45 items (Anopheles funestus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4Y0AQ35	Uncharacterized protein. (812 aa)
	A0A182RZQ7	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1178 aa)
	A0A182RYA4	UmuC domain-containing protein. (746 aa)
	A0A182RY47	DBF4-type domain-containing protein. (3248 aa)
	A0A182RXT7	Uncharacterized protein. (569 aa)
	A0A182RWY3	Uncharacterized protein. (590 aa)
	A0A182RVZ3	Uncharacterized protein. (591 aa)
	A0A182RU78	DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1353 aa)
	A0A182RT41	RNase H domain-containing protein. (362 aa)
	A0A182RSW7	CYCLIN domain-containing protein; Belongs to the cyclin family. (554 aa)
	A0A182RRS7	Zinc-hook domain-containing protein. (1308 aa)
	A0A182RR40	Uncharacterized protein. (1049 aa)
	A0A182RPL3	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
	A0A182RPG8	Uncharacterized protein. (186 aa)
	A0A182RNG5	UmuC domain-containing protein. (710 aa)
	A0A182RNF2	Uncharacterized protein. (1979 aa)
	A0A182RNA9	Uncharacterized protein. (1459 aa)
	A0A182RIX4	WD_REPEATS_REGION domain-containing protein. (429 aa)
	A0A182RHU9	Uncharacterized protein; Belongs to the ATP-dependent DNA ligase family. (921 aa)
	A0A182RHU0	Uncharacterized protein. (718 aa)
	A0A182RFZ2	ApaG domain-containing protein. (401 aa)
	A0A182RF05	Uncharacterized protein. (1628 aa)
	A0A182REB2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (521 aa)
	A0A182REB1	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2225 aa)
	A0A182RE54	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (880 aa)
	A0A182RDN7	Uncharacterized protein. (465 aa)
	A0A182RDC6	Uncharacterized protein. (122 aa)
	A0A182RD86	DNA polymerase. (1552 aa)
	A0A182RCR4	Uncharacterized protein. (727 aa)
	A0A182RCN6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (646 aa)
	A0A182RCK2	Uncharacterized protein. (2053 aa)
	A0A182RA20	CDT1 domain-containing protein. (747 aa)
	A0A182R8Y7	CRC domain-containing protein. (750 aa)
	A0A4Y0BKG0	Uncharacterized protein. (2242 aa)
	A0A182R8B9	Uncharacterized protein. (891 aa)
	A0A182R6W2	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	A0A182R806	Uncharacterized protein. (214 aa)
	A0A182R4Q9	CULLIN_2 domain-containing protein; Belongs to the cullin family. (756 aa)
	A0A182R4E9	DNA_pol_B domain-containing protein. (184 aa)
	A0A182R433	Uncharacterized protein. (785 aa)
	A0A182R366	CPSF_A domain-containing protein. (1138 aa)
	A0A4Y0BSP6	Uncharacterized protein. (138 aa)
	A0A4Y0BU02	POLAc domain-containing protein. (1142 aa)
	A0A4Y0BH52	Uncharacterized protein. (718 aa)
	A0A4Y0BGA9	DNA polymerase. (1092 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R366	A0A182R433	CPSF_A domain-containing protein.	Uncharacterized protein.	0.691
A0A182R366	A0A182R4E9	CPSF_A domain-containing protein.	DNA_pol_B domain-containing protein.	0.724
A0A182R366	A0A182R4Q9	CPSF_A domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.999
A0A182R366	A0A182R6W2	CPSF_A domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.824
A0A182R366	A0A182RA20	CPSF_A domain-containing protein.	CDT1 domain-containing protein.	0.829
A0A182R366	A0A182RD86	CPSF_A domain-containing protein.	DNA polymerase.	0.681
A0A182R366	A0A182REB1	CPSF_A domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.902
A0A182R366	A0A182REB2	CPSF_A domain-containing protein.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.780
A0A182R366	A0A182RF05	CPSF_A domain-containing protein.	Uncharacterized protein.	0.513
A0A182R366	A0A182RHU9	CPSF_A domain-containing protein.	Uncharacterized protein; Belongs to the ATP-dependent DNA ligase family.	0.657
A0A182R366	A0A182RIX4	CPSF_A domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.959
A0A182R366	A0A182RNA9	CPSF_A domain-containing protein.	Uncharacterized protein.	0.487
A0A182R366	A0A182RNG5	CPSF_A domain-containing protein.	UmuC domain-containing protein.	0.481
A0A182R366	A0A182RPL3	CPSF_A domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.669
A0A182R366	A0A182RYA4	CPSF_A domain-containing protein.	UmuC domain-containing protein.	0.466
A0A182R366	A0A182RZQ7	CPSF_A domain-containing protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.481
A0A182R366	A0A4Y0BGA9	CPSF_A domain-containing protein.	DNA polymerase.	0.724
A0A182R366	A0A4Y0BKG0	CPSF_A domain-containing protein.	Uncharacterized protein.	0.681
A0A182R433	A0A182R366	Uncharacterized protein.	CPSF_A domain-containing protein.	0.691
A0A182R433	A0A182R4E9	Uncharacterized protein.	DNA_pol_B domain-containing protein.	0.546