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A0A4Y0ATV7 A0A4Y0ATV7 A0A182R7Q9 A0A182R7Q9 A0A182R7P1 A0A182R7P1 A0A182R7N9 A0A182R7N9 A0A182R7J2 A0A182R7J2 A0A4Y0BVD4 A0A4Y0BVD4 A0A4Y0BV17 A0A4Y0BV17 A0A4Y0BUT5 A0A4Y0BUT5 A0A182R259 A0A182R259 A0A182R4R2 A0A182R4R2 A0A182R5F4 A0A182R5F4 A0A182R636 A0A182R636 A0A182R637 A0A182R637 A0A182R649 A0A182R649 A0A182R6M1 A0A182R6M1 A0A182R6M3 A0A182R6M3 A0A182R6W6 A0A182R6W6 A0A182R6X0 A0A182R6X0 A0A182R721 A0A182R721 A0A182R7I4 A0A182R7I4 A0A182R7J1 A0A182R7J1 A0A4Y0BU72 A0A4Y0BU72 A0A4Y0BTR6 A0A4Y0BTR6 A0A4Y0BR49 A0A4Y0BR49 A0A4Y0BR05 A0A4Y0BR05 A0A4Y0BQU2 A0A4Y0BQU2 A0A182RWW5 A0A182RWW5 A0A182RW44 A0A182RW44 A0A182RV39 A0A182RV39 A0A182RUY6 A0A182RUY6 A0A182RRG9 A0A182RRG9 A0A182RRF4 A0A182RRF4 A0A182RQC4 A0A182RQC4 A0A182RQ99 A0A182RQ99 A0A182RQ07 A0A182RQ07 A0A182RP99 A0A182RP99 A0A182RP58 A0A182RP58 A0A182RP36 A0A182RP36 A0A182RMT1 A0A182RMT1 A0A182RMT0 A0A182RMT0 A0A182RLV4 A0A182RLV4 A0A182RKV3 A0A182RKV3 A0A182RKD6 A0A182RKD6 A0A182RJR0 A0A182RJR0 A0A182RIP3 A0A182RIP3 A0A182RHN6 A0A182RHN6 Adk3 Adk3 A0A182RGK6 A0A182RGK6 A0A182RDQ6 A0A182RDQ6 A0A182RDE2 A0A182RDE2 A0A182RCX4 A0A182RCX4 A0A182RCR6 A0A182RCR6 A0A182RCD6 A0A182RCD6 A0A182RBN1 A0A182RBN1 A0A182RBN0 A0A182RBN0 A0A182RBG7 A0A182RBG7 A0A182RB96 A0A182RB96 Adk2 Adk2 A0A4Y0BQ31 A0A4Y0BQ31 A0A4Y0BPY2 A0A4Y0BPY2 A0A4Y0BNW2 A0A4Y0BNW2 A0A4Y0BNG4 A0A4Y0BNG4 A0A4Y0BN01 A0A4Y0BN01 A0A4Y0BMZ8 A0A4Y0BMZ8 A0A4Y0BM71 A0A4Y0BM71 A0A4Y0BM50 A0A4Y0BM50 A0A4Y0BKI9 A0A4Y0BKI9 A0A4Y0BK41 A0A4Y0BK41 A0A4Y0BK14 A0A4Y0BK14 A0A4Y0BJE9 A0A4Y0BJE9 A0A4Y0BHK2 A0A4Y0BHK2 A0A4Y0BGN1 A0A4Y0BGN1 A0A4Y0BEW6 A0A4Y0BEW6 A0A4Y0BE32 A0A4Y0BE32 A0A4Y0BE07 A0A4Y0BE07 A0A4Y0BDX6 A0A4Y0BDX6 A0A4Y0BCR8 A0A4Y0BCR8 A0A4Y0BB37 A0A4Y0BB37 A0A4Y0B6Z8 A0A4Y0B6Z8 A0A4Y0B615 A0A4Y0B615 A0A4Y0AWS2 A0A4Y0AWS2 A0A182R802 A0A182R802 A0A4Y0APF3 A0A4Y0APF3 A0A4Y0AN68 A0A4Y0AN68 A0A1Y9HEN3 A0A1Y9HEN3 A0A1Y9HDS2 A0A1Y9HDS2 A0A182S563 A0A182S563 A0A182RYG0 A0A182RYG0 A0A182RYE0 A0A182RYE0 A0A182RX42 A0A182RX42
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A4Y0ATV7PRK domain-containing protein. (244 aa)
A0A182R7Q9dUTPase domain-containing protein. (146 aa)
A0A182R7P1Uncharacterized protein. (684 aa)
A0A182R7N9PfkB domain-containing protein. (383 aa)
A0A182R7J2Amidophosphoribosyltransferase. (545 aa)
A0A4Y0BVD4Uncharacterized protein. (529 aa)
A0A4Y0BV17Uncharacterized protein. (213 aa)
A0A4Y0BUT5Pribosyltran domain-containing protein. (187 aa)
A0A182R259Glyco_trans_2-like domain-containing protein. (458 aa)
A0A182R4R2Uncharacterized protein; Belongs to the 5'-nucleotidase family. (587 aa)
A0A182R5F4Uncharacterized protein. (582 aa)
A0A182R636Uncharacterized protein; Belongs to the 5'-nucleotidase family. (568 aa)
A0A182R637Uncharacterized protein; Belongs to the 5'-nucleotidase family. (574 aa)
A0A182R649dNK domain-containing protein. (272 aa)
A0A182R6M1Guanylate kinase-like domain-containing protein. (272 aa)
A0A182R6M3Glutaredoxin. (112 aa)
A0A182R6W6Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. Belongs to the adenylate kinase family. AK6 subfamily. (174 aa)
A0A182R6X0CN hydrolase domain-containing protein. (391 aa)
A0A182R721HD domain-containing protein. (451 aa)
A0A182R7I4Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (379 aa)
A0A182R7J1AIRC domain-containing protein. (427 aa)
A0A4Y0BU72Uncharacterized protein; Belongs to the 5'-nucleotidase family. (551 aa)
A0A4Y0BTR6Uncharacterized protein; Belongs to the adenylate kinase family. (199 aa)
A0A4Y0BR49PNP_UDP_1 domain-containing protein. (354 aa)
A0A4Y0BR05OMPdecase domain-containing protein. (496 aa)
A0A4Y0BQU2Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (298 aa)
A0A182RWW5UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (257 aa)
A0A182RW44Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (512 aa)
A0A182RV39Uncharacterized protein. (527 aa)
A0A182RUY6Uncharacterized protein. (358 aa)
