(43 nodes) Glutathione conjugation network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182R242	Uncharacterized protein. (608 aa)
	A0A182R4Y7	Uncharacterized protein. (655 aa)
	A0A182R7K7	Glutathione transferase microsomal. (152 aa)
	A0A182R9J8	Glutathione synthetase. (479 aa)
	A0A182RAB1	Uncharacterized protein. (574 aa)
	A0A182RAB2	Uncharacterized protein. (574 aa)
	A0A182RFM3	M20_dimer domain-containing protein. (483 aa)
	A0A182RH12	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (232 aa)
	A0A182RH80	Glutathione S-transferase; Belongs to the GST superfamily. (229 aa)
	A0A182RIR1	Uncharacterized protein. (580 aa)
	A0A182RM19	Glutathione S-transferase; Belongs to the GST superfamily. (234 aa)
	A0A182RQ85	Glutathione S-transferase. (222 aa)
	A0A182RRC4	Glutathione transferase microsomal. (147 aa)
	A0A182RRD4	Glutathione S-transferase; Belongs to the GST superfamily. (203 aa)
	A0A182RRD5	Glutathione S-transferase. (58 aa)
	A0A182RS14	Glutathione S-transferase; Belongs to the GST superfamily. (248 aa)
	A0A182RSI4	Glutathione S-transferase; Belongs to the GST superfamily. (233 aa)
	A0A182RSS0	Aldo_ket_red domain-containing protein. (285 aa)
	A0A182RXQ2	S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (283 aa)
	A0A182RYN4	Glutathione S-transferase; Belongs to the GST superfamily. (218 aa)
	A0A182RYP2	Glutathione S-transferase. (215 aa)
	A0A182RZA2	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (243 aa)
	A0A182S4J1	Glutathione S-transferase; Belongs to the GST superfamily. (222 aa)
	A0A182S4L7	Glutathione S-transferase; Belongs to the GST superfamily. (263 aa)
	A0A182S4P5	Glutathione S-transferase. (290 aa)
	A0A182S4P6	Glutathione S-transferase. (214 aa)
	A0A182S4P7	Glutathione S-transferase; Belongs to the GST superfamily. (214 aa)
	A0A182S4U0	Glutathione S-transferase. (224 aa)
	A0A182S4W4	Glutathione S-transferase; Belongs to the GST superfamily. (218 aa)
	A0A182S4W9	Glutathione S-transferase. (210 aa)
	A0A182S4X1	Glutathione S-transferase; Belongs to the GST superfamily. (216 aa)
	A0A182S4X2	Glutathione S-transferase; Belongs to the GST superfamily. (210 aa)
	A0A182S5E1	Glutathione S-transferase; Belongs to the GST superfamily. (219 aa)
	A0A182S5E2	Glutathione S-transferase; Belongs to the GST superfamily. (215 aa)
	A0A182S5E3	Glutathione S-transferase. (207 aa)
	A0A182S5E4	Glutathione S-transferase; Belongs to the GST superfamily. (209 aa)
	A0A1I8JU37	Glutathione transferase microsomal. (152 aa)
	A0A453YNK3	Uncharacterized protein. (1335 aa)
	A0A4Y0AMU4	Uncharacterized protein. (602 aa)
	A0A4Y0ARR1	Uncharacterized protein. (570 aa)
	A0A4Y0AYC8	Uncharacterized protein. (583 aa)
	A0A4Y0B3A3	Glutathione S-transferase; Belongs to the GST superfamily. (259 aa)
	A0A4Y0BL75	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (235 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R242	A0A182R4Y7	Uncharacterized protein.	Uncharacterized protein.	0.911
A0A182R242	A0A182R7K7	Uncharacterized protein.	Glutathione transferase microsomal.	0.494
A0A182R242	A0A182R9J8	Uncharacterized protein.	Glutathione synthetase.	0.864
A0A182R242	A0A182RAB1	Uncharacterized protein.	Uncharacterized protein.	0.712
A0A182R242	A0A182RAB2	Uncharacterized protein.	Uncharacterized protein.	0.711
A0A182R242	A0A182RFM3	Uncharacterized protein.	M20_dimer domain-containing protein.	0.575
A0A182R242	A0A182RH12	Uncharacterized protein.	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.817
A0A182R242	A0A182RH80	Uncharacterized protein.	Glutathione S-transferase; Belongs to the GST superfamily.	0.537
A0A182R242	A0A182RIR1	Uncharacterized protein.	Uncharacterized protein.	0.761
A0A182R242	A0A182RM19	Uncharacterized protein.	Glutathione S-transferase; Belongs to the GST superfamily.	0.537
A0A182R242	A0A182RQ85	Uncharacterized protein.	Glutathione S-transferase.	0.436
A0A182R242	A0A182RRC4	Uncharacterized protein.	Glutathione transferase microsomal.	0.494
A0A182R242	A0A182RRD4	Uncharacterized protein.	Glutathione S-transferase; Belongs to the GST superfamily.	0.574
A0A182R242	A0A182RRD5	Uncharacterized protein.	Glutathione S-transferase.	0.574
A0A182R242	A0A182RS14	Uncharacterized protein.	Glutathione S-transferase; Belongs to the GST superfamily.	0.911
A0A182R242	A0A182RSI4	Uncharacterized protein.	Glutathione S-transferase; Belongs to the GST superfamily.	0.645
A0A182R242	A0A182RSS0	Uncharacterized protein.	Aldo_ket_red domain-containing protein.	0.902
A0A182R242	A0A182RYN4	Uncharacterized protein.	Glutathione S-transferase; Belongs to the GST superfamily.	0.645
A0A182R242	A0A182RZA2	Uncharacterized protein.	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.899
A0A182R242	A0A182S4J1	Uncharacterized protein.	Glutathione S-transferase; Belongs to the GST superfamily.	0.645