(59 nodes) Regulation of plasma membrane bounded cell projection assembly network (Anopheles funestus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182RA01	Uncharacterized protein. (187 aa)
	A0A182RTN0	Uncharacterized protein; Belongs to the actin family. (418 aa)
	A0A182RYW1	Autophagy protein 5; Involved in autophagic vesicle formation. (265 aa)
	A0A182RZC5	Uncharacterized protein. (2962 aa)
	A0A1I8JUN5	Centrosomal protein CEP120. (901 aa)
	A0A3F2YXP8	Uncharacterized protein. (2757 aa)
	A0A4Y0B5A0	Uncharacterized protein. (1157 aa)
	A0A4Y0B7K2	Uncharacterized protein. (1091 aa)
	A0A4Y0BD37	Uncharacterized protein. (75 aa)
	A0A4Y0BFY0	Uncharacterized protein. (1279 aa)
	A0A4Y0BGC2	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
	A0A4Y0BHA7	Uncharacterized protein. (1950 aa)
	A0A4Y0BHD7	Uncharacterized protein. (656 aa)
	A0A4Y0BHJ1	Uncharacterized protein. (1161 aa)
	A0A4Y0BI09	Uncharacterized protein. (7433 aa)
	A0A4Y0BI89	Uncharacterized protein. (1194 aa)
	A0A4Y0BJ40	Uncharacterized protein. (2026 aa)
	A0A4Y0BJE4	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (814 aa)
	A0A4Y0BJW0	Uncharacterized protein. (8410 aa)
	A0A4Y0BJX4	Uncharacterized protein. (1758 aa)
	A0A4Y0BKN7	VASP_tetra domain-containing protein. (402 aa)
	A0A4Y0BKT7	Uncharacterized protein. (1703 aa)
	A0A4Y0BL82	Uncharacterized protein. (7397 aa)
	A0A4Y0BLJ0	Uncharacterized protein. (1978 aa)
	A0A4Y0BLS3	Uncharacterized protein. (192 aa)
	A0A4Y0BLV0	Uncharacterized protein. (107 aa)
	A0A4Y0BN31	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
	A0A4Y0BPH3	Uncharacterized protein. (2431 aa)
	A0A4Y0BPK3	WH1 domain-containing protein. (679 aa)
	A0A4Y0BQB5	Uncharacterized protein. (8719 aa)
	A0A4Y0BQJ5	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (485 aa)
	A0A4Y0BQQ2	Uncharacterized protein. (1921 aa)
	A0A4Y0BRF3	Uncharacterized protein. (384 aa)
	A0A4Y0BRV6	Uncharacterized protein. (207 aa)
	A0A4Y0BVG4	Uncharacterized protein. (678 aa)
	A0A182RIU8	Uncharacterized protein. (314 aa)
	A0A182RIM4	Uncharacterized protein. (726 aa)
	A0A182RHF1	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	A0A182RGP4	Uncharacterized protein. (1121 aa)
	A0A182RDS9	Uncharacterized protein. (2396 aa)
	A0A182RCP0	Uncharacterized protein. (342 aa)
	A0A182RCA2	WH2 domain-containing protein. (642 aa)
	A0A182RBT4	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (275 aa)
	A0A182RAN7	Uncharacterized protein. (246 aa)
	A0A182RTI1	Uncharacterized protein. (1154 aa)
	A0A182R8E3	Uncharacterized protein. (343 aa)
	A0A182R7V6	Uncharacterized protein. (1813 aa)
	A0A182R7S8	Uncharacterized protein. (958 aa)
	A0A182R7H8	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1287 aa)
	A0A182R3L5	W2 domain-containing protein. (417 aa)
	A0A182R260	Uncharacterized protein. (1822 aa)
	A0A182R211	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (490 aa)
	A0A182R1G8	Protein kinase domain-containing protein. (1128 aa)
	A0A182RST5	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (148 aa)
	A0A182RSJ6	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (374 aa)
	A0A182RQX4	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (289 aa)
	A0A182RPI9	SH3 domain-containing protein. (443 aa)
	A0A182RNP9	Uncharacterized protein. (202 aa)
	A0A182RM36	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (395 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R1G8	A0A182R7V6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.581
A0A182R1G8	A0A4Y0BGC2	Protein kinase domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.472
A0A182R1G8	A0A4Y0BJE4	Protein kinase domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.472
A0A182R1G8	A0A4Y0BKT7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.518
A0A182R1G8	A0A4Y0BLS3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.602
A0A182R1G8	A0A4Y0BN31	Protein kinase domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.472
A0A182R1G8	A0A4Y0BRV6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.602
A0A182R211	A0A182R7S8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.489
A0A182R211	A0A4Y0BI89	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.568
A0A182R211	A0A4Y0BJX4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.546
A0A182R211	A0A4Y0BLJ0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.568
A0A182R211	A0A4Y0BPH3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.546
A0A182R211	A0A4Y0BQQ2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.568
A0A182R260	A0A182RIU8	Uncharacterized protein.	Uncharacterized protein.	0.995
A0A182R260	A0A182RNP9	Uncharacterized protein.	Uncharacterized protein.	0.435
A0A182R260	A0A4Y0BGC2	Uncharacterized protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.958
A0A182R260	A0A4Y0BI89	Uncharacterized protein.	Uncharacterized protein.	0.726
A0A182R260	A0A4Y0BJE4	Uncharacterized protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.958
A0A182R260	A0A4Y0BLJ0	Uncharacterized protein.	Uncharacterized protein.	0.726
A0A182R260	A0A4Y0BLS3	Uncharacterized protein.	Uncharacterized protein.	0.745