(51 nodes) Malpighian tubule development network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182RAU9	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
	A0A4Y0BNS1	Uncharacterized protein. (858 aa)
	A0A4Y0BN04	Uncharacterized protein. (745 aa)
	A0A4Y0BMK3	Uncharacterized protein. (884 aa)
	A0A4Y0BLS3	Uncharacterized protein. (192 aa)
	A0A4Y0BLN7	BHLH domain-containing protein. (562 aa)
	A0A4Y0BLM4	Uncharacterized protein. (776 aa)
	A0A4Y0BLL2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (428 aa)
	A0A4Y0BLD0	Uncharacterized protein. (613 aa)
	A0A4Y0BKM4	Uncharacterized protein. (2291 aa)
	A0A4Y0BKH6	Uncharacterized protein; Belongs to the chordin family. (991 aa)
	A0A4Y0BK22	Uncharacterized protein. (2820 aa)
	A0A4Y0BJD4	Uncharacterized protein. (605 aa)
	A0A4Y0BJ92	Fork-head domain-containing protein. (472 aa)
	A0A4Y0BIB4	Uncharacterized protein. (1176 aa)
	A0A4Y0BIA6	Uncharacterized protein. (519 aa)
	A0A4Y0BHF6	Uncharacterized protein. (1494 aa)
	A0A4Y0BGN0	Homeobox protein cut-like. (2097 aa)
	A0A4Y0BG23	Homeobox domain-containing protein. (454 aa)
	A0A4Y0B206	Receptor protein-tyrosine kinase. (1488 aa)
	A0A4Y0AVE2	Uncharacterized protein. (2920 aa)
	A0A3F2YXP8	Uncharacterized protein. (2757 aa)
	A0A182RYW2	Uncharacterized protein. (774 aa)
	A0A182RYV3	BHLH domain-containing protein. (364 aa)
	A0A182RVJ1	Uncharacterized protein. (843 aa)
	A0A182RVG7	Uncharacterized protein. (640 aa)
	A0A182RSL2	ETF domain-containing protein. (332 aa)
	A0A182RPP5	Receptor protein-tyrosine kinase. (1465 aa)
	A0A182RPD0	Uncharacterized protein. (1637 aa)
	A0A182RMB5	Protein kinase domain-containing protein. (90 aa)
	A0A182RM68	SPARC_Ca_bdg domain-containing protein. (327 aa)
	A0A182RH81	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
	A0A182RGA6	Rhomboid domain-containing protein. (389 aa)
	A0A182RFP6	Uncharacterized protein. (2972 aa)
	A0A182RFE8	Uncharacterized protein. (867 aa)
	A0A182RES1	Uncharacterized protein. (620 aa)
	A0A182RE98	Uncharacterized protein. (661 aa)
	A0A182RCX3	Uncharacterized protein. (1940 aa)
	A0A182R8K6	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (736 aa)
	A0A182R7R6	PID domain-containing protein. (573 aa)
	A0A182R5P1	Uncharacterized protein; Belongs to the DOCK family. (1087 aa)
	A0A182R2J9	Receptor protein-tyrosine kinase. (1187 aa)
	A0A182R2A8	Uncharacterized protein. (716 aa)
	A0A182R287	Uncharacterized protein. (1380 aa)
	A0A182R260	Uncharacterized protein. (1822 aa)
	A0A182R1H5	Uncharacterized protein. (709 aa)
	A0A4Y0BT55	Collagen IV NC1 domain-containing protein. (1816 aa)
	A0A4Y0BSV4	Uncharacterized protein. (896 aa)
	A0A4Y0BRV6	Uncharacterized protein. (207 aa)
	A0A4Y0BRP9	ETS domain-containing protein. (579 aa)
	A0A4Y0BPZ0	Uncharacterized protein. (734 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R1H5	A0A182RFE8	Uncharacterized protein.	Uncharacterized protein.	0.999
A0A182R1H5	A0A4Y0BK22	Uncharacterized protein.	Uncharacterized protein.	0.426
A0A182R1H5	A0A4Y0BKM4	Uncharacterized protein.	Uncharacterized protein.	0.426
A0A182R260	A0A182R287	Uncharacterized protein.	Uncharacterized protein.	0.482
A0A182R260	A0A182R7R6	Uncharacterized protein.	PID domain-containing protein.	0.680
A0A182R260	A0A182RAU9	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.638
A0A182R260	A0A182RCX3	Uncharacterized protein.	Uncharacterized protein.	0.726
A0A182R260	A0A182RH81	Uncharacterized protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.457
A0A182R260	A0A4Y0BLS3	Uncharacterized protein.	Uncharacterized protein.	0.745
A0A182R260	A0A4Y0BNS1	Uncharacterized protein.	Uncharacterized protein.	0.658
A0A182R260	A0A4Y0BRV6	Uncharacterized protein.	Uncharacterized protein.	0.745
A0A182R260	A0A4Y0BSV4	Uncharacterized protein.	Uncharacterized protein.	0.658
A0A182R287	A0A182R260	Uncharacterized protein.	Uncharacterized protein.	0.482
A0A182R287	A0A182R8K6	Uncharacterized protein.	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.	0.561
A0A182R287	A0A4Y0BLS3	Uncharacterized protein.	Uncharacterized protein.	0.932
A0A182R287	A0A4Y0BRV6	Uncharacterized protein.	Uncharacterized protein.	0.932
A0A182R2J9	A0A182R5P1	Receptor protein-tyrosine kinase.	Uncharacterized protein; Belongs to the DOCK family.	0.626
A0A182R2J9	A0A182RPP5	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.844
A0A182R2J9	A0A4Y0B206	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.844
A0A182R2J9	A0A4Y0BLS3	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.545