(11 nodes) Phosphorylation of RNA polymerase II C-terminal domain network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4Y0BGE2	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (148 aa)
	A0A4Y0BTY4	Uncharacterized protein. (288 aa)
	A0A182R2E6	CYCLIN domain-containing protein; Belongs to the cyclin family. (1482 aa)
	A0A182R6M8	Uncharacterized protein. (638 aa)
	A0A182RG34	Uncharacterized protein; Belongs to the cyclin family. (333 aa)
	A0A182RKF3	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (497 aa)
	A0A182RQJ4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (342 aa)
	A0A182RWC7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (397 aa)
	A0A182RXE6	Protein kinase domain-containing protein. (1488 aa)
	A0A4Y0BGA4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (278 aa)
	A0A4Y0BLY5	Uncharacterized protein. (73 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R2E6	A0A182RG34	CYCLIN domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein; Belongs to the cyclin family.	0.812
A0A182R2E6	A0A182RQJ4	CYCLIN domain-containing protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.755
A0A182R2E6	A0A182RWC7	CYCLIN domain-containing protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.996
A0A182R2E6	A0A182RXE6	CYCLIN domain-containing protein; Belongs to the cyclin family.	Protein kinase domain-containing protein.	0.975
A0A182R2E6	A0A4Y0BTY4	CYCLIN domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.582
A0A182R6M8	A0A182RG34	Uncharacterized protein.	Uncharacterized protein; Belongs to the cyclin family.	0.997
A0A182R6M8	A0A182RKF3	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.972
A0A182R6M8	A0A182RQJ4	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.970
A0A182R6M8	A0A182RWC7	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.411
A0A182R6M8	A0A4Y0BGA4	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.972
A0A182R6M8	A0A4Y0BGE2	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.972
A0A182R6M8	A0A4Y0BLY5	Uncharacterized protein.	Uncharacterized protein.	0.991
A0A182R6M8	A0A4Y0BTY4	Uncharacterized protein.	Uncharacterized protein.	0.999
A0A182RG34	A0A182R2E6	Uncharacterized protein; Belongs to the cyclin family.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.812
A0A182RG34	A0A182R6M8	Uncharacterized protein; Belongs to the cyclin family.	Uncharacterized protein.	0.997
A0A182RG34	A0A182RKF3	Uncharacterized protein; Belongs to the cyclin family.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.955
A0A182RG34	A0A182RQJ4	Uncharacterized protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.989
A0A182RG34	A0A182RWC7	Uncharacterized protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.716
A0A182RG34	A0A182RXE6	Uncharacterized protein; Belongs to the cyclin family.	Protein kinase domain-containing protein.	0.907
A0A182RG34	A0A4Y0BGA4	Uncharacterized protein; Belongs to the cyclin family.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.955