(60 nodes) Toll Like Receptor TLR6:TLR2 Cascade network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182RNS2	Uncharacterized protein. (381 aa)
	A0A182RNN3	Non-specific serine/threonine protein kinase. (588 aa)
	A0A182RNC9	Uncharacterized protein. (248 aa)
	A0A182RM62	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (380 aa)
	A0A182RL08	Uncharacterized protein. (241 aa)
	A0A182RJQ0	Uncharacterized protein. (206 aa)
	A0A182RJK7	UBIQUITIN_CONJUGAT_2 domain-containing protein. (143 aa)
	A0A182RIL0	Ubiquitin carboxyl-terminal hydrolase. (996 aa)
	A0A182RHT0	RNase_Zc3h12a domain-containing protein. (491 aa)
	A0A182RGF4	RHD domain-containing protein. (680 aa)
	A0A182RGB4	Mitogen-activated protein kinase. (376 aa)
	A0A182RGB3	Mitogen-activated protein kinase. (387 aa)
	A0A182RG65	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (395 aa)
	A0A182RG36	C2H2-type domain-containing protein. (447 aa)
	A0A182RFI3	40S ribosomal protein S27A. (156 aa)
	A0A182RD83	Protein kinase domain-containing protein. (645 aa)
	A0A182RD66	Protein kinase domain-containing protein. (1464 aa)
	A0A182RC61	Uncharacterized protein. (411 aa)
	A0A182RAR8	RNase_Zc3h12a domain-containing protein. (213 aa)
	A0A182RA43	C3H1-type domain-containing protein. (811 aa)
	A0A182R9P8	Uncharacterized protein. (594 aa)
	A0A182R9F3	Uncharacterized protein. (1141 aa)
	A0A182R7S1	Serine/threonine-protein phosphatase. (309 aa)
	A0A182R6J6	Protein kinase domain-containing protein. (804 aa)
	A0A182R1G8	Protein kinase domain-containing protein. (1128 aa)
	A0A182RQ68	Uncharacterized protein. (385 aa)
	A0A182RVX1	BZIP domain-containing protein. (458 aa)
	A0A182RX13	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	A0A182RX94	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (209 aa)
	A0A182RYM2	Uncharacterized protein. (494 aa)
	A0A182RZR2	CCHC NOA-type domain-containing protein. (546 aa)
	A0A1Y9HE64	Uncharacterized protein. (566 aa)
	A0A1Y9HET6	Mitogen-activated protein kinase kinase kinase 7-interacting protein. (456 aa)
	A0A4Y0ARF5	C3H1-type domain-containing protein. (927 aa)
	A0A4Y0AU14	Protein kinase domain-containing protein. (1364 aa)
	A0A4Y0B0X2	Protein kinase domain-containing protein. (597 aa)
	A0A4Y0B745	BZIP domain-containing protein. (515 aa)
	A0A4Y0B8I7	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (193 aa)
	A0A4Y0B9D6	BZIP domain-containing protein. (444 aa)
	A0A4Y0BEH6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1674 aa)
	A0A4Y0BEZ6	CCHC NOA-type domain-containing protein. (546 aa)
	A0A4Y0BF84	Uncharacterized protein. (609 aa)
	A0A4Y0BFS6	Regnase_1_C domain-containing protein. (225 aa)
	A0A4Y0BGR5	Uncharacterized protein. (913 aa)
	A0A4Y0BHQ8	Uncharacterized protein. (245 aa)
	A0A4Y0BI27	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (370 aa)
	A0A4Y0BI70	KxDL domain-containing protein. (254 aa)
	A0A4Y0BIF2	Mitogen-activated protein kinase. (358 aa)
	A0A4Y0BIT5	TMEM189_B_dmain domain-containing protein. (333 aa)
	A0A4Y0BK28	Uncharacterized protein. (1671 aa)
	A0A4Y0BKB4	Uncharacterized protein. (533 aa)
	A0A4Y0BKQ4	KxDL domain-containing protein. (254 aa)
	A0A4Y0BKS6	Uncharacterized protein. (1374 aa)
	A0A4Y0BL39	Uncharacterized protein. (129 aa)
	A0A4Y0BLS2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (392 aa)
	A0A4Y0BM58	Uncharacterized protein. (524 aa)
	A0A4Y0BN05	Uncharacterized protein. (970 aa)
	A0A4Y0BPT8	Uncharacterized protein. (1213 aa)
	A0A4Y0BS60	Uncharacterized protein. (1931 aa)
	Q06DG5_ANOFN	60S ribosomal protein L40. (128 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A182R1G8	A0A182R6J6	A0A182R1G8	A0A182R6J6	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.571
A0A182R1G8	A0A182RG65	A0A182R1G8	A0A182RG65	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.567
A0A182R1G8	A0A182RGB3	A0A182R1G8	A0A182RGB3	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.991
A0A182R1G8	A0A182RGB4	A0A182R1G8	A0A182RGB4	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.991
A0A182R1G8	A0A182RNC9	A0A182R1G8	A0A182RNC9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.972
A0A182R1G8	A0A182RNS2	A0A182R1G8	A0A182RNS2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.664
A0A182R1G8	A0A182RX13	A0A182R1G8	A0A182RX13	Protein kinase domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.620
A0A182R1G8	A0A182RX94	A0A182R1G8	A0A182RX94	Protein kinase domain-containing protein.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.581
A0A182R1G8	A0A182RZR2	A0A182R1G8	A0A182RZR2	Protein kinase domain-containing protein.	CCHC NOA-type domain-containing protein.	0.533
A0A182R1G8	A0A1Y9HET6	A0A182R1G8	A0A1Y9HET6	Protein kinase domain-containing protein.	Mitogen-activated protein kinase kinase kinase 7-interacting protein.	0.807
A0A182R1G8	A0A4Y0B0X2	A0A182R1G8	A0A4Y0B0X2	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.980
A0A182R1G8	A0A4Y0B8I7	A0A182R1G8	A0A4Y0B8I7	Protein kinase domain-containing protein.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.581
A0A182R1G8	A0A4Y0BEZ6	A0A182R1G8	A0A4Y0BEZ6	Protein kinase domain-containing protein.	CCHC NOA-type domain-containing protein.	0.533
A0A182R1G8	A0A4Y0BIF2	A0A182R1G8	A0A4Y0BIF2	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.851
A0A182R1G8	A0A4Y0BLS2	A0A182R1G8	A0A4Y0BLS2	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.894
A0A182R1G8	A0A4Y0BM58	A0A182R1G8	A0A4Y0BM58	Protein kinase domain-containing protein.	Uncharacterized protein.	0.498
A0A182R6J6	A0A182R1G8	A0A182R6J6	A0A182R1G8	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.571
A0A182R6J6	A0A182R7S1	A0A182R6J6	A0A182R7S1	Protein kinase domain-containing protein.	Serine/threonine-protein phosphatase.	0.454
A0A182R6J6	A0A182R9F3	A0A182R6J6	A0A182R9F3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.987
A0A182R6J6	A0A182R9P8	A0A182R6J6	A0A182R9P8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.434