(84 nodes) C2 domain superfamily network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4Y0BIG7	Uncharacterized protein; Belongs to the DOCK family. (2233 aa)
	A0A4Y0BIA2	Uncharacterized protein. (1289 aa)
	A0A4Y0BI29	Uncharacterized protein. (1165 aa)
	A0A4Y0BHZ3	Uncharacterized protein. (1968 aa)
	A0A4Y0BHR8	Uncharacterized protein. (542 aa)
	A0A4Y0BHE3	Uncharacterized protein. (1314 aa)
	A0A4Y0BH80	Uncharacterized protein. (2439 aa)
	A0A4Y0BGX9	Uncharacterized protein; Belongs to the DOCK family. (2096 aa)
	A0A4Y0BGX0	Uncharacterized protein. (1995 aa)
	A0A4Y0BGV5	E3 ubiquitin-protein ligase. (831 aa)
	A0A4Y0BFA3	Uncharacterized protein. (271 aa)
	A0A4Y0BF13	C2 domain-containing protein. (657 aa)
	A0A4Y0BCU9	Uncharacterized protein. (1482 aa)
	A0A4Y0B8T7	Uncharacterized protein. (1053 aa)
	A0A4Y0B7A3	Uncharacterized protein. (855 aa)
	A0A4Y0B2U4	Uncharacterized protein. (4256 aa)
	A0A4Y0AYI1	Uncharacterized protein. (1443 aa)
	A0A4Y0AXX4	E3 ubiquitin-protein ligase. (892 aa)
	A0A4Y0BUB3	Uncharacterized protein. (271 aa)
	A0A4Y0BS96	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1153 aa)
	A0A4Y0BRZ0	Uncharacterized protein. (598 aa)
	A0A182RHM1	Uncharacterized protein. (2099 aa)
	A0A182RHA1	C2 domain-containing protein. (1457 aa)
	A0A182RH59	Uncharacterized protein. (981 aa)
	A0A182RFQ2	Uncharacterized protein. (946 aa)
	A0A4Y0BPH3	Uncharacterized protein. (2431 aa)
	A0A182RBK5	Uncharacterized protein. (437 aa)
	A0A182RAE5	Phosphatidylinositol 3-kinase catalytic subunit type 3. (885 aa)
	A0A182R9S7	Uncharacterized protein. (981 aa)
	A0A182R8E2	Uncharacterized protein. (1289 aa)
	A0A182R795	J domain-containing protein. (782 aa)
	A0A182R6T0	Uncharacterized protein; Belongs to the DOCK family. (2078 aa)
	A0A182R6M6	Uncharacterized protein. (1485 aa)
	A0A182R5P9	Uncharacterized protein. (868 aa)
	A0A182R5P1	Uncharacterized protein; Belongs to the DOCK family. (1087 aa)
	A0A182R520	C2 domain-containing protein. (1071 aa)
	A0A182R468	Uncharacterized protein. (1334 aa)
	A0A182R390	Uncharacterized protein. (1187 aa)
	A0A182R219	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1171 aa)
	A0A182RJ28	Uncharacterized protein. (1111 aa)
	A0A182RJW0	Uncharacterized protein. (1576 aa)
	A0A182RK35	Uncharacterized protein. (510 aa)
	A0A182RN61	RPGR1_C domain-containing protein. (959 aa)
	A0A182RNZ1	Uncharacterized protein. (468 aa)
	A0A182RQC8	Uncharacterized protein. (4398 aa)
	A0A182RQY9	C2 domain-containing protein. (493 aa)
	A0A182RS41	Phosphoinositide phospholipase C. (2144 aa)
	A0A182RSB9	Uncharacterized protein. (2183 aa)
	A0A182RT13	Uncharacterized protein. (948 aa)
	A0A182RUL2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1978 aa)
	A0A182RV26	Uncharacterized protein. (1208 aa)
	A0A182RVT5	FIP-RBD domain-containing protein. (592 aa)
	A0A182RVU3	PH domain-containing protein. (1404 aa)
	A0A182RW64	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1218 aa)
	A0A182RW66	C2 domain-containing protein. (545 aa)
	A0A182RXM4	Uncharacterized protein. (1198 aa)
	A0A182RYD0	Uncharacterized protein. (995 aa)
	A0A182RZ16	Uncharacterized protein. (848 aa)
	A0A1I8JUN5	Centrosomal protein CEP120. (901 aa)
	A0A1Y9HE85	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (747 aa)
	A0A4Y0AMY1	Uncharacterized protein. (873 aa)
	A0A4Y0AW44	Uncharacterized protein. (760 aa)
	A0A4Y0BP04	C2 domain-containing protein. (342 aa)
	A0A4Y0BNZ6	Non-specific serine/threonine protein kinase. (544 aa)
	A0A4Y0BNW5	Uncharacterized protein. (2173 aa)
	A0A4Y0BNL3	Uncharacterized protein; Belongs to the DOCK family. (2033 aa)
	A0A4Y0BNK3	Uncharacterized protein. (1545 aa)
	A0A4Y0BMS8	Uncharacterized protein. (603 aa)
	A0A4Y0BLW5	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1429 aa)
	A0A4Y0BLU7	Uncharacterized protein. (1279 aa)
	A0A4Y0BLA7	Uncharacterized protein. (1719 aa)
	A0A4Y0BLA2	Uncharacterized protein. (1313 aa)
	A0A4Y0BL74	Uncharacterized protein. (1970 aa)
	A0A4Y0BKF1	Uncharacterized protein. (2642 aa)
	A0A4Y0BKC9	Uncharacterized protein. (2033 aa)
	A0A4Y0BK05	Uncharacterized protein. (1633 aa)
	A0A4Y0BJU3	Uncharacterized protein. (2644 aa)
	A0A4Y0BJM5	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1089 aa)
	A0A4Y0BJG9	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (666 aa)
	A0A4Y0BJG6	Uncharacterized protein. (644 aa)
	A0A4Y0BJC0	Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (1827 aa)
	A0A4Y0BJ69	Uncharacterized protein; Belongs to the DOCK family. (2214 aa)
	A0A4Y0BIT3	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
	A0A4Y0BIM7	Uncharacterized protein. (1926 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R219	A0A182R8E2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.737
A0A182R219	A0A182RAE5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.766
A0A182R219	A0A182RS41	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Phosphoinositide phospholipase C.	0.915
A0A182R219	A0A182RUL2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.788
A0A182R219	A0A182RW64	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.957
A0A182R219	A0A1Y9HE85	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.784
A0A182R219	A0A4Y0BGX0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.875
A0A182R219	A0A4Y0BHE3	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.631
A0A182R219	A0A4Y0BIA2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.631
A0A182R219	A0A4Y0BIM7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.875
A0A182R219	A0A4Y0BJM5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.904
A0A182R219	A0A4Y0BK05	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.875
A0A182R219	A0A4Y0BLU7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.959
A0A182R219	A0A4Y0BLW5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.917
A0A182R219	A0A4Y0BMS8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.959
A0A182R219	A0A4Y0BNK3	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.465
A0A182R219	A0A4Y0BRZ0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.959
A0A182R219	A0A4Y0BS96	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.904
A0A182R5P1	A0A4Y0BIG7	Uncharacterized protein; Belongs to the DOCK family.	Uncharacterized protein; Belongs to the DOCK family.	0.450
A0A182R5P1	A0A4Y0BJ69	Uncharacterized protein; Belongs to the DOCK family.	Uncharacterized protein; Belongs to the DOCK family.	0.449