5A4	A0A4Y0BW98	Uncharacterized protein.	TFCD_C domain-containing protein.	0.454
A0A182R5N6	A0A4Y0BWH5	Uncharacterized protein.	Uncharacterized protein.	0.424
A0A182R6U7	A0A182RXV6	Uncharacterized protein.	Uncharacterized protein; Belongs to the intermediate filament family.	0.478
A0A182R969	A0A4Y0BI09	SCA7 domain-containing protein.	Uncharacterized protein.	0.734