A0A182RRG9Thioredoxin; Belongs to the thioredoxin family. (107 aa)
A0A182RRF4Importin N-terminal domain-containing protein. (989 aa)
A0A182RQC4Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (459 aa)
A0A182RQ99Uncharacterized protein. (1077 aa)
A0A182RQ07MGS domain-containing protein. (590 aa)
A0A182RP99Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1041 aa)
A0A182RP58Nucleoside diphosphate kinase. (168 aa)
A0A182RP36Thymidylate_kin domain-containing protein. (238 aa)
A0A182RMT1Uncharacterized protein. (238 aa)
A0A182RMT0Uncharacterized protein. (343 aa)
A0A182RLV45'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (302 aa)
A0A182RKV3Uridine kinase; Belongs to the uridine kinase family. (564 aa)
A0A182RKD6Uncharacterized protein; Belongs to the 5'-nucleotidase family. (576 aa)
A0A182RJR0Thymidylat_synt domain-containing protein. (305 aa)
A0A182RIP3Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (469 aa)
A0A182RHN6Uncharacterized protein. (659 aa)
Adk3GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (216 aa)
A0A182RGK6PfkB domain-containing protein. (349 aa)
A0A182RDQ6Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (188 aa)
A0A182RDE2Uncharacterized protein. (320 aa)
A0A182RCX4PRK domain-containing protein. (284 aa)
A0A182RCR6CMP/dCMP-type deaminase domain-containing protein. (199 aa)
A0A182RCD6CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (633 aa)
A0A182RBN1Uncharacterized protein. (1342 aa)
A0A182RBN0Uncharacterized protein. (1359 aa)
A0A182RBG7Uncharacterized protein; Belongs to the 5'-nucleotidase family. (612 aa)
A0A182RB96Nudix hydrolase domain-containing protein. (331 aa)
Adk2Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (240 aa)
A0A4Y0BQ31Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1382 aa)
A0A4Y0BPY2Uncharacterized protein; Belongs to the 5'-nucleotidase family. (557 aa)
A0A4Y0BNW2Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (328 aa)
A0A4Y0BNG4Uncharacterized protein; Belongs to the adenylate kinase family. (244 aa)
A0A4Y0BN01Uncharacterized protein. (2265 aa)
A0A4Y0BMZ8Uncharacterized protein. (633 aa)
A0A4Y0BM71Nudix hydrolase domain-containing protein. (336 aa)
A0A4Y0BM50Uncharacterized protein; Belongs to the 5'-nucleotidase family. (556 aa)
A0A4Y0BKI9OMPdecase domain-containing protein. (496 aa)
A0A4Y0BK41A_deaminase domain-containing protein. (338 aa)
A0A4Y0BK14AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (782 aa)
A0A4Y0BJE9AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (800 aa)
A0A4Y0BHK2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (772 aa)
A0A4Y0BGN1Amidohydro-rel domain-containing protein. (533 aa)
A0A4Y0BEW6Guanylate kinase-like domain-containing protein. (228 aa)
A0A4Y0BE32Amidohydro-rel domain-containing protein. (528 aa)
A0A4Y0BE07Glutaredoxin domain-containing protein. (112 aa)
A0A4Y0BDX6Guanylate kinase-like domain-containing protein. (267 aa)
A0A4Y0BCR8Guanylate kinase-like domain-containing protein. (210 aa)
A0A4Y0BB37Amidohydro-rel domain-containing protein. (602 aa)
A0A4Y0B6Z8Uncharacterized protein. (500 aa)
A0A4Y0B615Uncharacterized protein. (400 aa)
A0A4Y0AWS2Uncharacterized protein. (619 aa)
A0A182R802Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (466 aa)
A0A4Y0APF3Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (368 aa)
A0A4Y0AN68dNK domain-containing protein. (246 aa)
A0A1Y9HEN3Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (398 aa)
A0A1Y9HDS2Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (855 aa)
A0A182S563Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (156 aa)
A0A182RYG0Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
A0A182RYE0Amidohydro-rel domain-containing protein. (597 aa)
A0A182RX42SCHIP-1 domain-containing protein. (727 aa)
Your Current Organism:
Anopheles funestus
NCBI taxonomy Id: 62324
Other names: A. funestus
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