(42 nodes) SH2 domain superfamily network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4Y0BJJ5	Tyrosine-protein kinase. (641 aa)
	A0A4Y0BK48	Uncharacterized protein. (978 aa)
	A0A4Y0BK05	Uncharacterized protein. (1633 aa)
	A0A4Y0BTF1	Uncharacterized protein. (420 aa)
	A0A4Y0BJI2	Uncharacterized protein. (809 aa)
	A0A4Y0BJ45	Uncharacterized protein. (711 aa)
	A0A4Y0BJ12	Tyrosine-protein kinase. (508 aa)
	A0A4Y0BIM7	Uncharacterized protein. (1926 aa)
	A0A4Y0BID7	Uncharacterized protein. (769 aa)
	A0A4Y0BH85	Uncharacterized protein. (1552 aa)
	A0A4Y0BGX0	Uncharacterized protein. (1995 aa)
	A0A4Y0BGP8	Uncharacterized protein. (548 aa)
	A0A4Y0BFZ0	Uncharacterized protein. (1082 aa)
	A0A4Y0BFA5	Tyrosine-protein kinase. (1170 aa)
	A0A4Y0BDI4	Tyrosine-protein kinase. (726 aa)
	A0A3F2YXQ7	Signal transducer and activator of transcription. (971 aa)
	A0A1Y9HF07	Tyrosine-protein kinase. (1272 aa)
	A0A182S133	SH2 domain-containing protein. (199 aa)
	A0A182RW87	Tyrosine-protein kinase. (1170 aa)
	A0A182RW64	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1218 aa)
	A0A182RT13	Uncharacterized protein. (948 aa)
	A0A182RRU0	Uncharacterized protein. (791 aa)
	A0A182RR66	Tyrosine-protein kinase. (537 aa)
	A0A182RQG3	Uncharacterized protein. (402 aa)
	A0A182RJG0	SH2 domain-containing protein. (359 aa)
	A0A182RGX8	Uncharacterized protein. (1554 aa)
	A0A182RGE0	Uncharacterized protein. (272 aa)
	A0A182REV7	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1855 aa)
	STAT-B	Signal transducer and activator of transcription. (736 aa)
	A0A182RA50	SH2 domain-containing protein. (380 aa)
	A0A182R7N8	Uncharacterized protein. (403 aa)
	A0A182R310	SH2 domain-containing protein. (362 aa)
	A0A182RM27	Uncharacterized protein. (490 aa)
	A0A4Y0BQ63	SH2 domain-containing protein. (1043 aa)
	A0A4Y0BPV3	Uncharacterized protein. (469 aa)
	A0A4Y0BPJ6	Uncharacterized protein. (1294 aa)
	A0A4Y0BP24	Tyrosine-protein kinase. (808 aa)
	A0A4Y0BNN1	Tyrosine-protein kinase. (816 aa)
	A0A4Y0BN26	Uncharacterized protein. (211 aa)
	A0A4Y0BKT7	Uncharacterized protein. (1703 aa)
	A0A4Y0BKH0	Uncharacterized protein. (779 aa)
	A0A4Y0BK79	Tyrosine-protein kinase. (676 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A182R7N8	A0A182RGE0	A0A182R7N8	A0A182RGE0	Uncharacterized protein.	Uncharacterized protein.	0.566
A0A182R7N8	A0A182RM27	A0A182R7N8	A0A182RM27	Uncharacterized protein.	Uncharacterized protein.	0.467
A0A182R7N8	A0A182RR66	A0A182R7N8	A0A182RR66	Uncharacterized protein.	Tyrosine-protein kinase.	0.726
A0A182R7N8	A0A182RT13	A0A182R7N8	A0A182RT13	Uncharacterized protein.	Uncharacterized protein.	0.491
A0A182R7N8	A0A182RW64	A0A182R7N8	A0A182RW64	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.740
A0A182R7N8	A0A182RW87	A0A182R7N8	A0A182RW87	Uncharacterized protein.	Tyrosine-protein kinase.	0.701
A0A182R7N8	A0A182S133	A0A182R7N8	A0A182S133	Uncharacterized protein.	SH2 domain-containing protein.	0.971
A0A182R7N8	A0A1Y9HF07	A0A182R7N8	A0A1Y9HF07	Uncharacterized protein.	Tyrosine-protein kinase.	0.745
A0A182R7N8	A0A4Y0BDI4	A0A182R7N8	A0A4Y0BDI4	Uncharacterized protein.	Tyrosine-protein kinase.	0.745
A0A182R7N8	A0A4Y0BFA5	A0A182R7N8	A0A4Y0BFA5	Uncharacterized protein.	Tyrosine-protein kinase.	0.701
A0A182R7N8	A0A4Y0BFZ0	A0A182R7N8	A0A4Y0BFZ0	Uncharacterized protein.	Uncharacterized protein.	0.832
A0A182R7N8	A0A4Y0BH85	A0A182R7N8	A0A4Y0BH85	Uncharacterized protein.	Uncharacterized protein.	0.726
A0A182R7N8	A0A4Y0BJ12	A0A182R7N8	A0A4Y0BJ12	Uncharacterized protein.	Tyrosine-protein kinase.	0.726
A0A182R7N8	A0A4Y0BJI2	A0A182R7N8	A0A4Y0BJI2	Uncharacterized protein.	Uncharacterized protein.	0.526
A0A182R7N8	A0A4Y0BJJ5	A0A182R7N8	A0A4Y0BJJ5	Uncharacterized protein.	Tyrosine-protein kinase.	0.660
A0A182R7N8	A0A4Y0BK48	A0A182R7N8	A0A4Y0BK48	Uncharacterized protein.	Uncharacterized protein.	0.526
A0A182R7N8	A0A4Y0BK79	A0A182R7N8	A0A4Y0BK79	Uncharacterized protein.	Tyrosine-protein kinase.	0.660
A0A182R7N8	A0A4Y0BKH0	A0A182R7N8	A0A4Y0BKH0	Uncharacterized protein.	Uncharacterized protein.	0.906
A0A182R7N8	A0A4Y0BKT7	A0A182R7N8	A0A4Y0BKT7	Uncharacterized protein.	Uncharacterized protein.	0.787
A0A182R7N8	A0A4Y0BN26	A0A182R7N8	A0A4Y0BN26	Uncharacterized protein.	Uncharacterized protein.	0.815